Protein Alignment retm and Sec14l5

DIOPT Version :10

• Sequence 1: NP_001260132.1
• Gene: retm / 33899
• FlyBaseID: FBgn0031814
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_001129182.2
• Gene: Sec14l5 / 287060
• RGDID: 1564638
• Length: 696
• Species: Rattus norvegicus
• Alignment Length: 727
• Identity: 311/727 - (42%)
• Similarity: 436/727 - (59%)
• Gaps: 108/727 - (14%)

  Fly     1 MVQKFQSPVRVYKYPFELVMKAYERRFPTCPQMPIVLDCEVIKDESLEDGAKRNTSRRCKLAVDA 65
            ||||:|||||||||||||||.|||:||||||.:|:.|..||:.:....|||.....|.|:|.|||
  Rat     1 MVQKYQSPVRVYKYPFELVMAAYEKRFPTCPLIPVFLGSEVLSECRSADGAVHTVERSCRLRVDA 65

  Fly    66 PYIFKKLIGVDHVYFLQHNFLDLANRTLSIEAVNESFSSRIEIFERCRYYAHPDNSEWTCFDQSA 130
            |.:.:|:.||:||.|:|.|.|:...|||.|:|.||:|:||:.:.|.|||..||:|.:||||:|||
  Rat    66 PRLLRKIAGVEHVVFIQRNVLNWRERTLLIDAHNETFASRVTVKEHCRYTVHPENEDWTCFEQSA 130

  Fly   131 TLDIKNFFGFEHSMEKMGMKQYTQTTLKGKEIIEFFIGQLREEGITHVERWT------------- 182
            :||:::|||||.::||:.|||||....:|||:||.::.:|..:|.:|:.|||
  Rat   131 SLDVRSFFGFESTLEKIAMKQYTANVKRGKEVIEHYLSELISQGASHIPRWTPAPVREADVRSQL 195

  Fly   183 -----------SPSDATKSPTLDQASDQQHSILLDGDFIARSLGQLSPMQESKLLELRKMLDGVD 236
                       .|||| .:|..:.|:.....  ||.|:|.|.||.|||||||.|::||:.|....
  Rat   196 VCPCPSSLETDGPSDA-PAPASEMATADGDK--LDADYIERCLGHLSPMQESCLVQLRRWLQETH 257

  Fly   237 DLERVPSYQTILRFLAARDWHVSQAYAMLCDSLRWRREHRIDALLAEYSKPAVVVEHFPGGWHHL 301
            . .::|..:.|||||.|||:|:.:|..|||.||.||::|::|.||..:..||.:.|.:.||||:.
  Rat   258 K-GKIPKDEHILRFLRARDFHLDKARDMLCQSLSWRKQHQVDLLLQTWRPPAPLQEFYAGGWHYQ 321

  Fly   302 DKDGRPVYILRLGHMDVKGLLKSLGMDGLLRLALHICEEGIQKINESAERLEKPVLNWSLLVDLE 366
            |.||||:||||||.||.|||:|::|.:.||:..|.:.|||.::...:..:..:|:.:|:.|:|||
  Rat   322 DIDGRPLYILRLGQMDTKGLMKAVGEEALLQHVLSVNEEGQKRCEGNTRQFGRPISSWTCLLDLE 386

  Fly   367 GLSMRHLWRPGIKALLNIIETVERNYPETMGRVLVVRAPRVFPIAWTIVSAFIDEHTRSKFLFYG 431
            ||:||||||||:||||.:||.||.|||||:||:|:||||||||:.||:||.||:|:||.|||.|.
  Rat   387 GLNMRHLWRPGVKALLRMIEVVEDNYPETLGRLLIVRAPRVFPVLWTLVSPFINENTRRKFLIYS 451

  Fly   432 PDCAHMKDGLAQYLDEEIVPDFLGGPCKTMIHEGGLVPKTLYKMNSLEDHDDEVTAELPTTAAAQ 496
            ........||..|||::::||||||.....:.|||:|||:||    |.:.:.|
  Rat   452 GSNYQGPGGLVDYLDKDVIPDFLGGESVCNVPEGGMVPKSLY----LTEEEQE------------ 500

  Fly   497 ALVPGKRLSANQQHDHRNLYKSVDLKAGFAHELLIRNEDPKSVLTWDFDVMRNDLHFTLY----- 556
                    .|:|.......|.|..:..|..||:.:...:.:||:|||||::|.|:.|:||
  Rat   501 --------QADQLRQWSETYHSASVLRGSPHEVAMEIPEGESVITWDFDILRGDVVFSLYHAKQA 557

  Fly   557 ----------RVTQELPEKNDSAVSYFDLQDFVEGVNYFREEPTLICRHKESVQGSHVMHHNDSY 611
                      |.:.:|.:||           ::.||:|.|.|..||||..:|:|||||......|
  Rat   558 PKLSPQEPGVRASGQLIDKN-----------WILGVDYSRVEAPLICREGQSIQGSHVTQWPGVY 611

  Fly   612 LMHW--FSP--------------------SGAQLNVFY--EVLSSANYKGSMTSLQSA------F 646
            |:.|  .||                    .|.:..:.|  |||:|.:::|||:||:|.      .
  Rat   612 LLQWQIHSPPESVACSLPGVDDVLTALHSPGPKCKLLYYCEVLASEDFRGSMSSLESCASRFSQL 676

  Fly   647 SSNSSAASSVQS 658
            |:.::::||.||
  Rat   677 SATTTSSSSGQS 688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
retm	NP_001260132.1	PRELI	17..173	CDD:398400	80/155 (52%)
		CRAL_TRIO_N	222..268	CDD:215024	20/45 (44%)
		CRAL_TRIO	293..456	CDD:459890	90/162 (56%)
Sec14l5	NP_001129182.2	PRELI	17..173	CDD:398400	80/155 (52%)
		CRAL_TRIO_N	243..288	CDD:215024	20/45 (44%)
		CRAL_TRIO	314..476	CDD:459890	90/161 (56%)