Protein Alignment Nepl6 and Nep1

DIOPT Version :9

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001284925.1
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Alignment Length: 711
• Identity: 163/711 - (22%)
• Similarity: 294/711 - (41%)
• Gaps: 124/711 - (17%)

  Fly    28 RLMNNILSYVAEDSSACGTYFQYACGKYAVRH---RDDPFTEIIQMLDHKVNGNLVQLMHE-LHQ 88
            |...::||.:..:|..|..:||||||.:...|   .|.......::|..:....|..::.| :.:
  Fly   180 RTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFEVLSDQQQVILRAVLEEPIDE 244

  Fly    89 RSQSPGFNESSVEAKVLHFYRTCREAPP----STRKMEHYLRLAPPGQAL-TWPQFMPRGEPW-P 147
            |.     |:::::||.  |:::|.:.|.    .|.:::..|      |:| .|| .:.|.  | |
  Fly   245 RD-----NKATIKAKT--FFKSCMDIPQIRKIGTGRLKQVL------QSLGGWP-VIERN--WSP 293

  Fly   148 KAQFKWMKSLGHLYRYGFTN-VLVNVLVLRSSENS--NRFRLD---ISMPSLE--------GDAQ 198
            .|.....:.:|.| |..::. |::.:.|....:||  |..::|   .::||.:        .|.:
  Fly   294 PADLSVERLMGQL-RLNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPSRDYYLKESSANDRR 357

  Fly   199 HLGGFLSTLATLQIIGVPTKSILPLVRKIRRLES-AIRV-LTEVDDDDESETWTLRQW------E 255
            ....:::.:|.|  :|....:....:.|:...|: .:.| |.|.|..|.|..:  |:.      |
  Fly   358 AYHRYMTQVALL--LGADPATAAAELEKVVLFETQLVNVSLPEADRHDTSLVY--RKMLLPELQE 418

  Fly   256 YKTGYAWQGFVESIVGHSV--SHHYVMQAQNAKYFTGLKRLMDSTDAEVVANYIMTRFVLYLIDD 318
            ......||.::::.:|..:  .....:......|.|.:.:::..||..||.||::.|.|:.|:..
  Fly   419 LVPEVQWQEYLQAALGPGIPLQEDEPLVTYGLHYLTEMGKILAHTDRRVVHNYMLWRLVMSLMSH 483

  Fly   319 FID--SNEHID-----------------CVTDMRRNMNLASNLLY-KERFLDPATLQQYTQEVT- 362
            .||  ..|.::                 ||....:.:.:|...|: ::.|      .|.::||.
  Fly   484 MIDEYQRERVEFRKILMGIQSERTRWSQCVEWTNKKLGVAVGALFIRDNF------NQESKEVAL 542

  Fly   363 KVFEQLRRQFLLQINENRLGLTSEQNSMVATKAQHVVLNIGNLPRGRDHRSFVSRHYEDLVFPLP 427
            ::...:|..|...:.||. .:..|..::...||..:...|| .|....:.:.:.:.|.:|.. :|
  Fly   543 EMIHTIRAAFNELLAEND-WMDDETRAVAKEKADSMNERIG-YPELLTNATELEQEYVNLTI-VP 604

  Fly   428 DFDYAREHLNLLEFRTRKQVLQLNQSAPTPDEFFYLSDPKTAMSSGPYYLMRLNIIVVPHGLLQE 492
            | ::....|::|::.:.|.:..|.|..   |:..:.::|...   ..:|....|.||.|.|:||.
  Fly   605 D-NFINNVLSILQWESEKMLRLLRQPV---DKEKWTTEPAVV---NAFYNPNKNDIVFPAGILQP 662

  Fly   493 PFFAADSHDIFKYSLLGFVLAHELMHSVDTVGLYYDRYGNIHEIGPQISSSPRFVAGLQCLNRNS 557
            .|::........|..:|.|:.||:.|..|..|..:|:.||:.:.... ::...|....||:....
  Fly   663 LFYSQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNN-ATIEAFRERTQCVIDQY 726

  Fly   558 TQY--------LD------ERIADIAGLDLAYSTYFQ------NSSQMSLTDFTTIPPQQIFFLN 602
            ::|        :|      |.|||..||..|:..|.:      ...|:...:.|   ..|:||||
  Fly   727 SRYKINEVDMFMDGRMTQGENIADNGGLKQAFRAYKKWETLHGREQQLPGLNMT---HDQLFFLN 788

  Fly   603 LAQFFCGDGDP------INFVGHDNDETRLQQMLNGFAPFHEAFGCPAKS--NQPEKCQLW 655
            .||.:||...|      |....|.....|:...|:....|..|:.||..|  |..|||.:|
  Fly   789 YAQIWCGSMRPEDALTKIRSAVHSPGFVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	42..653	CDD:189000	157/693 (23%)
Nep1	NP_001284925.1	M13	194..847	CDD:189000	157/693 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469687
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840