Protein Alignment Nepl6 and nep-23

DIOPT Version :10

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_503004.2
• Gene: nep-23 / 178472
• WormBaseID: WBGene00013785
• Length: 714
• Species: Caenorhabditis elegans
• Alignment Length: 707
• Identity: 133/707 - (18%)
• Similarity: 252/707 - (35%)
• Gaps: 156/707 - (22%)

  Fly    29 LMNNILSYVAEDSSACGTYFQYACGKYAVRHRDDPFTEIIQMLDHKVNGNLVQLMHELHQRSQSP 93
            |.:.:.:|....:..|..::|..|||   :|.....:.:.:  .|.:..||::  ..:..|..:|
 Worm    84 LAHQLHNYHDPSADPCDNFYQSVCGK---QHEHSLKSGLAK--KHLILRNLIR--ETITNRKVTP 141

  Fly    94 GFNESSVEAKVLHFYRTC---REAPPSTRKMEHYLR-LAPPGQALTWPQFMPRGEPWPKAQFKWM 154
               .|..|.::..|:..|   :.|..|:...:..|| :....|::         ..||.....|.
 Worm   142 ---TSKSENEMRKFHGICSKYQRANSSSDIAQQALRDIFRDVQSI---------GSWPAGSRNWN 194

  Fly   155 KSLGHLYRYGFTNVLVNVLVLRSSENSNRFRL-----DISMPSLEGDAQHLGGFLSTLATLQIIG 214
            :|..:|      |.::|.||.....|...|::     |..:.|.|...::......|:..:
 Worm   195 ESDFNL------NEMLNNLVKLGQRNFGLFQISFKYRDQLLISAEEHRRNYSKLEPTILNI---- 249

  Fly   215 VPTKSILP----LVRKIR---RLESAIRVLTEVDDDDESETWTLRQWEYKTGYAWQGFVESIVGH 272
            ..|..::|    |::.:.   .||:.::....:|:.|:.:...|.  :......:.|.|::::..
 Worm   250 FETNGLVPDRIQLLKDLEGFASLEALLKNHYYLDNMDKMKPAVLD--DLVPSVDFMGLVKAMISP 312

  Fly   273 SVSH-----HYVMQAQNAKYFT----GLKRLMDSTDAEVVANYIMTRFVLYLIDDFIDSN-EHID 327
            ...|     .......|...|.    .|:.::..|....:||        |||.:||||: :|:.
 Worm   313 GKEHLMPKIELKTSVLNQTLFNDENMNLEAIILDTPKRTLAN--------YLIFNFIDSSLDHLV 369

  Fly   328 CVTDMRRNMNLASNLLYKERFLDPATLQQYTQE---------VTKVFEQLRRQFLLQINENRLGL 383
            ..|..::.......::   .:|..|:|:.:.:.         :|::.|:.|.. |..:.:|...|
 Worm   370 FETTSQKGNTCEDKVI---TYLPRASLRVFIRNYVDKENRDLITQLAEKTRIA-LHTLVQNSTWL 430

  Fly   384 TSEQNSMVATKAQHVVLNIGNLPRGRDHRSFVSRHYEDLVFPLPDFDYAREHLNLLEFRTRKQVL 448
            .:|...:...|...:...||               |.|...|....|...::|||....|....|
 Worm   431 KAESKQLALDKINAMGKMIG---------------YPDFFEPPGTLDGMFKNLNLDSSDTYYTAL 480

  Fly   449 QLNQSAPTPDEFFYLS-----DPK-TAMSSGPYYLM---RLNIIVVPHGLLQEPFFAADSHDIFK 504
            ...:......:..|.:     ||. .......||.:   :||.:.   ....:|.|.:...|...
 Worm   481 NKLERYFVEQKMDYFAEETPLDPDLRVFEMNAYYYIPGNQLNFLA---PFFDDPMFDSTYPDYVN 542

  Fly   505 YSLLGFVLAHELMHSVDTVGLYYDRYGNIHEI-----GPQISSSP----RFVAGLQCLNRNSTQY 560
            .::.|.::.||:.|:          :|. |.|     |.::...|    .:.:..|||....::|
 Worm   543 IAMSGNIIGHEMGHA----------FGP-HAILRTVRGREVWMKPEELAEYESRAQCLANQYSEY 596

  Fly   561 --------------LDERIADIAGLDLAYSTYFQNSSQMSLTDFTTI------PPQQIFFLNLAQ 605
                          :||.:||..|.::::..:    ..:.||:.|.|      ...|::|...|.
 Worm   597 DDPDFGRVFDGGKVIDELVADNIGREVSWKMF----KSLDLTNATRIIGFEDYDIDQLYFRVGAL 657

  Fly   606 FFCGDGDPINFVG-----HDNDETRLQQMLNGFAPFHEAFGCPAKS--NQPEKCQLW 655
            ..|......:..|     |.....|:..:......|..||.||..|  |..:||.::
 Worm   658 THCTPHAMRDLKGSIESSHPRKAFRVNGVYANLPEFARAFNCPTGSPMNPRKKCDMF 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	47..653	CDD:341056	129/685 (19%)
nep-23	NP_503004.2	M13	96..711	CDD:341056	129/690 (19%)