Protein Alignment Nepl6 and nep-18

DIOPT Version :9

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_494297.1
• Gene: nep-18 / 186911
• WormBaseID: WBGene00019343
• Length: 701
• Species: Caenorhabditis elegans
• Alignment Length: 783
• Identity: 148/783 - (18%)
• Similarity: 263/783 - (33%)
• Gaps: 238/783 - (30%)

  Fly     2 WLIACLFIVPICAAPTTQNVEADPNSRLMNNILSYVAEDSSACGTYFQYACGKYAVRHRDD---P 63
            |...|:.:  :......||...||                  |..:|::.||:|:....||   .
 Worm    28 WSKECVGV--LAMIKNYQNASVDP------------------CEDFFEHTCGRYSEHVMDDNSWG 72

  Fly    64 FTEIIQML-------------DHKVNGNL------------------VQLMHELHQRSQ----SP 93
            :.:..|:|             :.|.|..|                  ..|.:::.:|..    .|
 Worm    73 YVQYKQLLYQVFAIARKTNKFNSKPNEQLRIFTKSCLDRKEMDEDTFQDLRNDIEERGGFPMIDP 137

  Fly    94 GFNE-----SSVEAKVLHFYRTCREAPPSTRKMEHYLRLAP----PGQALTWPQFMPRGEPWPKA 149
            .:||     |.:.||.|..          .|....:|.:.|    .|.......::..|..|
 Worm   138 NWNEEKFDLSDMLAKYLSI----------NRNRMGFLSVEPYAAIEGNKSVNRLYVSPGPHW--- 189

  Fly   150 QFKWMKSLGHLYRYGFTNVLVNVLVLRSSE-NSNRFRLDIS-MPSLEGDAQHLGGFLSTLATLQI 212
            .:.|...:. :|:.....:|..:|.|.:.| |...:..:.: :..||.:       .||||..:.
 Worm   190 VYNWAMGIS-IYKDSVAFMLRRLLKLENRELNETIYDKEFAELVQLEAN-------FSTLADYRN 246

  Fly   213 IGVPTKSILPLVRKIRRLESAIRVLTEVDDDDESETWTLRQWEYKTGYAWQGFVESIVGHSVSH- 276
            :.:...:    :.|.|.|...::::.|:|                    |...::::..|..|.
 Worm   247 LALDNDN----MSKSRNLTDLVKMIPEID--------------------WIKILKALARHGTSEE 287

  Fly   277 ------HYVMQAQNAKYFTG----LKRLMDSTDAEVVANYIMTRFVLYLIDDFIDSNE------- 324
                  ..|......:||.|    |.|:...|....:|||::.|.::.:...|.|.::
 Worm   288 DEEKLLERVTVHGAGEYFFGENRELARIATETPKSALANYLVVRQLIDVALYFYDKDQPRQNKFY 352

  Fly   325 -HID----CVTDMRRNMNLASNLLYKERFLDPATLQQYTQEVTKVFEQL---------------- 368
             |:|    |.|.:.....:.|..::.|.       .|:..|..||.|::
 Worm   353 NHVDQQSFCATQVASFFPMPSMNVFIES-------SQFKIENLKVIEEMFVKIKAEYEQIFTENE 410

  Fly   369 -----RRQFLL-QIN--ENRLGLTSEQNSMVATKAQHVVLNIGNLPRGRDHRSFVS--RHYEDLV 423
                 .|:||: ::|  :.:.||..........:..:..||.  |......:.::.  ||:.:.:
 Worm   411 YLELEIREFLIRKLNAIDGKFGLDQYTEGKPLLEKMYETLNF--LDTDSPWQVYMKMWRHWSEQL 473

  Fly   424 FPLPDFDYAREHLNLLEFRTRKQVLQLNQSAPTPDEFFYLSDPKTAMSSGPYYLMRLNIIVVPHG 488
            ......|...:.:||..|.|....      .|.|:.|:                     |.:|:
 Worm   474 VEHIVHDTPLDPVNLKMFGTHAAY------QPYPNHFY---------------------INLPY- 510

  Fly   489 LLQEPFFAADSHDIFKYSLLGFVLAHELMHSVDTVGLYYDRYGNIHEIGPQ--------ISSSPR 545
             |..|:..||......|..||:|:.||:.|:.|    ::.|  .:.|.|.|        .||:..
 Worm   511 -LTYPWMDADFPANTNYGYLGYVIGHEIGHAFD----HFHR--KLDESGRQQQYWFTETNSSNTE 568

  Fly   546 FVAGLQCLNRNSTQYLDERI----------ADIAGLDLAYSTYFQNSSQMSLTDFTTIP-----P 595
            :....:||....:.|.:...          .:|||..:...|.|:...::...|...:|     .
 Worm   569 YELREKCLRDQYSAYKEPGYDFFMNGTHCRYEIAGDHMGIRTAFRVFEKVKKEDRFRLPGLEMSE 633

  Fly   596 QQIFFLNLAQFFCG----DGDPINFVG--HDNDETRLQQMLNGFAPFHEAFGCPAKS--NQPEKC 652
            :|:||.|.|...|.    :..|.|.:.  |..:..|:..::.....|.|||.||..|  |...||
 Worm   634 EQLFFYNYAFRQCDVYNPNKLPRNMLARQHPTNRYRVNGVIQNIPEFAEAFNCPKNSPMNPEMKC 698

  Fly   653 QLW 655
            :|:
 Worm   699 KLY 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	42..653	CDD:189000	140/739 (19%)
nep-18	NP_494297.1	PepO	42..692	CDD:226118	142/756 (19%)
		M13	47..699	CDD:189000	142/758 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910