Protein Alignment Nepl6 and Nepl3

DIOPT Version :10

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 696
• Identity: 199/696 - (28%)
• Similarity: 312/696 - (44%)
• Gaps: 135/696 - (19%)

  Fly     2 WLIACLFIVPICAAPTTQNVEADPNSRLMNNILSYVAEDSSACGTYF---QYACGKYAVRHRDDP 63
            ||: .|....:|:        |:||..:|..:|..:.|....|..::   |.....:|.....|.
  Fly    12 WLL-LLLCSTVCS--------ANPNLEIMKRMLDDMDEKVEPCHNFYNSSQKNLKWHAFATVSDQ 67

  Fly    64 FTEIIQMLDHKVNGNLVQLMHELHQRSQSPGFNESSVEAKVLHFYRTC--REAPPSTRKMEHYLR 126
            |..:...::::|                   |.:.|.|.|:...|:.|  .|.|...|    |..
  Fly    68 FQLLFDGIENEV-------------------FEKHSFEEKLQRLYKICSTMERPSLLR----YFE 109

  Fly   127 LAPPGQALTWPQFMPRGEPWPKAQFKWMKSLGHLYRYGFTNVLVNVLVLRSSENSNRFRLDISMP 191
            |..||:.|.||...|||..|||.:|:||::|..|.||||.:::.. :.:|...||     |...|
  Fly   110 LVKPGEDLNWPFLTPRGGKWPKEKFQWMEALARLRRYGFNDIMFG-MSIRQDPNS-----DSGQP 168

  Fly   192 SLEGDAQHLGGFLSTLATLQIIGVPTKSILPLVRKIRRLESAIRVLTEVD--------DDDESET 248
            .:..:.:: ......:.:||.||:|.|    |.::|..|::||:.:.:.|        |....:.
  Fly   169 IVVFEKKY-DSLFRFIESLQNIGLPPK----LAKEIAPLDNAIQEMYKSDMKFEHYARDAAPVKR 228

  Fly   249 WTLRQWEYKTGYAWQGFVESIVGHSVSHHYVMQAQNAKYFTGLKRLMDSTDAEVVANYIMTRFVL 313
            .:|.|.|. .|.:...::|.:.|...|..:|:..:|..|..||:.||.:..::|||||:..||..
  Fly   229 ISLGQLEI-YGVSLTKYLEIVFGRPFSPDFVVHVENLYYLRGLQNLMTAVPSQVVANYLTARFSF 292

  Fly   314 YLIDDFIDSNEHID-CVTDMRRNMNLASNLLYKERFLDPATLQQYTQEVTKVFEQLRRQFLLQIN 377
            |::..|:   :|.| |||.||::|..|||||::||.|....|:.|..:..|:|:.:|:|..:::.
  Fly   293 YIMFTFM---KHGDSCVTTMRQSMEFASNLLFEERILGRKKLRSYQNQAGKIFDAIRQQLNIRLE 354

  Fly   378 ENRLGLTSEQNSMVATKAQHVVLNIGNLPRGRDHRSFVSRHYEDLVFPLPDFDYAREHLNLLEFR 442
            .|.|.|...:.|::..|...:.|:|||||....||.||:|:|::|.| ..|.:.|..||.:||.|
  Fly   355 RNVLKLPPAEISLLQKKLNGLSLSIGNLPGKAGHRRFVTRYYKELEF-ADDEELATAHLKVLEHR 418

  Fly   443 TRKQVLQLNQ-----------SAPTPDEFFYLSDPKTAMSSGPYYLMRLNIIVVPHGLLQEPFFA 496
            ||.::..|:|           |.|..:.||     :||      |....|.|.|.:..|.:..|.
  Fly   419 TRAELSLLDQPNFKDRRYMLHSYPISNFFF-----ETA------YEENGNTIYVAYDFLADASFD 472

  Fly   497 ADSHDIFKYSLLGFVLAHELM----------HSVDTVGLYYDRYGNIHEIGPQISSSPRFVAGLQ 551
            .|||||||.:.||.....|::          |.|:.:.|:.|.         ||::     ||.:
  Fly   473 PDSHDIFKVTPLGIRFGLEMLKSFDLFNCKHHKVNMLQLFDDN---------QITT-----AGDE 523

  Fly   552 CLNR-NSTQYLDERIADIAGLDLAYSTYFQNSSQMS--LTDFTTIPPQQIFFLNLAQ-------F 606
            |::. .....|.:|...:..|.|.:..||...|:.|  ..:|||:..:::||....|       :
  Fly   524 CVSAWTQDNLLSQRDQYLVVLHLVHEAYFAEGSKFSQRQPNFTTMSLRELFFFRFGQSSFGQTLY 588

  Fly   607 FCGD----GDPINFVGHDNDETRLQQMLNGFAPFHEAFGCPAKSNQ 648
            |..|    |.|||.:      |||       ..|...|.|.|...|
  Fly   589 FGSDFVEGGSPINSL------TRL-------PVFVRTFNCLAPGEQ 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	47..653	CDD:341056	188/651 (29%)
Nepl3	NP_608904.1	GluZincin	42..>434	CDD:472708	130/430 (30%)