DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment retm and AT1G72160

DIOPT Version :9

Sequence 1:	NP_001260132.1	Gene:	retm / 33899	FlyBaseID:	FBgn0031814	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	NP_177361.1	Gene:	AT1G72160 / 843547	AraportID:	AT1G72160	Length:	490	Species:	Arabidopsis thaliana

Alignment Length:	448	Identity:	108/448 - (24%)
Similarity:	182/448 - (40%)	Gaps:	108/448 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 TSPSDATKSPTLDQAS-----DQQHSILLD--GDFIARS--LGQLSPMQESKLLEL----RKMLD 233
            |..:...|....|:||     :::.|::..  |.|...|  |..||..::..|.||    |:.||
plant    75 TETASTEKQEVKDEASQKEVAEEKKSMIPQNLGSFKEESSKLSDLSNSEKKSLDELKHLVREALD 139

  Fly   234 --------------GVDDLERVPSYQTILRFLAARDWHVSQAYAMLCDSLRWRREHRIDALLAE- 283
                          |:..||...|...:|:||.||::.|..::|||.::::||:|.:||.|:.|
plant   140 NHQFTNTPEEVKIWGIPLLEDDRSDVVLLKFLRAREFKVKDSFAMLKNTIKWRKEFKIDELVEED 204

  Fly   284 ----YSKPAVVVEHFPGGWHHLDKDGRPVYILRLGHMDVKGLLKSLGMD-----GLLRLALHICE 339
                ..|...:        |..|::|.||.....|....|.|......|     ..||..:...|
plant   205 LVDDLDKVVFM--------HGHDREGHPVCYNVYGEFQNKELYNKTFSDEEKRKHFLRTRIQFLE 261

  Fly   340 EGIQKINESAERLEKPVLNWSLLVDLEGLSMRHLWRPGIKALLNIIETVERNYPETMGRVLVVRA 404
            ..|:|::.|:..: ..:...:.:.:..||..:.| |...|   ..:|.::.||||.:.:...:..
plant   262 RSIRKLDFSSGGV-STIFQVNDMKNSPGLGKKEL-RSATK---QAVELLQDNYPEFVFKQAFINV 321

  Fly   405 PRVFPIAWTIVSAFIDEHTRSKFLFYGPDCAHMKDGLAQYLDEEIVPDFLGG----PCKTMIHEG 465
            |..:.:.:|::..|:...::||.:|.||  :...:.|.:|:..|.||...||    ||
plant   322 PWWYLVFYTVIGPFMTPRSKSKLVFAGP--SRSAETLFKYISPEQVPVQYGGLSVDPC------- 377

  Fly   466 GLVPKTLYKMN---SLEDHDDEVTAELPTTAAAQALVPGK-------RLSANQQHDHRNLYKSVD 520
                    ..|   ||||...|:|.:..|....:.::..|       |::..:          |.
plant   378 --------DCNPDFSLEDSASEITVKPGTKQTVEIIIYEKCELVWEIRVTGWE----------VS 424

  Fly   521 LKAGF------AHELLIR-------NEDPKSVLTWDFDVMRNDLHFTLYRVTQELPEK 565
            .||.|      |:.::|:       :::|  |||..|.|  |:|...|..|.....:|
plant   425 YKAEFVPEEKDAYTVVIQKPRKMRPSDEP--VLTHSFKV--NELGKVLLTVDNPTSKK 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
retm	NP_001260132.1	PRELI	17..173	CDD:282550
		CRAL_TRIO_N	222..268	CDD:215024	19/63 (30%)
		CRAL_TRIO	293..456	CDD:279044	38/167 (23%)
AT1G72160	NP_177361.1	PRK11907	2..>97	CDD:237019	5/21 (24%)
		CRAL_TRIO_N	127..187	CDD:397711	19/59 (32%)
		SEC14	203..372	CDD:238099	41/183 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	71	1.000	Inparanoid score	I2453
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.860