DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment retm and rlbp1a

DIOPT Version :9

Sequence 1:	NP_001260132.1	Gene:	retm / 33899	FlyBaseID:	FBgn0031814	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	NP_956999.1	Gene:	rlbp1a / 393678	ZFINID:	ZDB-GENE-040426-1662	Length:	312	Species:	Danio rerio

Alignment Length:	292	Identity:	70/292 - (23%)
Similarity:	122/292 - (41%)	Gaps:	59/292 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 DATKSPTLDQASDQQHSILLDGDFIARSLGQLSPMQESKLLELRKML-------DGV-----DDL 238
            |.||....|:                  |.:....:.|.:.|||.|:       |.|     |..
Zfish    41 DHTKQKAKDE------------------LNETDEKRASAIKELRAMIKDKAGQGDEVAKTVQDKF 87

  Fly   239 ERVPSYQTILRFLAARDWHVSQAYAMLCDSLRWRREHRIDALLAEYSKPAVVVEHFPGGWHHL-- 301
            .:.|. ..:|||:.||.:.|::|:.::...:|:||::   ..|.|...|..|......|:..:
Zfish    88 GKEPD-SLLLRFIRARKFDVARAHELMKGYVRFRRDY---PELFENLTPEAVRSTIEAGYPRILS 148

  Fly   302 --DKDGRPVYILRLGHMDVKGLLKSLGMDGLLRLALHICEEGIQKINESAERLEKPVLNWSLLVD 364
              ||:||.|.:..:.:.|    |:.:..|..||....|.|:.::  ||     |..:..:.|:.:
Zfish   149 TRDKNGRVVLLFNIDNWD----LEEVTFDETLRAYCVILEKLLE--NE-----ETQINGFVLIEN 202

  Fly   365 LEGLSMRHLWRPGIK--ALLNIIETVERNYPETMGRVLVVRAPRVFPIAWTIVSAFIDEHTRSKF 427
            .:|.:|:|  ..|||  .|..:::.::.::|.....|.|:..|..|...:.:|..|:......:.
Zfish   203 FKGFTMQH--ASGIKHTELKKMVDMLQDSFPARFKAVHVIHQPWYFTTTYNVVKPFMKSKLLERV 265

  Fly   428 LFYGPDCAHMKDGLAQYLDEEIV-PDFLG-GP 457
            ..:|.:.    ||..:....||: |||.| ||
Zfish   266 FVHGDEL----DGYLRDFGAEILPPDFDGTGP 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
retm	NP_001260132.1	PRELI	17..173	CDD:282550
		CRAL_TRIO_N	222..268	CDD:215024	16/57 (28%)
		CRAL_TRIO	293..456	CDD:279044	40/170 (24%)
rlbp1a	NP_956999.1	CRAL_TRIO_N	59..116	CDD:215024	16/57 (28%)
rlbp1a	NP_956999.1	CRAL_TRIO	142..291	CDD:279044	39/165 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820