DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment retm and Sec14l3

DIOPT Version :9

Sequence 1:	NP_001260132.1	Gene:	retm / 33899	FlyBaseID:	FBgn0031814	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	NP_072130.1	Gene:	Sec14l3 / 64543	RGDID:	620812	Length:	400	Species:	Rattus norvegicus

Alignment Length:	411	Identity:	105/411 - (25%)
Similarity:	194/411 - (47%)	Gaps:	59/411 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 LGQLSPMQESKLLELRKMLDGVDDLERVPSYQTILRFLAARDWHVSQAYAMLCDSLRWRREHRID 278
            :|.|||.|...|.:.|:.:..|......|....:||:|.||::.:.::.|||...:.:|:...||
  Rat     5 VGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQKSEAMLRKYMEFRKTMDID 69

  Fly   279 ALLAEYSKPAVVVEHFPGGWHHLDKDGRPVYILRLGHMDVKGLLKSLGMDGLLRLALHICEEGIQ 343
            .:| ::..|.|:.::.|||....|:||.|::...:|.:|.||||.|:....||:..:..||..:.
  Rat    70 HIL-DWQPPEVIQKYMPGGLCGYDRDGCPLWYDIIGPLDPKGLLFSVTKQDLLKTKMRDCERILH 133

  Fly   344 KINESAERLEKPVLNWSLLVDLEGLSMRHLWRPGIKALLNIIETVERNYPETMGRVLVVRAPRVF 408
            :.:...|||.:.:....::.|.|||.::|.|:|.::........:|.|||||:..:|:|:|.::|
  Rat   134 ECDLQTERLGRKIETIVMIFDCEGLGLKHFWKPLVEVYQEFFGLLEENYPETLKFMLIVKATKLF 198

  Fly   409 PIAWTIVSAFIDEHTRSKFLFYGPDCAHMKDGLAQYLDEEIVPDFLGG---------PCKTMIHE 464
            |:.:.::..|:.|.||.|.:..|..   .|:||.:.:..|.:|...||         .|.|.|:.
  Rat   199 PVGYNLMKPFLSEDTRRKIVVLGNS---WKEGLLKLISPEELPAHFGGTLTDPDGNPKCLTKINY 260

  Fly   465 GGLVPKTLYKMNSLEDHDDEVTAELPTTAAAQALVPGKRLSANQQHDHRNLYKSVDLKAGFAHEL 529
            ||.:||::|..:.::                            .|::|     ||.:..|.:|::
  Rat   261 GGEIPKSMYVRDQVK----------------------------TQYEH-----SVQISRGSSHQV 292

  Fly   530 LIRNEDPKSVLTWDFDVMRNDLHFTLYRVTQELPEKNDSAVSYFDLQDFVEGVNY----FREEPT 590
            ......|..||.|.|.....|:.|.::..| ::.|:..:.    ::.:.:....|    ..|:.:
  Rat   293 EYEILFPGCVLRWQFSSDGADIGFGVFLKT-KMGERQKAG----EMTEVLTSQRYNAHMVPEDGS 352

  Fly   591 LICRHKESVQGSHVMHHNDSY 611
            |.|    :..|.:|:..:::|
  Rat   353 LTC----TEAGVYVLRFDNTY 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
retm	NP_001260132.1	PRELI	17..173	CDD:282550
		CRAL_TRIO_N	222..268	CDD:215024	12/45 (27%)
		CRAL_TRIO	293..456	CDD:279044	50/162 (31%)
Sec14l3	NP_072130.1	CRAL_TRIO_N	13..59	CDD:215024	12/45 (27%)
Sec14l3	NP_072130.1	SEC14	76..245	CDD:214706	54/171 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	1	1.000	-	-		FOG0000197
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820