DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment retm and SFH5

DIOPT Version :9

Sequence 1:	NP_001260132.1	Gene:	retm / 33899	FlyBaseID:	FBgn0031814	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	NP_012390.1	Gene:	SFH5 / 853296	SGDID:	S000003681	Length:	294	Species:	Saccharomyces cerevisiae

Alignment Length:	310	Identity:	70/310 - (22%)
Similarity:	111/310 - (35%)	Gaps:	96/310 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   227 ELRKMLDGV--------DDL------------ERVPSY-------QTILRFLAARDWHVSQAYAM 264
            :|:|.:.|:        |:|            |.|..|       :...:...|..:..|.....
Yeast    14 KLKKAIPGIIKEKCAGYDELYGYKLNPEGLTQEEVDKYYDEKIADRLTYKLCKAYQFEYSTIVQN 78

  Fly   265 LCDSLRWRREHRIDALLAEYSKPAVVVEHFPGGWHHLDKDGRPVYILRL---GHMDVKGLLKSL- 325
            |.|.|.||||  .:.|...|.:.           |:.:...  |.||..   |..:.|.:..:|
Yeast    79 LIDILNWRRE--FNPLSCAYKEV-----------HNTELQN--VGILTFDANGDANKKAVTWNLY 128

  Fly   326 -----------GMDGLLRLALHICEEGIQKIN-ESAERLEKPVLNWSLLV-DLEGLSMRHLWR-- 375
                       .:|..:|..:.:.|:|:..:: .|::.      |:...| |.:|:|   :||
Yeast   129 GQLVKKKELFQNVDKFVRYRIGLMEKGLSLLDFTSSDN------NYMTQVHDYKGVS---VWRMD 184

  Fly   376 PGIKALLNIIETV----ERNYPETMGRVLVVRAPRVFPIAWTIVSAFIDEHTRSKFLFYGPDCAH 436
            ..||   |..:||    ::.|||.:.....|..|.||...:.::..|:||.||.||:.
Yeast   185 SDIK---NCSKTVIGIFQKYYPELLYAKYFVNVPTVFGWVYDLIKKFVDETTRKKFVV------- 239

  Fly   437 MKDG--LAQYLDEEIVPDFLGGPCKTMIHEGGLVPKTLYKMNSLEDHDDE 484
            :.||  |.|||.:          |....:.|......|.|.|....|..|
Yeast   240 LTDGSKLGQYLKD----------CPYEGYGGKDKKNNLTKQNVTNVHPTE 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
retm	NP_001260132.1	PRELI	17..173	CDD:282550
		CRAL_TRIO_N	222..268	CDD:215024	11/67 (16%)
		CRAL_TRIO	293..456	CDD:279044	44/187 (24%)
SFH5	NP_012390.1	SEC14	101..263	CDD:214706	45/192 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810