Protein Alignment Nepl6 and Nep5

DIOPT Version :10

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Alignment Length: 798
• Identity: 145/798 - (18%)
• Similarity: 278/798 - (34%)
• Gaps: 222/798 - (27%)

  Fly    28 RLMNNILSYVAEDSSACGTYFQYACGKYAVRH-RDDPFTEIIQMLDHKVNGNLVQLMHELHQRSQ 91
            |...:::..:.|.:..|..::|:.||::|..| |.|..|......:.:  .::::::.|..:.:.
  Fly   137 RTAASLIYAMDEQTDPCEDFYQFTCGRWANEHPRPDSVTSNDWFRERQ--AHIMRVVREFLRSNI 199

  Fly    92 SPGFNESSVEAKVLHFYRTC--------REAPPSTRKMEHY-LRLAPPGQALTWPQFMPRGEPWP 147
            :....|:..:||.:  ||.|        |:..|....:..: |.:.|....||............
  Fly   200 TKSEPEAVGKAKTM--YRACMDTKLLDKRDLEPLINYLLRFGLPVLPSALNLTLGSGSKYATEAA 262

  Fly   148 KAQFKWMKSLGHLYRY-------GFT------NVLVNVLVLRSSENSNRFRLDISMPSLEGDAQH 199
            ..::.|::|:..:.::       ||.      |..:|.:.|.:.|..:.|       ....|..|
  Fly   263 NVKYNWLQSIVSIKQHLTMDLIIGFDVFPDPFNRTINRIALGTPETDSAF-------PFNNDDSH 320

  Fly   200 LGGFLSTLATLQIIGVPTKSILPLVRKIRRLESAIRVLTEVDDDDESETWTLRQWEYK------- 257
                                  .::|||.|     :.:...:.|||.::...|:.|.:
  Fly   321 ----------------------KMLRKIHR-----KTIFMQNSDDEDDSEDDRESEEEEAAKQTS 358

  Fly   258 TGY-AWQGFVESIV--------------------------GHSVS---HHYVMQAQNAK------ 286
            ||. |:..:|..::                          |..|:   |.:..:|:|..
  Fly   359 TGMTAYLHYVRKVIEKYLLYVDPNVNQEEATLGITELVKQGVRVARKVHEFKEEAENMTKPSKNP 423

  Fly   287 -----YFTGLKRLMDSTDAEVVANY--IMTRFVLYLIDDF-----IDSNEHIDCVT---DMRRNM 336
                 |.| |:.|.:.||..:....  |..|::..::...     |...:::..:|   |:....
  Fly   424 ADDIVYIT-LQDLQNQTDKNIAPKTLPIWVRYMELILKGTRHAGNIQMTQNLTIITSQADITYLQ 487

  Fly   337 NLASNL-----LYKERFLDPATLQQYTQEVTKVFEQLRRQFLLQINENRLGLTSE---------- 386
            |:...|     .:.|.:|..:|:::.....:.....|..:::      |:.:.:|
  Fly   488 NIVEYLDDTPASHIESYLFLSTIEELVLHTSSSMRLLHSEYM------RVAIGTEGSTPRSLYCA 546

  Fly   387 --QNSMVATKAQHVVLNIG----NLPRGRDHRSFVSRHYEDLVFPLPDFDYARE----------- 434
              .||::.....:|:.:..    .||:.....|.:.|.::.||......|.|.:
  Fly   547 NGVNSLLGMAVSYVLADADFTKEKLPKVERMLSDIRRSFDRLVKSTSWMDAATKRKTIQKSAEMK 611

  Fly   435 ----------------------------HL-NLLEFRTRKQVLQLNQSAPTPDEFFYLSDPKTAM 470
                                        || ||::|...:.:.:||: ...|:...:.:.|...
  Fly   612 SFIGFPPWLRNASVLNAYYEGAEVNASTHLENLMDFVHWQMMDKLNE-MDKPEPIGWATSPSNV- 674

  Fly   471 SSGPYYLMRLNIIVVPHGLLQEPFFAADSHDIFKYSLLGFVLAHELMHSVDTVGLYYDRYGNIHE 535
              ..::..:.|.|.||..:||.||:.. ..:...|..:|.:|.|||.|..|..|..:||.||:.|
  Fly   675 --NAFHTFQSNAITVPIAILQYPFYDL-GLEALNYGSIGTILGHELTHGFDDSGRRFDRAGNMVE 736

  Fly   536 IGPQISSSPRFVAGLQCLNRNSTQY--------------LDERIADIAGLD---LAYSTYFQ--N 581
            .... .:...:|...:|.....::|              |.|.|||..|:.   .||..|.:  .
  Fly   737 WWSN-RTIDEYVNRTECFVEQYSRYHLADIDEYIDGELTLGENIADNGGMREAFYAYRLYVKEVG 800

  Fly   582 SSQMSLTDFTTIPPQQIFFLNLAQFFCGDGDPI--NFV---GHDNDETRLQQMLNGFAPFHEAFG 641
            ..:..|........:|:||::....:|....|.  .:.   .|...:.||:.:|:....|...|.
  Fly   801 RERSKLPGLEHYSHEQLFFISFGNLWCETYTPAASRYALTDSHCPGQMRLRGVLSNSEEFARTFK 865

  Fly   642 C----PAKSNQPEKCQLW 655
            |    |...:|| ||::|
  Fly   866 CARGTPMNPDQP-KCRIW 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	47..653	CDD:341056	140/775 (18%)
Nep5	NP_733186.2	M13	151..880	CDD:341056	141/780 (18%)