Protein Alignment Nepl6 and Ecel1

DIOPT Version :10

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_063123735.1
• Gene: Ecel1 / 60417
• RGDID: 61806
• Length: 792
• Species: Rattus norvegicus
• Alignment Length: 754
• Identity: 167/754 - (22%)
• Similarity: 286/754 - (37%)
• Gaps: 180/754 - (23%)

  Fly     3 LIACLFIVPICAAPTTQNVEADPNSRLMNNILSYVAEDSSA----CGTYFQYACGKYAVRHR--D 61
            ::|..::.|..|.......|..|..:.......:::.:..|    |..::.:|||.:..||.  |
  Rat    79 MLALKYLGPGAAGTGGACPEGCPERKAFARAARFLSANLDASIDPCQDFYSFACGGWLRRHAIPD 143

  Fly    62 DPFT-EIIQMLDHKVNGNLVQLMHELHQRSQSPGFNESSVEAKVLHFYRTCREAPPSTRKMEHYL 125
            |..| ..|..:..:   |..:|...|.:.:..||   .:.:.||..|:|:|.:    .|::|
  Rat   144 DKLTYGTIAAIGEQ---NEERLRRLLARPTGGPG---GAAQRKVRAFFRSCLD----MREIE--- 195

  Fly   126 RLAP----------PGQALTWPQFMPRGEPWP------KAQFKWMKSLGHLYRYGFTNVLVNVLV 174
            ||.|          .|..|......|....|.      |||..:..:           .|.::.|
  Rat   196 RLGPRPMLEVIEDCGGWDLGGAADRPGAARWDLNRLLYKAQGVYSAA-----------ALFSLTV 249

  Fly   175 LRSSENSNRF--RLD---ISMPSL-------EGDAQHLGG---FLSTLATLQIIGV-----PTKS 219
            .....||:|:  |:|   :::|..       |...:.|..   |:..|  |:::|.     ..:.
  Rat   250 SLDDRNSSRYVIRIDQDGLTLPERTLYLAQDEESEKVLAAYKVFMERL--LRLLGADAVEQKAQE 312

  Fly   220 ILPLVRKIRRLESAIRVLTEVDD--DDESETW---TLRQWEYKTGY-AWQGFVESIVGHSVSHHY 278
            ||.|.:::..:.     ::|.||  .|.|..:   ||.|.:..|.: .|:..::.|.....|...
  Rat   313 ILQLEQRLANIS-----VSEYDDLRRDVSSVYNKVTLGQLQKITPHLQWKWLLDQIFQEDFSEEE 372

  Fly   279 VMQAQNAKYFTGLKRLMDSTDAEVVANYIMTRFVLYLIDDFIDSNEHID---------------- 327
            .:......|...:.:|:.||...::.||::.|.|:.|       :||:.
  Rat   373 EVVLLATDYMQQVSQLIRSTPRRILHNYLVWRVVVVL-------SEHLSPPFREALHELAKEMEG 430

  Fly   328 ----------CVTDMRRNMNLASNLLY-KERF--LDPATLQQYTQEVTKVFEQLRRQFLLQINEN 379
                      |:....|:..:|...|: .|.|  ...|.:||..:::        :..|.|..|.
  Rat   431 NDKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAKVQQLVEDI--------KYILGQRLEE 487

  Fly   380 RLGLTSEQNSMVATKAQHVVLNIGNLPRGRDHRSF------VSRHYEDLVFPLPDFDYAREHLNL 438
            ...:.::..:....|.|::::.:|       :..|      |.:.||   |.:.:..|.:..||.
  Rat   488 LDWMDAQTKAAARAKLQYMMVMVG-------YPDFLLKPEAVDKEYE---FEVHEKTYFKNILNS 542

  Fly   439 LEFRTRKQVLQLNQSAPTPDEFFYLSDPKTAMSSGPYYLMRLNIIVVPHGLLQEPFFAADSHDIF 503
            :.|..:..|.::.|..   |:..:|..|: |:::  |||...|.:|.|.|:||...:..|.....
  Rat   543 IRFSIQLSVKKIRQEV---DKSTWLLPPQ-ALNA--YYLPNKNQMVFPAGILQPTLYDPDFPQSL 601

  Fly   504 KYSLLGFVLAHELMHSVDTVGLYYDRYGNIHEIGPQISSSPRFVAGLQCLNR---NSTQY----- 560
            .|..:|.::.|||.|..|..|..|||.||:.....:.|.| ||:...:|:.|   |.|.|
  Rat   602 NYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHWWTEASYS-RFLHKAECIVRLYDNFTVYNQRVN 665

  Fly   561 ----LDERIADIAGLDLAYSTYFQNSSQMSLTDFTTIPP--------QQIFFLNLAQFFCGDGDP 613
                |.|.|||:.||.|||..|     |..:.:.....|        .|:||:..||.:|
  Rat   666 GKHTLGENIADMGGLKLAYYAY-----QKWVREHGPEHPLHRLKYTHNQLFFIAFAQNWC----- 720

  Fly   614 INFVGHDNDETRLQQMLNGFAPFHEAFGCPAKSNQPEKC 652
               :...:....||.:.:..||.|..:.|......|..|
  Rat   721 ---IKRRSQSIYLQVLTDKHAPEHYRYACLPSWAVPSLC 756

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	47..653	CDD:341056	160/706 (23%)
Ecel1	XP_063123735.1	None