DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment retm and Ku80

DIOPT Version :9

Sequence 1:	NP_001260132.1	Gene:	retm / 33899	FlyBaseID:	FBgn0031814	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	NP_609767.2	Gene:	Ku80 / 34930	FlyBaseID:	FBgn0041627	Length:	699	Species:	Drosophila melanogaster

Alignment Length:	307	Identity:	56/307 - (18%)
Similarity:	96/307 - (31%)	Gaps:	117/307 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LVMKAYERRFPTCPQMPIVLDCEVIKDESLEDGAKRNTSRRCKLAVDAPYIFKKLIGVDHVYFLQ 82
            |..|.|..:| ..|||.::|.                     :||.|.......::.|.  |..|
  Fly   363 LCWKIYSTKF-NRPQMVVLLP---------------------RLADDTHPATLYMLEVS--YTSQ 403

  Fly    83 HNFLDL-ANRTLSIEAVNESFSSRIEIFE----RCRYYAHPDNSEW------------TCFDQSA 130
            |:|.|. |.||...|...|..::..::.:    .|..........|            :.|:|:.
  Fly   404 HHFWDFPALRTTKTECSEEQLNAIDQLIDSTDLECTLRDTQQPRPWAQNDLLPFDALPSIFEQNV 468

  Fly   131 TLDIKNFFGFEHSME-KMGMKQYTQTTLKGKEIIEFFIGQLREEGITHVERWTSPSDATKSPTLD 194
            ...::....:::..| ||         ||.|...:.|              |..|.      .|:
  Fly   469 MDILERKVIYDNDKEDKM---------LKDKNFADVF--------------WRVPD------PLE 504

  Fly   195 QASDQQHSILLDGDFIARSLGQLSPMQ-----ESKLL------------------ELRKMLDGVD 236
            :.|.:..:|          :.:|.|::     :.|||                  |:....|||.
  Fly   505 EKSKRAAAI----------VKKLFPLRYSRAWQEKLLAKEQAENGVAVKSEPAEKEIPLPSDGVG 559

  Fly   237 DLERVPSYQTILRFLAARDWHVSQAYAMLCDSLRWRREHRIDALLAE 283
            .::.:..::.:|    |....:|.|         ..|:.|..||.|:
  Fly   560 LIDPISDFRRVL----ASVHTISNA---------TERDARFQALAAD 593

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
retm	NP_001260132.1	PRELI	17..173	CDD:282550	33/172 (19%)
		CRAL_TRIO_N	222..268	CDD:215024	11/63 (17%)
		CRAL_TRIO	293..456	CDD:279044
Ku80	NP_609767.2	Ku_N	7..213	CDD:281693
		KU80	221..524	CDD:238445	40/223 (18%)
		Ku_PK_bind	562..663	CDD:285938	9/45 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900