DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment retm and Rlbp1

DIOPT Version :9

Sequence 1:	NP_001260132.1	Gene:	retm / 33899	FlyBaseID:	FBgn0031814	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	NP_001099744.1	Gene:	Rlbp1 / 293049	RGDID:	1309649	Length:	317	Species:	Rattus norvegicus

Alignment Length:	304	Identity:	71/304 - (23%)
Similarity:	128/304 - (42%)	Gaps:	51/304 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   192 TLDQASDQQHSILLDGDFIARSLGQLSPMQESKLLELRKMLDGVDDLERVPSYQT--ILRFLAAR 254
            ||.:|.|:.:......|...|.|.:|...|.:...||     .|...|||.:..:  :|||:.||
  Rat    44 TLQKAKDELNEREETRDEAVRELQELVQAQAASGEEL-----AVAVAERVQARDSAFLLRFIRAR 103

  Fly   255 DWHVSQAYAMLCDSLRWRREH--RIDALLAEYSKPAVVVEHFPGGWHHLDKDGRPVYILRLGHMD 317
            .:.|.:||.:|...:.:|.::  ..|:|..|..: ..:...:||.....||.||.|.:..:.:..
  Rat   104 KFDVGRAYELLKGYVNFRLQYPELFDSLSMEALR-CTIEAGYPGVLSSRDKYGRVVMLFNIENWH 167

  Fly   318 VKGLLKSLGMDGLLRLALHICEEGIQKINESAERLEKPVLNWSLLVDLEGLSMRHL--WRPGIKA 380
                .:.:..|.:|:....|.|:.::  ||     |..:..:.::.:.:|.:|:..  .||  ..
  Rat   168 ----CEEVTFDEILQAYCFILEKLLE--NE-----ETQINGFCIVENFKGFTMQQAAGLRP--SD 219

  Fly   381 LLNIIETVERNYPETMGRVLVVRAPRVFPIAWTIVSAFIDEHTRSKFLFYGPDCAHMKDGLAQYL 445
            |..:::.::.::|.....:..:..|..|...:.:|..|:......:...:|.|.    ||..|.:
  Rat   220 LKKMVDMLQDSFPARFKAIHFIHQPWYFTTTYNVVKPFLKNKLLQRVFVHGDDL----DGFFQEI 280

  Fly   446 DEEIVP-DFLGGPCKTMIHEGGLVPKTLYKMNSLEDHDDEVTAE 488
            ||.|:| ||           ||.:||          :|.:|.||
  Rat   281 DENILPADF-----------GGTLPK----------YDGKVVAE 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
retm	NP_001260132.1	PRELI	17..173	CDD:282550
		CRAL_TRIO_N	222..268	CDD:215024	15/47 (32%)
		CRAL_TRIO	293..456	CDD:279044	35/165 (21%)
Rlbp1	NP_001099744.1	CRAL_TRIO_N	60..117	CDD:215024	20/61 (33%)
Rlbp1	NP_001099744.1	CRAL_TRIO	143..292	CDD:279044	36/176 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820