Protein Alignment Nepl6 and Nepl13

DIOPT Version :10

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 821
• Identity: 170/821 - (20%)
• Similarity: 307/821 - (37%)
• Gaps: 254/821 - (30%)

  Fly     2 WL-----IACLFIVPICAAPTTQNVEAD--------PNSR--------LMNNILSYVAEDSSACG 45
            ||     :..||.:.:|.....:....:        |:||        :..::..|:...:..|.
  Fly     8 WLGFLLELLLLFEIQLCDVTEARQNHMNRMQMSGNFPDSREEQLVRQKIATDVQKYMNLSADPCT 72

  Fly    46 TYFQYACGKYAVRH----RDDPFTEIIQMLDHKVNGNLVQLMHE-LHQRSQSPGFNESSVE--AK 103
            .:|:||||::...|    |.|..:...|:::.|::..|.||:.: |..:....|::.:|:.  .|
  Fly    73 DFFEYACGQWGRYHKRQLRPDELSTAQQLMETKISEQLQQLLTQPLPPQHHPNGYSGASMTNVRK 137

  Fly   104 VLHFYRTC--REAPPSTRKMEHYLRLAPPGQALTWPQFMPRGEP---WPKAQFKWMKSLGHLYR- 162
            |..||.:|  .||..|.|: ...:::......|       |..|   |...: :|:::||.|.|
  Fly   138 VRAFYESCVAVEANASERR-RFLMKILKDNGGL-------RNVPNSNWQHNR-QWVQTLGELRRN 193

  Fly   163 YGFTNVLVNVLVLRSSENSNRFRLDISMPSLEGDAQHLGGFLSTLATLQIIGVPTKSILPLVRKI 227
            ||. ::|:.:            .:|:::.:::|:..:.|....|:       :|.:....|..:.
  Fly   194 YGL-DILLGL------------EIDLNLQTMKGNTIYFGEPKLTI-------IPAEHCNALATRG 238

  Fly   228 RRLESAIRVLTEVDDDDESETWTLRQW-EYKTGYAWQGFVESIVGHSVSHHY------------- 278
            .::...:..|.:     :..|..||.| ...||.|     ....|..:...:
  Fly   239 AQVRDEVYELVQ-----QQVTENLRDWFGMDTGEA-----ARFAGDIIRFEFELCKQMGEQDIQK 293

  Fly   279 -------VMQAQ--NAKYFTGLKRL------MDSTD-AEVVANYIMTRFVLYLIDD-------FI 320
                   .:|||  .|:..||.:||      |..|: ...:.|::..:.::.:|.:       ::
  Fly   294 PEEEFPPAIQAQIYGARSRTGQERLRRQKGGMTLTELTSEMGNHLDFKMLVEVILESQYPSQVYL 358

  Fly   321 DSNEHI-DCVTDMRRN--MNLASNLLY----------------KERFLDPATLQQYTQEVTKVFE 366
            .|.|:: ..|..::.|  :.:...:||                :.|.....|.:.:.|.:.::|:
  Fly   359 RSPEYVKHVVRTVKANNRITVGGYILYVALNELNQPPEEAPSQRARQCVQVTQRLFPQVLGEMFQ 423

  Fly   367 Q---------------------LRRQFLLQ-INENRLGLTSEQNSMVATKAQHVVLNIGNLPRGR 409
            :                     |..||.:: ::||      ::.:.....:|:.|    :||
  Fly   424 RHVQRDNAKHDLDAVFNDVIKALEEQFHVEWMDEN------DRRAARTRLSQYRV----SLP--- 475

  Fly   410 DHRSFVSRHYEDLVFPLPDFDYAREHLNLLEFRTRKQVLQL-----NQSAPTPDEFFYLSDPKTA 469
            |::|.   ...||.|...: ||.|.....|::|:.:|...|     .|.|...|.|    :.:.|
  Fly   476 DYQSL---DLTDLQFQKSE-DYWRRLEIALKYRSHQQFEALRGNDFGQDADGLDAF----EVRAA 532

  Fly   470 MSSGPYYLMRLNIIVVPHGLLQEPFFAADSHDIFKYSLLGFVLAHELMHSVDTVGLYYDRYGNIH 534
            :|.      |..:::|..||||.|::........||:|||..||..|:.:.|      |...|.|
  Fly   533 LSP------RQQMVLVGWGLLQAPYYNYYYPKSLKYALLGHRLASALVQAFD------DEGWNNH 585

  Fly   535 EIGPQISSSPRFVA------GLQCLN--------------RNSTQYLDERIADIAGLDLAYSTYF 579
               ||.::....|.      ..:|..              ||:|: |.|.|||.:||:||::.|.
  Fly   586 ---PQATAQWNEVTMSGYRNASECQRAQYSSYLYNEPGEFRNATR-LREIIADGSGLNLAFNAYL 646

  Fly   580 QNSSQ-------------MSLTDFTTIPPQQIFFLNLAQFFCGDGDPINFVGHDNDETRLQQM-- 629
            ....|             :|..:||.   .|:||:..||..|.        ..||.:..|..|
  Fly   647 AWLEQQDHKLRPLLAKETLSELNFTN---TQLFFIYFAQTRCW--------AKDNQDAILDSMPL 700

  Fly   630 -------------LNGFAPFHEAFGCP--AKSNQPEKCQLW 655
                         |:..|.|...|||.  ...|..:||.::
  Fly   701 MQHTPERWDVNGPLSNSAEFGREFGCALGTPMNSGDKCLVY 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	47..653	CDD:341056	159/751 (21%)
Nepl13	NP_651096.1	M13	68..738	CDD:341056	159/756 (21%)