Protein Alignment Nepl6 and Nepl4

DIOPT Version :9

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_609019.1
• Gene: Nepl4 / 33889
• FlyBaseID: FBgn0031805
• Length: 652
• Species: Drosophila melanogaster
• Alignment Length: 700
• Identity: 176/700 - (25%)
• Similarity: 286/700 - (40%)
• Gaps: 114/700 - (16%)

  Fly     6 CLFIVPICA------APTTQNVEADPNSRLMNNILSYVAEDSSACGTYFQYACGKYAVRHRDDPF 64
            |...||:.|      .|......:..|.:.::.::|||..:.:.|..::.|||||:..:|  ...
  Fly    17 CGSSVPVKANDPEQSCPYLGECNSTINQQHIDTLMSYVDSEKNPCEDFYAYACGKWRAKH--GSH 79

  Fly    65 TEIIQMLDHKVNGNLVQLMHELHQRSQSPGFNESSVEAKVLHFYRTC--REAPPSTRKMEHYLR- 126
            |....:.:.::|.....|..:|.:...:|.:. ..:.||||..|::|  .|.|...|.:|...|
  Fly    80 TTATMISESQINRQYEDLFLQLLRNPSAPEYG-YPMFAKVLAHYQSCIALEKPDLRRYIELLDRD 143

  Fly   127 -LAPPGQALTWPQFMPRGEPWPKAQFKWMKSLGHLYRYGFTNVLVNVLVLRSSEN--------SN 182
             ||.....                  .||..|..|.|||:....|.|.|...:..        .|
  Fly   144 LLASLNST------------------HWMHLLAALGRYGYHGHYVQVEVRWYNATHHMIFLLPHN 190

  Fly   183 RFRLDISMPSLEGDAQHLGGFLSTLATLQIIGVPTKSILPLVRKIRRLE-SAIRVLTEVDDDDES 246
            | .|::|:.....||            |...|.....:..|..:.|.|| :.:|:......||..
  Fly   191 R-HLNLSLTQDIYDA------------LSQDGSSWPPLHQLQEQFRSLEQNLVRLAKPHSADDTF 242

  Fly   247 ETWTLRQWEYKT-GYAWQGFVESIVGHSVSHHYVMQAQNAKYFTGLKRLMDSTDAEVVANYIMTR 310
            ..::|.|...:. |..|...:.:.:|.||..::|.|..:.....||...:::.|..::..|.:.|
  Fly   243 RNYSLDQIRTEVPGLHWDEALRTQLGRSVPGNHVFQVDDLDAIEGLVEYLNTVDTLLLNRYSLAR 307

  Fly   311 FVLYLID---------DFIDSNEHIDCVTDMRRNMNLASNLLYKERFLDPATLQQYTQE--VTKV 364
            |:.:|::         :....:...:|:..|||::.|..|.:|:..|.   :.:::..|  :..|
  Fly   308 FLSHLLELPHNPLATWESGQRSRGRNCIRHMRRSVYLPMNYVYERSFY---SRRRHADELVIHSV 369

  Fly   365 FEQLRRQFLLQINENRLGLTSEQNSMVATKAQHVVLNIGNLPRG--------RDHRSFVSRHYED 421
            |:||:.|..|::..|...|:.:....:..|...:.:|:||||..        .|.|..|.|
  Fly   370 FQQLQSQLELRVQHNAFNLSQDLVKSLQAKVHQMRINVGNLPPNVTEQFYWDSDRRWSVGR---- 430

  Fly   422 LVFPLPDFDYAREHLN-LLEFRTRKQVLQLNQSAPTPD-EFFYLSDPKTA-----MSSGPYYLMR 479
                    |:...||| ||.:.|  .|..|..|:...: :.:|..:..|.     :.:.||:...
  Fly   431 --------DFYENHLNSLLYYYT--LVADLESSSDQEERDIWYSFNMHTPEFPDNIDATPYFYCL 485

  Fly   480 LNIIVVPHGLLQEPFFAADSHDIFKYSLLGFVLAHELMHSVDTVGLYYDRYGNIHEIGPQISSSP 544
            .|||.||:..::.|||.|:......|..|...|.||:||:.||..:.||..||:.....|:....
  Fly   486 GNIIFVPYSYVKRPFFDANFWPALLYGDLANTLGHEIMHAFDTDLVDYDAQGNLRNFSDQLGEVE 550

  Fly   545 RFVAGLQCLNRNSTQYLDERIADIAGLDLAYSTYFQNSSQMSLTDFTTIPPQ-QIFFLNLAQFFC 608
            .:...:.||| :|...|:||.:|::|..||..||.        .|:.|.... :::||..|.|||
  Fly   551 LYNGAVGCLN-SSAVMLNERTSDVSGSRLAMQTYG--------GDWLTRSGNGRLYFLQFAHFFC 606

  Fly   609 GD-GDPINFVGHDNDETRLQQMLNGFAPFHEAFGCPAKS--NQPEKCQLW 655
            || ||..    ||:...||...|.....|.|.|.|...|  ...::|..|
  Fly   607 GDEGDQY----HDSGSQRLNYALGQVPQFAEVFRCHVGSGMTSADQCPFW 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	42..653	CDD:189000	165/654 (25%)
Nepl4	NP_609019.1	PepO	51..643	CDD:226118	168/655 (26%)
		GluZincin	59..649	CDD:301352	165/653 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006719
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.910