DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment retm and CG33523

DIOPT Version :9

Sequence 1:	NP_001260132.1	Gene:	retm / 33899	FlyBaseID:	FBgn0031814	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	NP_001261457.1	Gene:	CG33523 / 38668	FlyBaseID:	FBgn0053523	Length:	654	Species:	Drosophila melanogaster

Alignment Length:	489	Identity:	99/489 - (20%)
Similarity:	178/489 - (36%)	Gaps:	115/489 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   237 DLERVPS-YQTILRFLAARDWHVSQAYAMLCDSLRWRRE---HRID--ALLAEYSKPAVVVEHFP 295
            |::|:.: :..:.|||...|..:..::..|.::...|:.   :.||  .|..||.|...|..
  Fly    37 DIDRIRNDHLWLQRFLEMYDLDMETSFNSLWETCILRQSTGANDIDESELNQEYLKEGSVFV--- 98

  Fly   296 GGWHHLDKDGRPVYILRLGHMDVKGLLKSLGMDGLLRLALHICEEGIQKINESAERLEKPVLNWS 360
               |:.|.||:|:.:.|     ||...||..:|.|:|:.::..|.         .:.|:.:...:
  Fly    99 ---HNTDVDGKPLLVFR-----VKMHSKSKNLDELIRIVVYWVER---------TQREQHLTQLT 146

  Fly   361 LLVDLEGLSMRHLWRPGIKALLNIIETVERNYPETMGRVLVVRAPRVFPIAWTIVSAFIDEHTRS 425
            :..|:.|.|:..:   .::.:..|:||.::.||.::..:||.....|...|:.::.|.:.
  Fly   147 IFFDMSGTSLASM---DLEFVKRIVETFKQFYPNSLNYILVYELGWVLNAAFKVIKAVLP----- 203

  Fly   426 KFLFYGPDCAHM-----KDGLAQYLDEEIVPDFLGGPCKTMIHEGGLVP---KTLYKMNSLEDHD 482
                  |....:     |..:.||::::......||...   :|...||   |.:.|..:....|
  Fly   204 ------PKAVEILKMISKKDINQYINKDNCLAIWGGEDN---YEFSFVPEAKKVISKPVAANAGD 259

  Fly   483 DEVTAELPTTAAAQALVPGKRLSANQQHD------HRNLYKSVDLKAGFAHELLIRNEDPKSVLT 541
            |:..|:...|....|.:..|..:.|:.|.      |.|....|:..:..|...:.......|.:|
  Fly   260 DDQFADKKVTFVDSAPMVLKETNINKMHTPSEGMLHINPKDFVNFNSKNAEATMTIKSIATSAVT 324

  Fly   542 WDFDVMRNDLHFTLYRVTQELPEKNDSAVSYFDLQDFVEGVNYFREEPT--LICRHKES-----V 599
                          |::....|||                   ||..|.  :|..::|:     :
  Fly   325 --------------YKIQTTSPEK-------------------FRVRPRCGIIQPNQEATINIWL 356

  Fly   600 QGSHVMHHN--DSYL-MHWFSP----SGAQLNVFYEVLSSANYKGSMTSLQSAFSSNSSAA---- 653
            :..|.:..:  |.:| |...:|    .||.:...:...|..:.......|...|..|.|.|
  Fly   357 KSEHKLSDDSKDKFLVMAMVAPGGECGGADVTELWRSKSPTSADVEQHRLVCRFDENKSKAQLDC 421

  Fly   654 ---SSVQSRXYEKAGDGGTNGAEWRSPALEEPIA 684
               ||..|....|....|.:.|    .|:|..:|
  Fly   422 ASKSSKASVDCSKKSGAGVDPA----TAMERQLA 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
retm	NP_001260132.1	PRELI	17..173	CDD:282550
		CRAL_TRIO_N	222..268	CDD:215024	7/31 (23%)
		CRAL_TRIO	293..456	CDD:279044	32/167 (19%)
CG33523	NP_001261457.1	CRAL_TRIO	94..234	CDD:279044	34/173 (20%)
CG33523	NP_001261457.1	Motile_Sperm	293..396	CDD:279029	22/135 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810