Protein Alignment Nepl6 and Nepl15

DIOPT Version :10

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Alignment Length: 749
• Identity: 162/749 - (21%)
• Similarity: 273/749 - (36%)
• Gaps: 172/749 - (22%)

  Fly     5 ACLFIVPICAA------PTTQNVEADPNSRLMN--NILSYVA-EDSSACGTYFQYACGKYAVRHR 60
            |.||  .|||.      |...|...| ..||..  :|.:|:. |...||..::.|||..:...|
  Fly    12 AILF--SICAIDASVPHPLAANYSID-ILRLAKAAHIKAYMGDEKEQACNNFYNYACANWPRLH- 72

  Fly    61 DDPFTEIIQMLDHKVNGNLVQLMHELHQRSQSPGFN------ESSVEAKVLHFYRTCREAPPSTR 119
              |..:      .|...|.::.:.||:.|..:....      |:|.:.::.:||.:||.....||
  Fly    73 --PARK------SKTRTNYLEELQELYIRKSADMLKSATRGAENSADRQLKYFYGSCRLQTNDTR 129

  Fly   120 KMEHYLRLAPPGQALT-----WPQFMPRGEPWPKAQFKWMKSLGHLYRYGFTNVLVNVLVLRSSE 179
            ...:.|      |.:|     ||:.  |...|.:.::.|::.:.:|.|....::.:.:.|:...:
  Fly   130 SALNTL------QNVTDFRGGWPEI--RVASWYQYEYDWLQVVANLKRKLGVDIFIGLEVILDYK 186

  Fly   180 NSNRFRLDISMPSLEGDAQHLGGFLSTLATLQIIGVPTKSILPLVRKIRRL-ESAIRVLTEVDDD 243
            .....||.|..|......:|.                   :.|.....|.: |.:|....::...
  Fly   187 EEKMHRLKIGAPQFPMSRRHY-------------------LHPHFEGTREIYERSIENKLKLYFP 232

  Fly   244 DESETW-----------------------------TLRQ---WEYKTGYAWQGFVESIVGHSVSH 276
            ::||.|                             |.||   .|.||.|.....|...:....:.
  Fly   233 EQSEHWRQEVASQVVQIEQQLAKGLPHNPALTLAQTTRQRTAAEMKTAYGSYVDVTRYLQLIFND 297

  Fly   277 HYVMQAQNA--KYFTGLKRLMDSTDAEVVANYIMTRFVLYLIDDFIDSNEHID--CVTDMRRNMN 337
            :..|.....  .|.:.|..::..|....:|||.|.:.:..|....:.:::..|  ||...::...
  Fly   298 NLYMDLYETPEDYMSNLVDVIRETPKLQLANYTMWKALEALDIARVPASQRADIWCVQLAQQFFP 362

  Fly   338 LASNLLYKERFLDPATLQQYTQEVTKVFEQLRRQFL--LQINENRLGLTSEQNSMVATKAQHVVL 400
            .....|:...:    ...|...|:...:..::|.|.  ||.:|..|.||.|......||.:.:.|
  Fly   363 HQLESLFHRNY----NHMQMINELQSTWSDIKRVFREDLQASERLLWLTLETRQKAITKLEALKL 423

  Fly   401 NIGNLPRGRDHRSFV----------SRHYEDLVFPLPDFDYAREHLNLLEFRTRKQVLQLNQSAP 455
            :.    |..|....:          .|.|.:||             ::|:::|::.:.:|.....
  Fly   424 HF----RTHDDNKLIRQMHGLILNMDRFYPNLV-------------SVLQWKTQRGLAKLMTEPV 471

  Fly   456 TPDEFFYLSDPKTAMSSGPYYLMRLNIIVVPHGLLQEPFFAADSH-DIFKYSLLGFVLAHELMHS 519
            ..||...|          |:|.::.|.|.||...||..||...:: :..||:.||.:||.:::|.
  Fly   472 AEDEVHKL----------PHYEIQKNRIQVPITFLQARFFWDPAYPNGLKYATLGVLLARQMLHG 526

  Fly   520 VDTVGLYYDRYGNIHEIGPQISSSPRFVAGLQCLNRNSTQYLDER-------------IADIAGL 571
            .|.||..||.||..:......|.| .:....||.......:::.:             :||...|
  Fly   527 FDGVGRRYDAYGYKNNWWDHTSES-SYSRRTQCFQEQYAIFVEYKGKPVQDKDLLRRIVADNGAL 590

  Fly   572 DLAYSTYFQ---NSSQ---------MSLTDFTTIPPQQIFFLNLAQFFCGD-GDPINFVGHDNDE 623
            |:||..|.|   |:::         :.|.|.   ...|||:|..||.:|.| .:.:.......::
  Fly   591 DIAYRAYQQWLKNAAETPVIYQRERLPLLDH---DHNQIFYLGYAQLYCTDYPETVERFDELPEQ 652

  Fly   624 TRLQQMLNGFAPFHEAFGC--PAKSNQPEKCQLW 655
            .|:...|:....|..|:||  ..|.|...||.|:
  Fly   653 LRVNTALSNSQQFANAYGCSREEKLNARFKCTLY 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	47..653	CDD:341056	144/694 (21%)
Nepl15	NP_651098.2	M13	56..684	CDD:341056	146/698 (21%)