Protein Alignment Nepl6 and Nepl17

DIOPT Version :10

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Alignment Length: 752
• Identity: 178/752 - (23%)
• Similarity: 294/752 - (39%)
• Gaps: 179/752 - (23%)

  Fly     5 ACLFIVPIC--------------AAPTTQNVEADPNSRLMNNILSYVAEDSSACGTYFQYACGKY 55
            |||..|.:.              ..|..|.:.....|..|   .|::....|.|..::.||||.|
  Fly     8 ACLIFVTLAVGSLAIQGGVFKELTTPLGQQIMRIAKSAEM---CSFMDTSVSPCDDFYGYACGNY 69

  Fly    56 AVRHRDDPFTEIIQMLDHKVNGNLVQLMHELHQRSQSPGFNESSV------EAKVLHFYRTCRE- 113
            |.          |.....:.:.|:.|||...:.|......||..:      |.:|.:||.:|.:
  Fly    70 AT----------INAATSQKDTNIRQLMFANYLRRVRQVLNEPRISTDRPMEVRVKYFYESCLDT 124

  Fly   114 APPSTRKMEHYLRLAPPGQALTWPQF--MP--RGEPWPKAQFKWMKSLGHLY-RYGFTNVLVNVL 173
            |...|::..|.|.:.        .:|  ||  .|:.|....|..::.:..|. ||| ...|:.|.
  Fly   125 AALRTKQRSHLLSVL--------REFGGMPAVEGKSWDYVGFDAIEMMAQLLRRYG-KLTLLGVY 180

  Fly   174 VLRSSENS--NRFRLDISMPSLEGD--------------AQHLGGFLSTLA---TLQIIGVPTKS 219
            |:....||  .|.:|...:...|.|              .::|.|....||   ..:||.:.
  Fly   181 VVPDHFNSQIKRLQLGQRLDLAESDEFASLWKKYALKMRLRNLLGLSEELARKTAEEIIELE--- 242

  Fly   220 ILPLVR-----KIRRLESAIRVLTEVDDDDESETWTLRQWEYKTGYAWQGFVESI-VGHSVSHHY 278
             |.|.|     ::.|....:|.||.:.:..::....|....:.|  :|.|...:: |..||
  Fly   243 -LELSRSAFDHRMNRDPRLMRHLTMLSNMSDAYGPILNVTRFVT--SWLGSEYNLPVFESV---- 300

  Fly   279 VMQAQNAKYFTGLKRLMDSTDAEVVANYIMTRFVLYLIDDF-IDSNEH---IDC---VTDMRRNM 336
                  ..|...:|:::.||...|||||:::.    |:.|| |.:||.   :.|   :|::  ..
  Fly   301 ------PSYLFQVKKILLSTPNHVVANYMLSS----LLTDFEITANEEQQKVICHERITEL--FP 353

  Fly   337 NLASNLLYKERFLDPATLQQ----YTQEVTKVFEQLRRQFLLQIN---------ENRLGLTSEQN 388
            ::..:::|.       :|:|    ...|:..::.:|:..|...::         :.|..|..:.|
  Fly   354 DVVDHMVYH-------SLEQQNPYIANEMRSLWVELKSSFREMLSSPDIEWLEKQTREELLEKLN 411

  Fly   389 SMVATKAQHVVLNIGNLPRGRDHRSFVSRHYEDLVFPLPDFDYAREHLNLLEFRTRKQVLQLNQS 453
            .|....|....:|.             ...:.|||  :...||......|||.:.|  :|:.:..
  Fly   412 GMSFEIAGGQAVNF-------------EEQFGDLV--VSSADYYGNIQRLLEVKAR--ILRTDLL 459

  Fly   454 APTPDEFFYLSDPKTAMSSGPYYLMRLNIIVVPHGLLQEPFFAADSHD-IFKYSLLGFVLAHELM 517
            ..:...::|     ..:::.|.|....|::|:|...:|..:...|.:. ..||..|||.:|||:.
  Fly   460 RESSSVYYY-----HGVTATPIYETETNLVVLPVSYMQHRYLWDDIYPAALKYGTLGFTMAHEMA 519

  Fly   518 HSVDTVGLYYDRYGNIHE----------------IGPQISSSPRFVAGLQCLNRNSTQYLDERIA 566
            |..|.:...||..||:::                :..|.|.   .:.|...|.|..:|  .|.||
  Fly   520 HGFDDLNRLYDSRGNLNDNWSTQTKVGFELVKNCLADQFSG---MLYGNLRLRRLKSQ--AESIA 579

  Fly   567 DIAGLDLAYSTYFQNSSQMSLTDFTTIP-----PQQIFFLNLAQFFCGDGDP---INFVG---HD 620
            |..|:.:|.|.|::...|:.:.:..::|     |:|:|||:.|||.|.|..|   .|||.   |.
  Fly   580 DNVGIRIAQSAYWKWLDQVEMEETESLPHMTQSPEQLFFLSAAQFMCSDIYPERRANFVRNNFHP 644

  Fly   621 NDETRLQQMLNGFAPFHEAFGC--PAKSNQPEKCQLW 655
            ..|.|:..|:.....|.|||.|  .:|.|.|.||.::
  Fly   645 PYEARVFAMMINSPAFAEAFQCSNSSKMNPPNKCLMY 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	47..653	CDD:341056	166/692 (24%)
Nepl17	NP_651641.1	M13	55..678	CDD:341056	167/697 (24%)