Protein Alignment Nepl6 and Nepl5

DIOPT Version :9

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Alignment Length: 715
• Identity: 200/715 - (27%)
• Similarity: 333/715 - (46%)
• Gaps: 100/715 - (13%)

  Fly     2 WLIACLFIVPICAAPTT---QNVEADPNSRLMNNILSYVAEDSSACGTYFQYACGKYAVRHRDD- 62
            |||   |.:.....||.   .|........|...:.||:...:..|..::|||||.:.::.::.
  Fly     9 WLI---FSLAWRTTPTACRQTNAPQSVQEMLAEQLQSYMDTKARPCENFYQYACGNWQIQQQEQH 70

  Fly    63 -------------------PFTEIIQMLDHKVNGNLVQLMHELHQRSQSPGFNESSVEAKVLHFY 108
                               | |:.:.::||.||..|..|   |.:|::|...::||:..::..:|
  Fly    71 SLRDRDWTRDRQRYQGQMLP-TDTLGLIDHSVNRKLELL---LRRRNESSFESDSSILEQMRLYY 131

  Fly   109 RTCREAPPSTRKMEHYLRLAPPGQALTWPQFMPRGEPWPKAQFKWMKSLGHLYRYGFTNVLVNVL 173
            |:|:...|  ..::.||:|.||..:..||..   |..|...:|.|:.:||.|..:|...||:...
  Fly   132 RSCKRLKP--YNLKKYLQLLPPSNSTQWPSV---GRGWRPERFDWITTLGRLRLHGLNGVLLREE 191

  Fly   174 VLRSSENSNRFRLDISMPSLEGDAQHLG-GFLSTLATLQIIGVPTKSILPLVRKIRRLESAIRVL 237
            ||...::|..:.:.::.||.: :.|.:| |.:..|  |..||...::...|.|::...|..:..|
  Fly   192 VLPRWDDSRNYSIYVNKPSRQ-ETQPMGEGAMIEL--LLDIGQTKRTANALARQVDDFERKLHRL 253

  Fly   238 TEVDDDDESETWTLRQWEYKTGY--------AWQGFVESI-VGHSVSHHYVMQAQNAKYFTGLKR 293
            .|::||:...       |.:.||        .|..|:..: :...:.....:..:|..|...|..
  Fly   254 QELEDDEGPR-------EMQLGYLDSYLPQLRWLSFMRQVRIDSELDLRSTLIIENIPYLRALSD 311

  Fly   294 LMDSTDAEVVANYIMTRFVLYLIDDFIDSNEHIDCVTDMRRNMNLASNLLYKERFLDPATLQQYT 358
            ||:|...:.|.:|||.:::.:|...........:||..:||.|.|||:.|..::|.||.: :.|
  Fly   312 LMESESPDTVCSYIMLKWLAFLKQQGPADISRGECVAALRRAMPLASSWLVGQQFSDPES-ESY- 374

  Fly   359 QEVTKVFEQLRRQFLLQINENRLGLTSEQNSMVATKAQHVVLNIGNLPRGRDHRSFVSRHYEDLV 423
              |:.:|::|:.:|...:.|||:.|:.....::..|.:.|.|.:|         .|.:...||:.
  Fly   375 --VSSLFQRLKVRFGQILAENRMRLSPPLVHILQQKLRAVRLQMG---------FFQTEEIEDVE 428

  Fly   424 -----FPLPDFDYAREHLNLLEFR--TRKQVLQLNQ---SAPTPDEFFYLSDPKTAMSSGPYYLM 478
                 ..|....:....|.||..|  ....:|.:|.   :..|.....|||:...|.:|.|.|:.
  Fly   429 QYHVRIDLSGHSFYGNQLVLLRQRVEANHDLLYINVTNFANSTGSNLSYLSESWEASNSSPLYVR 493

  Fly   479 RLNIIVVPHGLLQEPFFAADSHDIFKYSLLGFVLAHELMHSVDTVGLYYDRYGNIHEIGP--QIS 541
            ..|:::|||||||.|.:..:...:.:::::||||||||.|..|.:|:.||..|||  :||  :|.
  Fly   494 PRNLVLVPHGLLQLPIWHRNISALQQHAVMGFVLAHELAHGFDMLGMDYDAMGNI--MGPVEEIG 556

  Fly   542 SSPRFVAGLQCLNR---NSTQYLDERIADIAGLDLAYSTYFQNSSQMSLTDFTTIPPQ----QIF 599
            :|.:|..|||||.:   ..::::||::||...|.|||.|:|....:....|  .:.||    |:|
  Fly   557 ASRQFRQGLQCLQQQMATGSKWIDEKLADFVALRLAYETFFGVRDKREPRD--PLLPQFSQRQLF 619

  Fly   600 FLNLAQFFCGDGDPIN-------FVGHDNDETRLQQMLNGFAPFHEAFGC--PAKSNQPEKCQLW 655
            |:..||||||....::       .:.|..||.|:.|.|..|..|...|||  .||....::|::|
  Fly   620 FITFAQFFCGRTPVLSPRSQSEAHLKHAADELRVMQTLANFEEFSREFGCDKKAKMQASQRCRIW 684

  Fly   656  655
              Fly   685  684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	42..653	CDD:189000	188/668 (28%)
Nepl5	NP_609022.1	PepO	42..684	CDD:226118	191/677 (28%)
		GluZincin	48..682	CDD:301352	188/669 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469640
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006719
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840