Protein Alignment Nepl6 and Nepl11

DIOPT Version :9

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Alignment Length: 697
• Identity: 133/697 - (19%)
• Similarity: 220/697 - (31%)
• Gaps: 238/697 - (34%)

  Fly    31 NNILSYVAEDSSACGTYFQYACGKYA-----VRHRDDPFTEIIQMLDHKVNGNLVQLMHELHQRS 90
            :|:..|:......|..::.|.|...|     .|.|   |..:::..|      :.|||
  Fly    33 HNLEPYLDTSKQPCQDFYGYVCSHSANLSETGRQR---FQSLLKETD------VAQLM------- 81

  Fly    91 QSPGFNESSVEAKVLHFYRTCREAPPSTRKMEHYLRLAPPGQALTWPQFMPRGEPWPKAQ----- 150
                    .:|.::::|:::|.    |.|.:|          ||...|...:...||..:
  Fly    82 --------DMELQLINFFKSCE----SGRGVE----------ALKGSQLYRQSGGWPSLEPNKVN 124

  Fly   151 --------FKWMKSLGHLYRYGFTNVLVNVLVLRSSENSNRFRLDISMP------SLEGDAQHLG 201
                    .:|:..||:.:..|........:.::|::     ||.:..|      :|....|.:|
  Fly   125 ASQRTNQTQRWLGLLGYFHEVGAPYFFETSVTMQSNK-----RLVVLQPDGTRRNTLRKFEQRVG 184

  Fly   202 GFLSTLATLQIIGVPTKSILPLVRKIRRLESAIRVLTEVDDDDESETWTLRQWEYKT------GY 260
                  ..||..|:..........::..||.:.|.:.:.|..::..     |:.|..      |.
  Fly   185 ------EVLQSFGIEQSRAHVTALEVLSLERSRRDIVKADHVEDQV-----QFSYGNFKRIVFGN 238

  Fly   261 A------WQGFVESIVGHSVSHHYVMQAQNAKYFTGLKRLMD------STDAEVVANYIMTRFVL 313
            |      |.|:...::|....     ||.:......|.||::      :|....:.|:|.|.:::
  Fly   239 ASLIRLDWDGYFRKLLGGKTP-----QASDTIVVKQLPRLVEYFALLQNTSMVRLLNWIWTDYLM 298

  Fly   314 YLIDDFIDSNEH--------------IDCVTDMRRNMNLASNLLYKERFLDPATLQQYTQE---- 360
                |.:|::.|              :..||..|  :.||.  :|.|  |..|    ||.:
  Fly   299 ----DIVDADCHQLSETYAGDLYAHVVQRVTANR--VELAQ--MYSE--LGKA----YTDQLGGS 349

  Fly   361 --VTKVFEQLRRQFLLQINENRLGLTSEQNSMVATKAQHVVLNIGNLPRGRDHRSFVSRH--YED 421
              :.::..|..||||..|                   .|..||.........|...:.|.  |.:
  Fly   350 VWIDEISRQSSRQFLGNI-------------------MHTTLNGDERLDAAYHSILLGRRSLYRN 395

  Fly   422 LVFPLPDFDYAREHLNLLEFRTRKQVLQLNQSAPTPDEFFYLSDPKTAMSSGPYYLMRLNIIVVP 486
            |           |.|...: |||:..   :.||.....:..:..|             :|..:..
  Fly   396 L-----------EKLRKFQ-RTRRLA---SHSAQQVRRYAQMFAP-------------VNAFLGQ 432

  Fly   487 HGLLQEPFFAADSHDIFKYSLLGFVLAHELM---HSVDTVGLYYDRYGNIHEIGPQISSSPRFVA 548
            |. |..|         ..|.|||...:..|:   .|..|.|.:...           .|..||..
  Fly   433 HN-LSTP---------LNYLLLGEFFSRSLVAAGSSSRTQGAWRSS-----------DSERRFAI 476

  Fly   549 GLQCLNRNSTQYLDERIADIAGLDLAYSTYFQ------------------NSSQMSLTDFTTIPP 595
            ..||:.: .|..:|..::.:|... |.|.|.|                  .||:|||
  Fly   477 FQQCVGK-QTNAIDLLLSLLAQRQ-ALSAYGQWLATQAGLVERVDAVLAAGSSKMSL-------- 531

  Fly   596 QQIFFLNLAQFFCGDGDPINFVGHDNDETRLQQMLNGFAPFHEAFGC 642
            |::||:......|  ...:..:..|.........|.....|.|||.|
  Fly   532 QRLFFVTSLLVDC--RSELGALQQDRKRQVTHATLRNSPEFLEAFRC 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	42..653	CDD:189000	131/686 (19%)
Nepl11	NP_649449.1	GluZincin	45..589	CDD:301352	131/685 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910