DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9527 and Acadvl

DIOPT Version :9

Sequence 1:	NP_001137800.1	Gene:	CG9527 / 33898	FlyBaseID:	FBgn0031813	Length:	724	Species:	Drosophila melanogaster
Sequence 2:	NP_059062.1	Gene:	Acadvl / 11370	MGIID:	895149	Length:	656	Species:	Mus musculus

Alignment Length:	367	Identity:	85/367 - (23%)
Similarity:	149/367 - (40%)	Gaps:	66/367 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 TPHLLLAFGQAIFSYDFSTSVKFGLSTGM-FPSTLVSNGSGRLGKYVAKIADNRILGAYALTEIS 193
            |.:..||  :.:..:|...||..|....: |...|:.....:..||:.::|..:.|.|:.|||.|
Mouse   159 TQYARLA--EIVGMHDLGVSVTLGAHQSIGFKGILLYGTKAQREKYLPRVASGQALAAFCLTEPS 221

  Fly   194 HGTNALGMRTRATYDVKRQEFIIHTP-----DFEAAKCWVGNLGKTCTHAIVYAQLYVPDDK--- 250
            .|::...:|:.|          |.:|     ....:|.|:.| |.......|:|:..:.|..
Mouse   222 SGSDVASIRSSA----------IPSPCGKYYTLNGSKIWISN-GGLADIFTVFAKTPIKDAATGA 275

  Fly   251 -HQGLQAFLVPIRDERTLLPFPGVTVGDMGEKIGLNGIDNGFVMFNQYRIPKANLLSKTGDIDAQ 314
             .:.:.||:|    ||:   |.|||.|...:|:|:...:...|.|:..::|..|:|.:.||
Mouse   276 VKEKITAFVV----ERS---FGGVTHGLPEKKMGIKASNTSEVYFDGVKVPSENVLGEVGD---- 329

  Fly   315 GNYTSKIKDERKRLGASLGALSVGRVNITAITYVALSKAVTIATRYAASRRQFGPTNSPAEWPVI 379
                        ....::..|:.||..:.|.....:...:..|..:|.:|.|||  :....:.||
Mouse   330 ------------GFKVAVNILNNGRFGMAATLAGTMKSLIAKAVDHATNRTQFG--DKIHNFGVI 380

  Fly   380 EYQSQQYRLIPHLATTIALRVATLWIGKENVDLTMKGFTGEDTSQAGMEIHAISSALKPVATWAA 444
            :.:..:..::.::..::|..::.      |:|...|.|..|         .|||......|.|..
Mouse   381 QEKLARMAILQYVTESMAYMLSA------NMDQGFKDFQIE---------AAISKIFCSEAAWKV 430

  Fly   445 RDGIQECREACGGHGYLKSSGLGELRNDNDANCTYEGENNTL 486
            .|   ||.:..||.|::|..|:..:..|......:||.|:.|
Mouse   431 AD---ECIQIMGGMGFMKEPGVERVLRDIRIFRIFEGANDIL 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9527	NP_001137800.1	ACAD	52..694	CDD:299127	85/367 (23%)
CG9527	NP_001137800.1	PLN02312	56..682	CDD:215178	85/367 (23%)
Acadvl	NP_059062.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..33
		Catalytic. /evidence=ECO:0000250\|UniProtKB:P49748	42..483		85/367 (23%)
		VLCAD	73..482	CDD:173850	85/367 (23%)
		CaiA	95..474	CDD:224871	85/367 (23%)
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:P49748	462..464		0/1 (0%)
		Membrane-anchoring. /evidence=ECO:0000250\|UniProtKB:P49748	484..517
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810