DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment retm and sec14l3

DIOPT Version :9

Sequence 1:	NP_001260132.1	Gene:	retm / 33899	FlyBaseID:	FBgn0031814	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	NP_001120265.1	Gene:	sec14l3 / 100145318	XenbaseID:	XB-GENE-951877	Length:	410	Species:	Xenopus tropicalis

Alignment Length:	413	Identity:	108/413 - (26%)
Similarity:	199/413 - (48%)	Gaps:	60/413 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 LGQLSPMQESKLLELRKMLDGVDDL-ERVPSYQT----ILRFLAARDWHVSQAYAMLCDSLRWRR 273
            :|.|||.||..|::.|   :.|.|| .|:|.:..    :||:|.||.:::.:|..||..::.:|:
Frog     5 VGDLSPKQEEALVKFR---ENVKDLMPRLPPFSQDDYFLLRWLRARSFNLQKAENMLRKNVEFRK 66

  Fly   274 EHRIDALLAEYSKPAVVVEHFPGGWHHLDKDGRPVYILRLGHMDVKGLLKSLGMDGLLRLALHIC 338
            :...|.:|.::..|.||.::..||....|::..|::...:|.:|.||||.|.....|::..:..|
Frog    67 QMDSDNVLEKWQPPEVVQKYLSGGLCGHDREDSPIWYDVIGPLDPKGLLFSASKQDLMKTKMRDC 131

  Fly   339 EEGIQKINESAERLEKPVLNWSLLVDLEGLSMRHLWRPGIKALLNIIETVERNYPETMGRVLVVR 403
            |.........:|:|.|.|.:..::.|:|||.::|||:|.::....|::..|.||||.:.|:.|::
Frog   132 EVLHHACRMQSEKLGKRVEDVVMIYDVEGLGLKHLWKPAVELYGEILQMFEDNYPEALKRLFVIK 196

  Fly   404 APRVFPIAWTIVSAFIDEHTRSKFLFYGPDCAHMKDGLAQYLDEEIVPDFLGG---------PCK 459
            ||::||:|:.::..|:.|.||.|.:..|.   :.:|.|.:|:..|.:|.:.||         .||
Frog   197 APKLFPVAYNLIKHFLSEDTRRKIMVLGD---NWQDVLKKYIAPEELPQYYGGTLTDPDGDPKCK 258

  Fly   460 TMIHEGGLVPKTLYKMNSLEDHDDEVTAELPTTAAAQALVPGKRLSANQQHDHRNLYKSVDLKAG 524
            :.|:.||.:||..|..:.::                                 :|...::::..|
Frog   259 SKINYGGDIPKKYYVRDQVK---------------------------------QNYENTLNINRG 290

  Fly   525 FAHELLIRNEDPKSVLTWDFDVMRNDLHFTLYRVTQE-LPEKNDSAVSYFDLQDFVEGVNYFREE 588
            .:.::......|..||.|.|.....|:.|.:||.|:. ..:|....|.....|.:  ..:...|:
Frog   291 SSQQMEYEILFPSCVLRWQFQSDGADIGFGIYRKTKAGERQKAGEMVEVLANQRY--NAHMVPED 353

  Fly   589 PTLICRHKESVQGSHVMHHNDSY 611
            .|:.|    :..|::|:..:::|
Frog   354 GTMTC----TEPGTYVLRFDNTY 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
retm	NP_001260132.1	PRELI	17..173	CDD:282550
		CRAL_TRIO_N	222..268	CDD:215024	16/50 (32%)
		CRAL_TRIO	293..456	CDD:279044	50/162 (31%)
sec14l3	NP_001120265.1	CRAL_TRIO_N	13..60	CDD:215024	16/49 (33%)
sec14l3	NP_001120265.1	SEC14	79..248	CDD:214706	55/171 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	1	1.000	-	-		FOG0000197
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1304
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950