Protein Alignment Nepl6 and Ece2

DIOPT Version :10

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_038944493.2
• Gene: Ece2 / 408243
• RGDID: 1303039
• Length: 789
• Species: Rattus norvegicus
• Alignment Length: 666
• Identity: 152/666 - (22%)
• Similarity: 257/666 - (38%)
• Gaps: 147/666 - (22%)

  Fly    28 RLMNNILSYVAEDSSACGTYFQYACGKY-------AVRHRDDPFTEIIQMLDHKVNGNLVQLMHE 85
            |:...||..:....|.|..::|::||.:       :.|.|.:.|..:...       |...|.|.
  Rat   179 RVAGKILESLDRGVSPCQDFYQFSCGGWIRRNPLPSGRSRWNTFNSLWDQ-------NQAILKHL 236

  Fly    86 LHQRSQSPGFNESS-VEAKVLHFYRTCREAPPSTRKMEHYLRL-APPGQALT-----WPQFMPRG 143
            |    ::..||.|| .|.|...||.:|..       :|...:| |.|.|.|.     |    ...
  Rat   237 L----ENSTFNSSSEAERKTRSFYLSCLH-------LERIEKLGAKPLQDLIDKIGGW----NIT 286

  Fly   144 EPWPKAQF-KWMKSLGHLYRYG--FTNVLVNVLVLRSSENSNRFRLDIS---MPSLE------GD 196
            .||.:..| :.:|::...||..  ||   |.|.....|.|||..::|.|   :||.:      .:
  Rat   287 GPWDEDNFMEVLKAVAGTYRAAPFFT---VYVGADSKSSNSNIIQVDQSGLFLPSRDYYLNRTAN 348

  Fly   197 AQHLGGFLSTLATLQII--GVPTKSILPLVRKIRRLESAIRVLTEVDD---DDE--------SET 248
            .:.|..:|..:..|.::  |.|| |....::::..||..:..:|...|   |:|        ||.
  Rat   349 EKVLAAYLDYMVELGMLLGGQPT-STRAQMQQVLELEIQLATITVPQDQRRDEEKIYHKMSISEL 412

  Fly   249 WTLRQWEYKTGYAWQGFVESIVGH-SVSHHYVMQAQNAKYFTGLKRLMDSTDAEVVANYIMTRFV 312
            .||     .....|..|:..::.. .:.....:.....:|...:..|::.|:..::.||::...|
  Rat   413 QTL-----APSMDWLEFLSFLLSPLELGDSEPVVVYGTEYLQQVSELINRTEPSILNNYLIWNLV 472

  Fly   313 ----LYLIDDFIDSNEHI----------------DCVTDMRRNMNLASNLLYKERFLDPATLQQY 357
                ..|...|..:.|.:                .|:::....:..|...|:.:     ||..:.
  Rat   473 QKTTSSLDQRFETAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVK-----ATFDRQ 532

  Fly   358 TQEVTK-VFEQLRRQFLLQINENRLGLTSEQNSMVATKAQHVVLNIGNLPRGRDHRSFV--SRHY 419
            ::|:.: :..::|..| .:..||.:.: .|:..:.|.:....:.::...|      .|:  .|..
  Rat   533 SKEIAEGMISEIRAAF-EETLENLVWM-DEKTRLAAKEKADAIYDMIGFP------DFILEPREL 589

  Fly   420 EDLV--FPLPDFDYAREHLNLLEFRTRKQVLQLNQSAPTPDEFFYLSDPKTAMSSGPYYLMRLNI 482
            :|:.  :.:.:..:.:..|||..|..:....|| :..|:.|::     ..|..:...|||...|.
  Rat   590 DDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQL-RKPPSRDQW-----SMTPQTVNAYYLPTKNE 648

  Fly   483 IVVPHGLLQEPFFAADSHDIFKYSLLGFVLAHELMHSVDTVGLYYDRYGNIHEIGP--QISSSPR 545
            ||.|.|:||.||:|.:......:..:|.|:.|||.|:.|..|..||:.||:.   |  |..|...
  Rat   649 IVFPAGILQAPFYAHNHPKALNFGGIGVVMGHELTHAFDDQGREYDQEGNLR---PWWQNESLTA 710

  Fly   546 FVAGLQCLNRNSTQY------------LDERIADIAGLDLAYSTY---------FQNSSQMSLTD 589
            |.....|:.....||            |.|.|||..||..||:.|         .|....:.||:
  Rat   711 FQNHTACMEEQYNQYQVNGERLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEEQPLPAVGLTN 775

  Fly   590 FTTIPPQQIFFLNLAQ 605
                  .|:||:..||
  Rat   776 ------HQLFFVGFAQ 785

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	47..653	CDD:341056	147/647 (23%)
Ece2	XP_038944493.2	None