DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9527 and acox-1.3

DIOPT Version :9

Sequence 1:	NP_001137800.1	Gene:	CG9527 / 33898	FlyBaseID:	FBgn0031813	Length:	724	Species:	Drosophila melanogaster
Sequence 2:	NP_493263.1	Gene:	acox-1.3 / 184167	WormBaseID:	WBGene00008566	Length:	660	Species:	Caenorhabditis elegans

Alignment Length:	693	Identity:	204/693 - (29%)
Similarity:	320/693 - (46%)	Gaps:	112/693 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 LEEYRERASFCYKRMNVVLEGEDHIRLKHKVWQWMEQ----HPDYQREPGSDLERTREMANKRQH 114
            |.|.|:.|:|...:|..|:.|.:.|..:.:  |..|.    |...:.:|...:.|..::|...:.
Worm    12 LTEERKNATFDTDKMAAVIYGREEIASRRR--QLTESISRIHELAESKPLVFMTREEKIAESCRK 74

  Fly   115 L-----LWEQQFYG----------VNEYLGTPHLLLAFGQAIFSYDFSTSVKFGLSTGMFPSTLV 164
            |     .|.|..:.          ..|.||.....||                 |...||..|||
Worm    75 LEVLSRHWNQTPFNRDNEEDALHIYREVLGMEGHPLA-----------------LHDTMFIPTLV 122

  Fly   165 SNGS-GRLGKYVAKIADNRILGAYALTEISHGTNALGMRTRATYDVKRQEFIIHTPDFEAAKCWV 228
            :..| .:..|::.:.....|:|.||.||:.||||...:.|.|||....||||::||...|.|.|.
Worm   123 AQASQEQQEKWLGRARRKEIIGCYAQTEMGHGTNLRKLETTATYSPDTQEFILNTPTITALKWWP 187

  Fly   229 GNLGKTCTHAIVYAQLYVPDDKHQGLQAFLVPIRDERTLLPFPGVTVGDMGEKIGLNGIDNGFVM 293
            |.|||:..:|||.|.|.:.|..: |...|:|.:|||:|.:|..|:.|||:|.|:..||.|||::.
Worm   188 GALGKSSNNAIVVANLLIKDQNY-GPHPFMVQLRDEKTHIPLKGIVVGDIGPKMAFNGADNGYLG 251

  Fly   294 FNQYRIPKANLLSKTGDIDAQGNYTSKIKDERKRLGASLGALSVGRVNITAITYVALSKAVTIAT 358
            ||.:|||:.|||.:...::|.|.|   ||....::|.|  ::...|..:.....:.|:.|:.||.
Worm   252 FNNHRIPRTNLLMRHTKVEANGTY---IKPSHAKIGYS--SMVKVRSRMAMDQGLFLASALVIAV 311

  Fly   359 RYAASRRQFGPTNSPAEWPVIEYQSQQYRLIPHLATTIALRVATLWIGKENVDL---TMKGFTGE 420
            ||:|.|||....:...:..|::||:||:||.|.||...|.    ::.|.|.:.|   .:|.....
Worm   312 RYSAVRRQGFLEDKTQKVKVLDYQTQQHRLFPSLARAYAF----IFTGFETIHLYSQLLKDVDMG 372

  Fly   421 DTSQAGM-EIHAISSALKPVATWAARDGIQECREACGGHGYLKSSGLGELRNDNDANCTYEGENN 484
            :||  || ::||::|.||.|.|....:||::.|.|||.|||..:|.:.|:.......|||||||.
Worm   373 NTS--GMADLHALTSGLKSVVTHQTGEGIEQARMACGEHGYSMASYISEIYGVAIGGCTYEGENM 435

  Fly   485 TLIQQASNWLISLQRNNADFVAVSPLETVSFLKD--------MDTILQSKGQERTPAEVLDPLNL 541
            .::.|.:.:|:               ::|..:|.        |.:.|.:||....
Worm   436 VMLLQLARYLV---------------KSVELIKSGEEKKLGPMVSYLAAKGGHPD---------- 475

  Fly   542 LNALN-WLT---------VWQLDTTVKRVEEQQREGKDAFETRNNIQVFAAQKLSIIYGERTIYY 596
            |::|| ::|         .|:......::.| ..|.::....::.:::..|.:|   :....|..
Worm   476 LSSLNGYVTAFEHMARRQAWKATEKFLKLME-TGESREVAWNKSAVELTRASRL---HTRLFIIE 536

  Fly   597 VFYKFVIGLPDSAEKKVLQQVLSFYGAHLVTKY---SAAFYRGGYFRENSNQLELYEQGILALLP 658
            .|.:.|..:.|...|:||..:|     ||...|   ..|.|...:.  :|.||:.....:...|.
Worm   537 AFMRRVSRIEDIPVKEVLTDLL-----HLHVNYELLDVATYALEFM--SSTQLDYIRDQLYLYLE 594

  Fly   659 LLKNEAIALVDAIAPTDFILNSPLGMSDGNVYQHLQRTLVSTP 701
            .::..|::|||:...:|..|.|.||..|||||::|.:...|:|
Worm   595 KIRPSAVSLVDSFQISDMQLRSVLGRRDGNVYENLFKWAKSSP 637

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9527	NP_001137800.1	ACAD	52..694	CDD:299127	201/684 (29%)
CG9527	NP_001137800.1	PLN02312	56..682	CDD:215178	193/670 (29%)
acox-1.3	NP_493263.1	ACAD	11..634	CDD:299127	202/688 (29%)
acox-1.3	NP_493263.1	PLN02443	12..657	CDD:178062	204/693 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810