DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment retm and sec14l7

DIOPT Version :9

Sequence 1:	NP_001260132.1	Gene:	retm / 33899	FlyBaseID:	FBgn0031814	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	XP_009303977.1	Gene:	sec14l7 / 566865	ZFINID:	ZDB-GENE-141216-145	Length:	405	Species:	Danio rerio

Alignment Length:	433	Identity:	125/433 - (28%)
Similarity:	212/433 - (48%)	Gaps:	69/433 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   201 HSILLDGDFIARSLGQLSPMQESKLLELRKMLDGV-DDLERVPSYQT---ILRFLAARDWHVSQA 261
            :|.|:....::..:|.|||.|...|.:.|:.|:.| |.|    |.||   :||:|.||.::|.:|
Zfish     5 NSALIYSAKMSGRVGDLSPKQAEALTQFREKLEDVWDQL----SNQTDHYLLRWLRARTFNVPKA 65

  Fly   262 YAMLCDSLRWRREHRIDALLAEYSKPAVVVEHFPGGWHHLDKDGRPVYILRLGHMDVKGLLKSLG 326
            .|||...|.:||..:::.::.::|.|.|:..:..||....|::|.|::...:|.:|.||||.|..
Zfish    66 EAMLRKHLEFRRHMKLETIIDDWSPPEVLERYVAGGMCGYDREGSPIWFDIIGPLDPKGLLLSAS 130

  Fly   327 MDGLLRLALHICEEGIQKINESAERLEKPVLNWSLLVDLEGLSMRHLWRPGIKALLNIIETVERN 391
            ....||..:...|...::..:.:::|.|.:.:.:::.|.|||.|:|||:|.::....|:...|.|
Zfish   131 KQDCLRTKIRDAELLRRECEKQSKKLGKHIESITIIYDCEGLGMKHLWKPAVEMYGEILTMYEEN 195

  Fly   392 YPETMGRVLVVRAPRVFPIAWTIVSAFIDEHTRSKFLFYGPDCAHMKDGLAQYLDEEIVPDFLGG 456
            |||::.:||:::||::||||:.:|..|:.|.||.|....|   ::.||.|..|:|.:.:|...||
Zfish   196 YPESLKKVLLIKAPKLFPIAYNLVKHFLREETRQKIAVLG---SNWKDVLKNYVDADQIPAAYGG 257

  Fly   457 P---------CKTMIHEGGLVPKTLYKMNSLE-DHDDEVTAELPTTAAAQALVPGKRLSANQQHD 511
            .         |.||:..||:|||:.|..:|:: .::..:|.              .|.||:|
Zfish   258 SLTDPDGNPLCTTMLRYGGVVPKSYYVRDSIKVQYEQNITI--------------SRGSAHQ--- 305

  Fly   512 HRNLYKSVDLKAGFAHELLIRNEDPKSVLTWDFDVMRNDLHFTLYRVTQELPEKNDSAVSYFDLQ 576
                         ..:|||.    |..:|.|.|....:|:.|.|:     |..|........|:|
Zfish   306 -------------IEYELLF----PNCLLRWQFASEGSDIGFGLF-----LKTKGSETKKVEDMQ 348

  Fly   577 DFVEGVNY----FREEPTLICRHKESVQGSHVMHHNDSY-LMH 614
            :.:....|    ..||.:..|..    .|.:|:..::|| ::|
Zfish   349 EILRNERYNAHLVPEEGSYTCEE----PGIYVVRFDNSYSVLH 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
retm	NP_001260132.1	PRELI	17..173	CDD:282550
		CRAL_TRIO_N	222..268	CDD:215024	19/49 (39%)
		CRAL_TRIO	293..456	CDD:279044	53/162 (33%)
sec14l7	XP_009303977.1	CRAL_TRIO_N	26..72	CDD:215024	19/49 (39%)
		CRAL_TRIO	97..258	CDD:279044	54/163 (33%)
		GOLD_2	317..395	CDD:290608	19/80 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	1	1.000	-	-		FOG0000197
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X399
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920