Protein Alignment Nepl6 and Nepl12

DIOPT Version :10

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_649924.1
• Gene: Nepl12 / 41172
• FlyBaseID: FBgn0037727
• Length: 702
• Species: Drosophila melanogaster
• Alignment Length: 766
• Identity: 162/766 - (21%)
• Similarity: 276/766 - (36%)
• Gaps: 188/766 - (24%)

  Fly     1 MWLIACLFIVPICAAPT--TQNVEADPNSRLMNN-------------ILSYVAEDSSACGTYFQY 50
            :|:|... ::..|.|.:  .::..:|.|....|.             :.||:.:....|..:::|
  Fly    14 LWVIVAA-VLTDCEARSLVDRSENSDSNGSSTNRSAAEYQLQEYAEFMKSYMNQSVEPCENFYEY 77

  Fly    51 ACGKYAVRHRDDPFTEIIQMLDHKVNGNLVQLMHELHQRSQ-SPGFNESSVEAKVLHFYRTCREA 114
            |||.|. ..:.|.::...:.....|...|:.:..:|..|.. :...|.||..|....||..|..|
  Fly    78 ACGNYR-NVKPDRYSPGSRSNLGDVTYTLIDITEQLLGRMDLAEALNVSSELAVAQRFYNACLGA 141

  Fly   115 --PPSTRKMEHYLRLA------PPGQALTWPQFMPRGEPWPKAQFKWMKSLGHLYRYGFTNVLVN 171
              .|.......||.|.      |...          |:.|..:.|.|:....||..||...::..
  Fly   142 NLHPFNAADPAYLSLIRSIGGFPAVD----------GDAWKASNFNWINMSAHLANYGANGLIRE 196

  Fly   172 VLVLR-----------------------SSENSNR-FRLDISMPSLEGDAQHLGGFLSTLATLQI 212
            .|.||                       .|.|:.| |||         :.:.:.|:      |:.
  Fly   197 TLQLRYPFEPYTKLPELGFDHIIVHEENISRNTTRAFRL---------NEERMHGY------LRA 246

  Fly   213 IGVPTKSILPLVRKIRRLESAI-------RVLTEVDDDDE-SETWTLR----QWEYKTGYAWQGF 265
            .|:|..          |:..||       |...|:....| .:.:.::    |.||....:|.|.
  Fly   247 FGLPED----------RIREAIAGVFAFWRDALEIPPQCEVFDPYRIKRVFPQSEYYYNISWSGL 301

  Fly   266 VESIVGHSVSHHYVMQAQNAKYFTGLKRLMDSTDAEVVANYIMTRFVLYLIDDFIDSNEHID--C 328
                  ||.:..:.     ..|:..|.::. :...:.||||:..: :||..|..:.:..:..  |
  Fly   302 ------HSTNKLFC-----DFYYVELDKVC-ARHRKAVANYLAMK-LLYRFDPKLKAPRYQRNYC 353

  Fly   329 VTDMRRNMNLASNLLYKERFLDPATLQQYTQEVTKVFEQLRRQFLLQINENRLGLTSEQNSMVAT 393
            ...:.::|....|.||.......|...:.::.|.::.:.||:..     |:...|.:|..:....
  Fly   354 SVTLYQSMRFLFNKLYMANNFSEAKRLEMSEMVRELRKSLRKAL-----EDADWLDAESRARALL 413

  Fly   394 KAQHVVLNIGNLPRGRDHRSFVSRHYEDLV------FPLPDFDYAREHLNLLEFRTRKQVLQLNQ 452
            |...:...||         ||......|.:      ..:.:..||..::||     :..|:|:|:
  Fly   414 KESRIQPRIG---------SFQDDALSDRIIREINSLKVIEDRYAETNINL-----QHLVVQINR 464

  Fly   453 -SAPTPDEFFYLSDPK---TAMSSGPYYLMRLNIIVVPHGLLQEPFFAADSHDIFKYSLLGFVLA 513
             |:....|....:.|:   |.:..|..|....|.|.|..|:::.|.:........|:..|||::.
  Fly   465 FSSRHFQELTNDTKPQKILTGLQVGAGYYTPDNSINVMAGVVEPPIYQRHLPISLKFGTLGFIVG 529

  Fly   514 HELMHSVDTVGLYYDRYGNIHEIGPQISSSPRFVAGLQCLNRNSTQY------------------ 560
            |||:|..||...|:|..|::..:..:||.        |.|...:..|
  Fly   530 HELIHGFDTTSSYFDGNGHMESLLSEISQ--------QALEDRAECYMDYYGKYQVPEISRRVNG 586

  Fly   561 ---LDERIADIAGLDLAYSTY-------FQNSSQMSLTDF---TTIPPQQIFFLNLAQFFCGDGD 612
               |||.|||.:||..|.:.|       .::..|..::|.   ..:.|:|:|||..||.||...:
  Fly   587 KTTLDENIADNSGLRQALTAYRSHRQQLLEHPGQERISDAMPGLDLTPEQLFFLGFAQLFCSHYE 651

  Fly   613 PINFVG-----HDNDETRLQQMLNGFAPFHEAFGCPAKSNQ---PEKCQLW 655
            ..::..     |..|:.|:..:|:....|..|:.|...|..   .:.|:||
  Fly   652 EEHYWKGLSDVHTFDQFRVLGVLSNSEDFFHAYNCSVGSGMRPGAKTCRLW 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	47..653	CDD:341056	149/701 (21%)
Nepl12	NP_649924.1	M13	68..700	CDD:341056	150/707 (21%)