DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9527 and ACX3

DIOPT Version :9

Sequence 1:	NP_001137800.1	Gene:	CG9527 / 33898	FlyBaseID:	FBgn0031813	Length:	724	Species:	Drosophila melanogaster
Sequence 2:	NP_172119.1	Gene:	ACX3 / 837140	AraportID:	AT1G06290	Length:	675	Species:	Arabidopsis thaliana

Alignment Length:	667	Identity:	202/667 - (30%)
Similarity:	315/667 - (47%)	Gaps:	79/667 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 EYRERASFCYKRMNVVLEGED--------HIRLKHKVWQWMEQ------HPDYQREPGSDLERTR 106
            |..|...|..|.|..:|:|.:        .:.::..::...|:      .|||.:    .:|:.|
plant    41 ELNESYGFDVKEMRKLLDGHNVVDRDWIYGLMMQSNLFNRKERGGKIFVSPDYNQ----TMEQQR 101

  Fly   107 EMANKR-QHLLWEQQFYGVNEYLGTPHLL--LAFGQAIFSYDFSTSVKFGLSTGMFPSTLVSNGS 168
            |:..|| .:||....|.|.....|....|  ||..:....||.|.|:|.|:...::.:.:...|:
plant   102 EITMKRIWYLLENGVFKGWLTETGPEAELRKLALLEVCGIYDHSVSIKVGVHFFLWGNAVKFFGT 166

  Fly   169 GR-LGKYVAKIADNRILGAYALTEISHGTNALGMRTRATYDVKRQEFIIHTPDFEAAKCWVGNLG 232
            .| ..|::....|..:.|.:|:||:.||:|..|:.|..|||.|.:||:|:||...|.|.|:|...
plant   167 KRHHEKWLKNTEDYVVKGCFAMTELGHGSNVRGIETVTTYDPKTEEFVINTPCESAQKYWIGGAA 231

  Fly   233 KTCTHAIVYAQLYVPDDKHQGLQAFLVPIRDERTLLPFPGVTVGDMGEKIGLNGIDNGFVMFNQY 297
            ...||.||::||:: :..:||:.||:..|||:...: .|.:.:.|.|.||||||:|||.:.|:..
plant   232 NHATHTIVFSQLHI-NGTNQGVHAFIAQIRDQDGSI-CPNIRIADCGHKIGLNGVDNGRIWFDNL 294

  Fly   298 RIPKANLLSKTGDIDAQGNYTSKIKDERKRLGASLGALSVGRVNITAITYVALSKAVTIATRYAA 362
            |||:.|||:...|:.:.|.|.|.|||..:|.||.:..|:.|||.|.:....:....::||.||:.
plant   295 RIPRENLLNAVADVSSDGKYVSSIKDPDQRFGAFMAPLTSGRVTIASSAIYSAKVGLSIAIRYSL 359

  Fly   363 SRRQFGPTNSPAEWPVIEYQSQQYRLIPHLATTIALRVATLWIGKENVDLTMKGFTGEDTSQAGM 427
            |||.|..|.:..|..:::|.|.|.||:|.||.|.|:..|.         ..:|....:.|.:...
plant   360 SRRAFSVTANGPEVLLLDYPSHQRRLLPLLAKTYAMSFAA---------NELKMIYVKRTPETNK 415

  Fly   428 EIHAISSALKPVATWAARDGIQECREACGGHGYLKSSGLGELRNDNDANCTYEGENNTLIQQASN 492
            .||.:||..|.|.||.....:||||||.||.|....:.:|:|:.:.|...|:||:||.|:||.|.
plant   416 AIHVVSSGFKAVLTWHNMHTLQECREAVGGQGVKTENLVGQLKGEFDVQTTFEGDNNVLMQQVSK 480

  Fly   493 WL----ISLQRNNADFVAVSPLETVSFLKDMDTILQSKGQERTPAEVLDPLNLLNALNWLTVWQL 553
            .|    :|.::.|..|..:.       |:.|:          :|..|| |..|.::.  |...|.
plant   481 ALFAEYVSCKKRNKPFKGLG-------LEHMN----------SPRPVL-PTQLTSST--LRCSQF 525

  Fly   554 DTTVKRVEEQ-----------QREGKDAFETRNNIQVFA---AQKLSIIYGERTIYYVFYKFVIG 604
            .|.|..:.|:           |.:|:.  |:|....:.:   |:.|...:.|:.|..........
plant   526 QTNVFCLRERDLLEQFTSEVAQLQGRG--ESREFSFLLSHQLAEDLGKAFTEKAILQTILDAEAK 588

  Fly   605 LPDSAEKKVLQQVLSFYGAHLVTKYSAAFYRGGYF-RENSNQLELYEQGILALLPLLKNEAIALV 668
            ||..:.|.||..|.|.| |.:..:...:..|.||. ::|...:   .:.:..|...|:..|:|||
plant   589 LPTGSVKDVLGLVRSMY-ALISLEEDPSLLRYGYLSQDNVGDV---RREVSKLCGELRPHALALV 649

  Fly   669 DAIAPTDFILNSPLGMS 685
            .:....|..| ||:..:
plant   650 TSFGIPDSFL-SPIAFN 665

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9527	NP_001137800.1	ACAD	52..694	CDD:299127	202/667 (30%)
CG9527	NP_001137800.1	PLN02312	56..682	CDD:215178	201/662 (30%)
ACX3	NP_172119.1	PLN02312	1..675	CDD:215178	202/667 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H37792
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D226134at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1055
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10909
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2665
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.880