DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment retm and CG30339

DIOPT Version :9

Sequence 1:	NP_001260132.1	Gene:	retm / 33899	FlyBaseID:	FBgn0031814	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	NP_724813.1	Gene:	CG30339 / 246549	FlyBaseID:	FBgn0050339	Length:	308	Species:	Drosophila melanogaster

Alignment Length:	352	Identity:	70/352 - (19%)
Similarity:	123/352 - (34%)	Gaps:	89/352 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 LGQLSPMQESKLLELRKM----LDGVDDLERVPSYQTILRFLAARDWHVSQAYAMLCDSLRWRRE 274
            :..|.|:.    .|||::    |:.|:  ||||:     ...|.|||...|.:      ||.|::
  Fly     1 MANLRPLS----AELRRIAETELNEVE--ERVPA-----DLKALRDWLAKQPH------LRARQD 48

  Fly   275 HRIDALLAEY--------SKPAVVVEHF-------PGGWHHLDKDGRPVYILRLGHMDVKGLLKS 324
               |..|..:        .|....::||       |..:.....|.|.:.:.|.|  ....|.|.
  Fly    49 ---DQFLVGFLRGCKFSLEKTKSKLDHFYTIKTLMPELFGKRLVDERNLILCRSG--TYVRLPKP 108

  Fly   325 LGMDG--------------------LLRLALHICEEGIQKINES-----AERLEKPVLNWSLLVD 364
            .|.||                    |.|....|.|:.|::.:.|     .|.::...::.|.|..
  Fly   109 WGTDGPRLQLTNYEKFDPKEFKLLDLFRYQTMITEQSIREDDHSNISGYVEIVDMAKMSLSFLAQ 173

  Fly   365 LEGLSMRHLWRPGIKALLNIIETVERNYPETMGRVLVVRAPRVFPIAWTIVSAFIDEHTRSKFLF 429
            |:...::   |.||.|        |:..|..:..|.::..|:.......:..:.:....:.:|..
  Fly   174 LDFTLIK---RMGIFA--------EKAQPTRLKGVHLINCPKEGVALLNLAKSLMPSKLQQRFHV 227

  Fly   430 YGPDCAHMKDGLAQYLDEEIVPDFLGGPCKTMIHEGGLVPKTLYKMNSLEDHDDEVTAELPTTAA 494
            |     ...:.|.:.:..|.:|:..||....:........|.|....|....|.:...:
  Fly   228 Y-----KNLEQLNEVIPREYLPEEYGGNNGRIADIQAEAEKKLLSYESYFAEDSQYGVD------ 281

  Fly   495 AQALVPGKRLSANQQHDHRNLYKSVDL 521
             :.|.||||::|:........::.:|:
  Fly   282 -EQLRPGKRVNADSIFGAEGSFRKLDI 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
retm	NP_001260132.1	PRELI	17..173	CDD:282550
		CRAL_TRIO_N	222..268	CDD:215024	14/49 (29%)
		CRAL_TRIO	293..456	CDD:279044	35/194 (18%)
CG30339	NP_724813.1	CRAL_TRIO_N	28..70	CDD:215024	11/55 (20%)
CG30339	NP_724813.1	CRAL_TRIO	109..250	CDD:279044	27/156 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810