DRSC/TRiP Functional Genomics Resources

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Protein Alignment retm and Sec14l2

DIOPT Version :9

Sequence 1:NP_001260132.1 Gene:retm / 33899 FlyBaseID:FBgn0031814 Length:707 Species:Drosophila melanogaster
Sequence 2:NP_446253.2 Gene:Sec14l2 / 116486 RGDID:621779 Length:403 Species:Rattus norvegicus


Alignment Length:456 Identity:120/456 - (26%)
Similarity:211/456 - (46%) Gaps:88/456 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   214 LGQLSPMQESKLLELRKMLDGVDDLERVPSYQTILRFLAARDWHVSQAYAMLCDSLRWRREHRID 278
            :|.|||.||..|.:.|:.:..|......|....:||:|.||.:.:.::.|||...:.:|::..||
  Rat     5 VGDLSPKQEEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDID 69

  Fly   279 ALLAEYSKPAVVVEHFPGGWHHLDKDGRPVYILRLGHMDVKGLLKSLGMDGLLRLALHICEEGIQ 343
            .::: :..|.|:.::..||....|.||.||:...:|.:|.||||.|.....|||..:..||..:|
  Rat    70 KIIS-WQPPEVIQQYLSGGRCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRDCELLLQ 133

  Fly   344 KINESAERLEKPVLNWSLLVDLEGLSMRHLWRPGIKALLNIIETVERNYPETMGRVLVVRAPRVF 408
            :......:|.|.:...:::.|.|||.::|||:|.::|....:...|.|||||:.|:.||:||::|
  Rat   134 ECTHQTAKLGKKIETITMIYDCEGLGLKHLWKPAVEAYGEFLTMFEENYPETLKRLFVVKAPKLF 198

  Fly   409 PIAWTIVSAFIDEHTRSKFLFYGPDCAHMKDGLAQYLDEEIVPDFLGG---------PCKTMIHE 464
            |:|:.::..|:.|.||.|.:..|   |:.|:.|.:::..:.:|...||         .||:.|:.
  Rat   199 PVAYNLIKPFLSEDTRKKIMVLG---ANWKEVLLKHISPDQLPVEYGGTMTDPDGNPKCKSKINY 260

  Fly   465 GGLVPKTLYKMNSLEDHDDEVTAELPTTAAAQALVPGKRLSANQQHDHRNLYKSVDLKAGFAHEL 529
            ||.:||..|..:.::                            ||::|     ||.:..|.:|::
  Rat   261 GGDIPKQYYVRDQVK----------------------------QQYEH-----SVQISRGSSHQV 292

  Fly   530 LIRNEDPKSVLTWDFDVMRNDLHFTLY------------RVTQELPEKNDSAVSYFDLQDFVEGV 582
            ......|..||.|.|....:|:.|.::            .:|:.||.:..::             
  Rat   293 EYEILFPGCVLRWQFMSEGSDVGFGIFLKTKMGERQRAGEMTEVLPNQRYNS------------- 344

  Fly   583 NYFREEPTLICRHKESVQGSHVMHHNDSY-LMHWFSPSGAQLNVFYEVL-------SSANYKGSM 639
            :...|:.||.|    |..|.:|:..:::| .:|     ..:::...|||       ...|.:|::
  Rat   345 HMVPEDGTLTC----SEPGIYVLRFDNTYSFIH-----AKKVSFTVEVLLPDKAAEEKLNQQGTV 400

  Fly   640 T 640
            |
  Rat   401 T 401

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
retmNP_001260132.1 PRELI 17..173 CDD:282550
CRAL_TRIO_N 222..268 CDD:215024 13/45 (29%)
CRAL_TRIO 293..456 CDD:279044 55/162 (34%)
Sec14l2NP_446253.2 CRAL_TRIO_N 13..59 CDD:215024 13/45 (29%)
SEC14 76..244 CDD:214706 58/170 (34%)
GOLD_2 300..381 CDD:290608 18/102 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166345469
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1471
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1133487at2759
OrthoFinder 1 1.000 - - FOG0000197
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
65.750

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