DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9527 and acox-1.4

DIOPT Version :9

Sequence 1:	NP_001137800.1	Gene:	CG9527 / 33898	FlyBaseID:	FBgn0031813	Length:	724	Species:	Drosophila melanogaster
Sequence 2:	NP_493264.1	Gene:	acox-1.4 / 173164	WormBaseID:	WBGene00008567	Length:	662	Species:	Caenorhabditis elegans

Alignment Length:	698	Identity:	204/698 - (29%)
Similarity:	325/698 - (46%)	Gaps:	114/698 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 PDFRSGPLEEYRERASFCYKRMNVVLEGEDHI-RLKHKVWQWMEQHP---DYQREPGSD-LERTR 106
            ||     |.|.||:.:|...:|..|:.|.:.: |.:.::.:.:.:.|   |.|..|..| ||:..
Worm    13 PD-----LTEEREKGTFDTDKMAAVIYGSEKLARRRREISEAVSKIPELADTQPFPFMDRLEKIT 72

  Fly   107 EMANKRQHLLWEQQFYGVNEYLGTPHLLLAFGQAIFSYDFSTSVK---FGLSTGMFPSTLVSNGS 168
            |.:.|.:.|  ......:.:|...       |:.:..|...|.::   ..|...||...|||..|
Worm    73 EGSRKLEVL--NNNIRDIIDYDDN-------GERLHIYQEVTGMEGHPLALHEVMFIPALVSQAS 128

  Fly   169 -GRLGKYVAKIADNRILGAYALTEISHGTNALGMRTRATYDVKRQEFIIHTPDFEAAKCWVGNLG 232
             .:..|::.:.....|:|.||.||:.||||...:.|.|||....|||:::||...|.|.|.|.||
Worm   129 KEQQEKWLGRARRREIIGCYAQTEMGHGTNLRKLETTATYFPDTQEFVLNTPTTTALKWWPGALG 193

  Fly   233 KTCTHAIVYAQLYVPDDKHQGLQAFLVPIRDERTLLPFPGVTVGDMGEKIGLNGIDNGFVMFNQY 297
            |:..:|:|...:.: ..|..|...|:|.:|||:|.:|..|:.|||:|.|:..||.||||:.|:::
Worm   194 KSSNYAVVVVDMII-KGKSYGPHPFMVQLRDEKTHIPLKGIVVGDIGPKMSFNGGDNGFLGFDKF 257

  Fly   298 RIPKANLLSKTGDIDAQGNYT---------SKIKDERKRLGASLGALSVGRVNITAITYVALSKA 353
            |:|:.|||.:...::|.|.|.         |.:...|..:....|||              |::|
Worm   258 RVPRTNLLMRHVRVEADGTYVKPPHAKVNHSAMVHVRSHMATGQGAL--------------LAQA 308

  Fly   354 VTIATRYAASRRQFGPTNSPAEWPVIEYQSQQYRLIPHLATTIALRVATLWIGKENVDL---TMK 415
            :.||.||:|.|||....|...|..|::||:||:||.|.||...|.    ::.|.|.:.|   .:|
Worm   309 LIIAVRYSAVRRQGFLENKTQEVKVLDYQTQQHRLFPSLARAYAF----IFTGFETIHLYSQLLK 369

  Fly   416 GFTGEDTSQAGM-EIHAISSALKPVATWAARDGIQECREACGGHGYLKSSGLGELRNDNDANCTY 479
            .....:||  || ::||::|.||.|.|....:||::.|.|||||||..:|.:.|:.......|||
Worm   370 DVDMGNTS--GMADLHALTSGLKSVVTHQTGEGIEQARMACGGHGYSMASYISEIYGIAIGGCTY 432

  Fly   480 EGENNTLIQQASNWLISLQRNNADFVAVSPLETVSFLKD--------MDTILQSKGQERTPAEVL 536
            ||||..::.|.:.:|:               ::|..:|.        |.:.|.:||....
Worm   433 EGENMVMLLQLARYLV---------------KSVELIKSGEAKKLGPMVSYLAAKGGHPD----- 477

  Fly   537 DPLNLLNALN-WLT---------VWQLDTTVKRVEEQQREGKDAFETRNNIQVFAAQKLSIIYGE 591
                 |::|| ::|         .|:......::.| ..|.::....::.:::..|.:|   :..
Worm   478 -----LSSLNGYVTAFEHMARRQAWKATEKFLKLME-SGESREIAWNKSTVELTRASRL---HTR 533

  Fly   592 RTIYYVFYKFVIGLPDSAEKKVLQQVLSFYGAHLVTKY---SAAFYRGGYFRENSNQLELYEQGI 653
            ..|...|.:.|..:.|...|:||..:|     ||...|   ..|.|...:.  :|.||:.....:
Worm   534 LFIIEAFMRRVSRIEDIPVKEVLTDLL-----HLHVNYELLDVATYALEFM--SSTQLDYIRDQL 591

  Fly   654 LALLPLLKNEAIALVDAIAPTDFILNSPLGMSDGNVYQHLQRTLVSTP 701
            ...|..::..|::|||:...:|..|.|.||..|||||::|.:...|:|
Worm   592 YLYLEKIRPSAVSLVDSFQISDMQLRSVLGRRDGNVYENLFKWAKSSP 639

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9527	NP_001137800.1	ACAD	52..694	CDD:299127	199/684 (29%)
CG9527	NP_001137800.1	PLN02312	56..682	CDD:215178	191/668 (29%)
acox-1.4	NP_493264.1	PLN02443	9..659	CDD:178062	204/698 (29%)
acox-1.4	NP_493264.1	ACAD	13..636	CDD:299127	202/693 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D226134at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820