DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment retm and ttpa

DIOPT Version :9

Sequence 1:	NP_001260132.1	Gene:	retm / 33899	FlyBaseID:	FBgn0031814	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	NP_956025.2	Gene:	ttpa / 325906	ZFINID:	ZDB-GENE-030131-4631	Length:	285	Species:	Danio rerio

Alignment Length:	307	Identity:	68/307 - (22%)
Similarity:	131/307 - (42%)	Gaps:	39/307 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   189 KSPTLDQASDQQHSILLDGDFIARSLGQLSPMQESKLLELRKMLDGVDDLERVPSYQTILRFLAA 253
            ||..:|: :::.:::.:|...||..|.:|....|:   |||     :.||:...::  ::|||.|
Zfish     2 KSEEVDE-TEELNNLPVDSSRIAPYLSELKEKAEA---ELR-----IRDLDLSKTF--LIRFLQA 55

  Fly   254 RDWHVSQAYAMLCDSLRWRRE-HRIDALLAEYSKPAVVVEHFPGGWHHLDKDGRPVYILRLGHMD 317
            ||:.|:.|..:|.:..:||:| ..|.|.|...|...::..::.|.....|..|..|.|.|:|
Zfish    56 RDFDVALALKLLINYHKWRQECPEITADLRPSSVIGLLQNNYHGVLRSRDDAGSRVLIYRIG--- 117

  Fly   318 VKGLLKSLGMDGLLRLALHICEEGIQKINESAERLEKPVLNWSLLVDLEGLSMRHLWRPGIKALL 382
             |...|......:.|::|...|..:|:.......|:       .:.||:.....|..:.......
Zfish   118 -KWNPKEFTAYEVFRVSLITSELIVQEWETQRNGLK-------AIFDLQDWCFAHALQINPSLAK 174

  Fly   383 NIIETVERNYPETMGRVLVVRAPRVFPIAWTIVSAFIDEHTRSKFLFYGPDCAHMKDGLAQYLDE 447
            .|...:..::|..:..:.::..|..|...:.::..|:.:..:.:...:|  |::.: .|..|..:
Zfish   175 KISSVLTDSFPLKVRGIHLINEPIFFRPVFAMIRPFLPDKIKQRIHMHG--CSYAR-SLCNYFPK 236

  Fly   448 EIVPDFLGGPCKTMIHEGGLVPK-----TLYKMNSLEDHDDEVTAEL 489
            .::|...||       .|..|.:     |.|.|.| ||:...::.:|
Zfish   237 AVLPPVYGG-------TGPSVDEVCQEWTEYIMQS-EDYLHRLSVDL 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
retm	NP_001260132.1	PRELI	17..173	CDD:282550
		CRAL_TRIO_N	222..268	CDD:215024	15/45 (33%)
		CRAL_TRIO	293..456	CDD:279044	27/162 (17%)
ttpa	NP_956025.2	CRAL_TRIO_N	26..70	CDD:215024	17/53 (32%)
ttpa	NP_956025.2	CRAL_TRIO	97..246	CDD:279044	29/169 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810