Protein Alignment Nepl6 and Nepl18

DIOPT Version :10

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Alignment Length: 753
• Identity: 166/753 - (22%)
• Similarity: 300/753 - (39%)
• Gaps: 175/753 - (23%)

  Fly     1 MWLIACLFIVPICAAPT------TQNVEADPNSRLMNNILSYVAE-------DSSACGTYFQYAC 52
            :||...:.|||..|.|:      ..::.:|...:::  :.:.|||       :.|.|..::.:||
  Fly     7 LWLCLLVAIVPAMAKPSDAGDPFADDLTSDYAKKII--VQAKVAEMKTMMKPEVSPCDDFYTHAC 69

  Fly    53 GKYAVRHRDDPFTEIIQMLDHKVNGNLVQLMHELHQRSQSPGFN------------ESSVEAKVL 105
            |.:   ||.:|    .|:|...:..|...:         |.||:            :|.:|.|:.
  Fly    70 GNW---HRHNP----AQLLGDVMTDNFKLI---------SKGFDRRLQRLLRANDLQSELEKKMQ 118

  Fly   106 HFYRTC----REAPPSTRKMEHYLRLAPPGQALTWPQFMPRGEPWPKAQFKWMKSLGHL-YRYGF 165
            .||.:|    |:.......:|:.:|     :..|.|..:  |..|..:.|.|.:::..: ::||
  Fly   119 RFYMSCNLVHRDDVHYKLALENVIR-----EYGTLPALV--GAQWNSSDFSWWRTVAQIQHKYG- 175

  Fly   166 TNVLVNVLVLRSSENSNRFRLDISMPSLEG----------------DAQHLGGFLSTLATLQIIG 214
            ..:::.:.::....|::..|:.||.|..:.                |.|...|..|::|
  Fly   176 KQIIIGLEIMHDIRNTSVNRVYISQPDFKTINTRLTNLMEEVRTSMDLQQYFGLSSSVA------ 234

  Fly   215 VPTKSILPLVRKIRR-----------LESAIRVLTEVDDDDESETWTLRQWEYKTGYAWQGFVES 268
               |.....:.::.|           |:.::.:.|..|          .|.:|.....:..|:..
  Fly   235 ---KHTAEQLTELERTFSSGGSGAATLQESLSLYTVAD----------LQEKYSDHLNFTEFLGL 286

  Fly   269 IVGHS--VSHHYVMQAQNAKYFTGLKRLMDSTDAEVVANYIMTRFVLYLIDDFIDSNEHID---- 327
            |:|..  ....|:   .:.:|.......|.||.....|||::.:    |::||:...:..|
  Fly   287 ILGEENIPKSLYI---YDEEYLDKALLTMRSTPLATQANYVLWK----LLEDFLVDAQPKDMVKW 344

  Fly   328 CVTDMRRNM-NLASNLLYKERFLDPATLQQYTQEVTKVFEQLRRQFLLQINENRLG-LTSEQNSM 390
            |....::.. .||.:.:|| |:.:|    ....||.|:::|::..|..::..::|. :::...::
  Fly   345 CTESTKKYFGKLAEHAVYK-RYRNP----DVESEVHKIWDQIKGIFRQRLLGDKLDWISNATRTL 404

  Fly   391 VATKAQHVVLNIGNLPRGRDHRSFVSRHYEDLVFPLPDFDYAREHLNLLEFRTRKQVLQLNQSAP 455
            ...|.:.:.|||.:.    |..:|.:.:.|  || :...:|......||..:..:.|.::||.|.
  Fly   405 AIEKLERMHLNINSY----DEENFENVYGE--VF-IDRLNYVSNVQQLLIAKGIRFVARINQPAD 462

  Fly   456 TPDEFFYLSDPKTAMSSGPYYLMRLNIIVVPHGLLQEPFFAADSH-DIFKYSLLGFVLAHELMHS 519
            :       .|....:...|.|.::.|.|.:|..|||..:|..|.: :..||:.||::||||::|.
  Fly   463 S-------VDATELLGFTPAYNIQENNITIPVALLQPRYFWGDQYPEALKYATLGYLLAHEMLHG 520

  Fly   520 VDTVGLYYDRYGNIHEIGP--QISSSPRFVAGLQCLNRNSTQY------------LDERIADIAG 570
            .|..|..||..||   :.|  .:.|...|....:|......:|            ..|.|||..|
  Fly   521 FDDDGRQYDASGN---LAPWWDLKSRYEFEERRKCFQAQYHEYQYGGSKLPESKDQSENIADSGG 582

  Fly   571 LDLAYSTY-----FQNSSQMSLTDFTTIP--PQQIFFLNLAQFFCGDGDPINFV---------GH 619
            |.|||:.|     .|:...:.......:|  .:|:|||..||..|   |.:.|:         .|
  Fly   583 LKLAYAAYELWLGQQSEEVLQRETMEGLPFNSRQLFFLGYAQLLC---DDVQFLFQPWVSQSDRH 644

  Fly   620 DNDETRLQQMLNGFAPFHEAFGCPAKS-NQPE-KCQLW 655
            ...:.|:...|:.|..|...|.|...: ..|| ||.::
  Fly   645 APSKYRVIGPLSNFQEFPWVFNCSQSAPMDPEYKCAIY 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	47..653	CDD:341056	152/690 (22%)
Nepl18	NP_651643.1	M13	58..679	CDD:341056	153/695 (22%)