Protein Alignment Nepl6 and nep-6

DIOPT Version :9

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_494537.1
• Gene: nep-6 / 184628
• WormBaseID: WBGene00017550
• Length: 726
• Species: Caenorhabditis elegans
• Alignment Length: 743
• Identity: 150/743 - (20%)
• Similarity: 275/743 - (37%)
• Gaps: 188/743 - (25%)

  Fly    11 PICAAPTTQNVEADPNS-RLMNNILSYVAEDSSACGTYFQYACGKYAVRHRDDPFTEIIQMLDHK 74
            |:..|...:||...|.. .|.:.:|::.......|..:::.|||||:               :|:
 Worm    74 PVTQASKPRNVCETPGCVTLADQLLNFQDPSVDPCQDFYKAACGKYS---------------EHE 123

  Fly    75 VNGNLVQLMHELHQRSQSPGF------NESSVEAKVLHFYRTCR--------EAPPSTRKMEHYL 125
            |....:|....:.|| ....|      :||..|..:...||||.        .|...|...|.:.
 Worm   124 VANRRLQKKDIIIQR-MIKNFLLKNETSESKSENVMRQVYRTCEGLKNEEIFNANMKTAFRELFK 187

  Fly   126 RLAPPGQALTWPQFMPRGEPWPKAQFKWMKSLGHLYRYGFTNVLVNVLVLRSSENSNRFRL-DIS 189
            .:...|.             ||.|...|.::     :.....:|:|::.|.|| |...|:: ...
 Worm   188 DIQKIGS-------------WPAADKNWDET-----KLNLNEMLLNIVKLGSS-NFGLFQIRPTE 233

  Fly   190 MPSLEGDAQHLGGFLSTLATLQIIGVPTKSILPLVRKIRRLESAIRVLTEVDDDDESETWTLRQW 254
            :|.|| .|..:.......|..|.|      |..::.| ..|:....|:.:..:|..:...||.|:
 Worm   234 VPFLE-VAPDMARSPKVSANFQQI------IFDILEK-NGLQPDENVIADDVEDYITLEETLSQY 290

  Fly   255 EY-----KTGYA----------WQGFVESIVG-------------HSVSHHYVMQAQNAKYF--- 288
            .|     |..::          .:..:|.::.             ..|:|      :::.:|
 Worm   291 AYDYNAEKVQFSKLQAQVPSLKLEKIIEEMMNPNRKKLLVTKVKPRMVAH------KHSLFFDEK 349

  Fly   289 TGLKRLMDSTDAEVVANYIMTRFVLYLIDDFIDSNEHIDCVTDMRRNMNLASNLLYKE------- 346
            ..|::|:.||....:|||:    :.|.:|..::             .:::..|::.|.
 Worm   350 MNLEKLLKSTPKRTLANYL----IFYYMDHAMN-------------GLSVHDNVIKKRNCEKLVI 397

  Fly   347 RFLDPATLQQYTQE---------VTKVFEQLRRQFLLQINENR-LGLTSEQNSMVATKAQHVVLN 401
            .:|..|:|:.:.:.         |.::.|:.::.|:..:.|:. ||..|::|:::  |.:.:...
 Worm   398 EYLPKASLRVFVRNHFEKGNLKIVDEMAEETKKSFIEMLQESTWLGADSKKNAIL--KLEKMGKM 460

  Fly   402 IGNLPRGRDHRSFVSRHYEDLVFPLPDFDY------AREHLNL-LEFRTRKQVLQLNQSAPTPDE 459
            || .|:..:.:..:.:.:|.|.....|..|      .|.|:.. :||          .:..||
 Worm   461 IG-YPKEFEKKGALDKMFETLKLLPKDTLYGILKKIGRFHMEQGIEF----------VALETP-- 512

  Fly   460 FFYLSDP-KTAMSSGPYYLMR--LNIIVVPHGLLQEPFFAADSHDIFKYSLLGFVLAHELMHSVD 521
                .|| ...:.:..:|..|  |:.:|   |.:.:|.|.|........:|.|.:||||..|..|
 Worm   513 ----MDPVLPVLMTNAFYTDRNHLSFLV---GYMDDPLFDATYPKYVNIALTGNILAHETSHGFD 570

  Fly   522 TVGLYYDRYGNIHE-IGPQISSSPRFVAGLQCL--------------NRNSTQYLDERIADIAGL 571
            |.|:..|..|.:.. :.|:  ....:....|||              |.|.|..|:|.:||:.|:
 Worm   571 TAGIKRDENGEVRSWMKPE--DLKEYGKKTQCLVDQYNEYDDPVFGKNLNGTTTLNEMVADMIGV 633

  Fly   572 DLAYSTY--FQNSSQMSLTDFTTIPPQQIFFLNLAQFFCGDGDPINFVG-----HDNDETRLQQM 629
            .:|:..:  ..:|.:..:..|......:::|...|..||......:.|.     |.....|:..:
 Worm   634 TVAWKVFEKLDSSKEQKVIGFENENIDKLYFRAAALDFCSLPPTTSLVEELTRVHPTGNFRVNGI 698

  Fly   630 LNGFAPFHEAFGCPAKS--NQPEKCQLW 655
            .:....|..||.||..|  |...:|.::
 Worm   699 FSNMPQFATAFNCPEGSPMNPKTRCSIF 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	42..653	CDD:189000	142/707 (20%)
nep-6	NP_494537.1	M13	105..724	CDD:189000	142/708 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910