DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment retm and SPBC365.01

DIOPT Version :9

Sequence 1:	NP_001260132.1	Gene:	retm / 33899	FlyBaseID:	FBgn0031814	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	NP_596030.1	Gene:	SPBC365.01 / 2541046	PomBaseID:	SPBC365.01	Length:	355	Species:	Schizosaccharomyces pombe

Alignment Length:	286	Identity:	75/286 - (26%)
Similarity:	125/286 - (43%)	Gaps:	48/286 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   216 QLSPMQESKLLELRKMLDGVDDLERVPSYQTILRFLAARDWHVSQAYAMLCDSLRWRREHRIDAL 280
            |..|.|||..:...:.. ..||.:     .|:||||.||.:.|:.:..||.:::.||::..:.::
pombe    30 QKFPSQESLYVSFFEQC-AFDDFD-----LTLLRFLKARKFVVTDSSDMLANAIVWRQQANLRSI 88

  Fly   281 LA--------EYSKPAVVVEHFPGGWHHLDKDGRPVYILRLGHMDVKGLLKSLGMDGLLRLALHI 337
            :.        .:.|.::   :|..|   .||.||.:..|.|.:.......|.  |:.|..|.|:.
pombe    89 MVRGENGLNQNFVKASM---YFIWG---QDKKGRAIVFLNLHNFIPPKNTKD--MEELKALILYA 145

  Fly   338 CEEGIQKINESAERLEKPVLNWSLLVDLEGLSMRHLWRPGIKALLNIIETVERNYPETMGRVLVV 402
            .|.. :...:|.:...|.||.   ||||...|.:::   .:.......||.:..|||.:|:.|:|
pombe   146 MENA-RLFLDSEQNAAKGVLG---LVDLTYFSRKNI---DLDFARVFAETFQNYYPEILGQALIV 203

  Fly   403 RA---PRVFPIAWTIVSAFIDEHTRSKFLFYGPDCAHMKDGLAQ---YLDEEIVPDFLGGPC-KT 460
            .:   ..:|...|:|...|:|...|||..|..|         ||   |:|.:.:|..:.|.. :|
pombe   204 GSGFRMALFEGVWSIGKYFLDPEVRSKVTFCKP---------AQVSGYVDSKYIPLSMHGQFDET 259

  Fly   461 MIHEGGLVPKT--LYKMNSLEDHDDE 484
            .::|.. .|:|  :.|..:.|:.|.|
pombe   260 KLYERA-PPETAGIGKPENYEELDKE 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
retm	NP_001260132.1	PRELI	17..173	CDD:282550
		CRAL_TRIO_N	222..268	CDD:215024	14/45 (31%)
		CRAL_TRIO	293..456	CDD:279044	46/168 (27%)
SPBC365.01	NP_596030.1	CRAL_TRIO_N	26..73	CDD:281722	15/48 (31%)
SPBC365.01	NP_596030.1	SEC14	100..257	CDD:214706	48/180 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1304
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940