Protein Alignment retm and sec14l5

DIOPT Version :10

• Sequence 1: NP_001260132.1
• Gene: retm / 33899
• FlyBaseID: FBgn0031814
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: XP_031749906.1
• Gene: sec14l5 / 493292
• XenbaseID: XB-GENE-953433
• Length: 793
• Species: Xenopus tropicalis
• Alignment Length: 739
• Identity: 322/739 - (43%)
• Similarity: 441/739 - (59%)
• Gaps: 103/739 - (13%)

  Fly     1 MVQKFQSPVRVYKYPFELVMKAYERRFPTCPQMPIVLDCEVIKDESLEDGAKRNTSRRCKLAVDA 65
            ||||:||||||||:.|||:|.||||||||||.:|:.:..:::.:...||||.....|||||.|||
 Frog     1 MVQKYQSPVRVYKHGFELIMAAYERRFPTCPLIPMFVGSDLMNEYKSEDGAVHIVERRCKLDVDA 65

  Fly    66 PYIFKKLIGVDHVYFLQHNFLDLANRTLSIEAVNESFSSRIEIFERCRYYAHPDNSEWTCFDQSA 130
            |.:.||:.|||:|||:|.|.|:...|||.|||.||:|||||.:.|.|.|..||||..||||:|||
 Frog    66 PRLLKKIAGVDYVYFIQKNSLNRQERTLHIEAYNETFSSRIIVNEHCCYTVHPDNENWTCFEQSA 130

  Fly   131 TLDIKNFFGFEHSMEKMGMKQYTQTTLKGKEIIEFFIGQLREEGITHVERWT---SPSDATKSPT 192
            :||||:|||||.::||:.|||||....|||||||:::.||.:||||.:.|||   :....||:.|
 Frog   131 SLDIKSFFGFESTVEKIAMKQYTTNIKKGKEIIEYYLNQLEQEGITSMPRWTPEIAQRQETKTDT 195

  Fly   193 LDQASDQQHSI-------------------------------LLDGDFIARSLGQLSPMQESKLL 226
            ..:|.....||                               .||.|:|.|.||.|:|:|||.|:
 Frog   196 SGRAMSPPQSIPTKSADGPSSKDGLPSSPTAATHELSSTPDDKLDADYIKRYLGDLTPLQESCLI 260

  Fly   227 ELRKMLDGVDDLERVPSYQTILRFLAARDWHVSQAYAMLCDSLRWRREHRIDALLAEYSKPAVVV 291
            .||:.|..... .::|..:.|||||.|||:::.:|..:||.||.||::|.:|.||:.:..|.|:.
 Frog   261 RLRQWLQETHK-GKIPKDEHILRFLRARDFNIDKAREILCQSLTWRKQHHVDYLLSTWDPPQVLH 324

  Fly   292 EHFPGGWHHLDKDGRPVYILRLGHMDVKGLLKSLGMDGLLRLALHICEEGIQKINESAERLEKPV 356
            :::.|||||.|:||||:|:||||.||.|||:::||.:.|||..|.|.|||:::..|:.....:|:
 Frog   325 DYYAGGWHHHDRDGRPLYVLRLGQMDTKGLVRALGEESLLRHVLSINEEGLRRCEENTNIFGRPI 389

  Fly   357 LNWSLLVDLEGLSMRHLWRPGIKALLNIIETVERNYPETMGRVLVVRAPRVFPIAWTIVSAFIDE 421
            .:|:.|||||||:||||||||:||||.|||.||.|||||:||:|::|||||||:.||:||.||||
 Frog   390 SSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDE 454

  Fly   422 HTRSKFLFYGPDCAHMKDGLAQYLDEEIVPDFLGGPCKTMIHEGGLVPKTLYKM-NSLEDHDDEV 485
            :||.|||.|..:......||..|:|:|::||||||.|...:.|||:|||.||:. ..||:.|..:
 Frog   455 NTRKKFLIYAGNDYQGPGGLIDYIDKEVIPDFLGGECMCEVSEGGMVPKALYRTPEELENDDIRL 519

  Fly   486 TAELPTTAAAQALVPGKRLSANQQHDHRNLYKSVDLKAGFAHELLIRNEDPKSVLTWDFDVMRND 550
            ..|                         .:|:|..:..|..||:||:..|..||:||||||.:.|
 Frog   520 WTE-------------------------TIYQSASVFKGSPHEILIQIVDASSVITWDFDVCKGD 559

  Fly   551 LHFTLYRVTQELPE--KNDSA------------VSYFDLQDFVEGVNYFREEPTLICRHKESVQG 601
            :.|.:|. ::..|:  |.|:.            |...| :.:..|.:|...|..|||:..|||||
 Frog   560 IVFNIYH-SKRAPQAPKRDTLGAHGITSPVGNNVQLID-KAWQLGRDYSMVESPLICKEGESVQG 622

  Fly   602 SHVMHHNDSYLMHW----------------------FSPSGAQLNVFY--EVLSSANYKGSMTSL 642
            |||......|::.|                      ...|..:..|.|  |::.|.:::||||||
 Frog   623 SHVTRWPGFYILQWKFHSMPACATSSLPRVEDVLASLQVSSHKCKVMYYTEIIGSEDFRGSMTSL 687

  Fly   643 QSAFS--SNSSAASSVQSRXYEKA 664
            :|:.|  |..|||::..|:.:..:
 Frog   688 ESSHSGFSQLSAATTSSSQSHSSS 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
retm	NP_001260132.1	PRELI	17..173	CDD:398400	90/155 (58%)
		CRAL_TRIO_N	222..268	CDD:215024	18/45 (40%)
		CRAL_TRIO	293..456	CDD:459890	95/162 (59%)
sec14l5	XP_031749906.1	PRELI	17..173	CDD:398400	90/155 (58%)
		CRAL_TRIO_N	256..301	CDD:215024	18/45 (40%)
		CRAL_TRIO	326..489	CDD:459890	95/162 (59%)