Protein Alignment Nepl6 and nep-16

DIOPT Version :9

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001023203.2
• Gene: nep-16 / 177541
• WormBaseID: WBGene00018472
• Length: 868
• Species: Caenorhabditis elegans
• Alignment Length: 753
• Identity: 141/753 - (18%)
• Similarity: 259/753 - (34%)
• Gaps: 204/753 - (27%)

  Fly     1 MWLIA----------CLFIVPICAAPTTQNVEADP----NSR----LMNNILSYVAEDSSACGTY 47
            :||.|          .||:|.:......:.:.|..    |:|    :...:.|.:.::...|..:
 Worm   196 IWLGALCALFFLLSIALFLVWVITTDGFRTIGAKSTNVCNTRQCIDIAFRLSSCIDDEIEPCENF 260

  Fly    48 FQYACGKYAVRHRDDPFTEIIQMLDHKVNGNLVQLMHELHQRSQSPGFNESSVEAKVLHFYRTCR 112
            ::|:|.:|..:..|...:.:.|:.|..     ::.||.|....:.......|.... ...|..|
 Worm   261 YRYSCQRYHSQTADKQMSFLSQLKDES-----LRRMHSLLSSEEDSRLLPKSARLS-RSLYSAC- 318

  Fly   113 EAPPSTRKMEHYLRLA-PPGQALTWPQFMPRG------EPWPKAQFKWMKSLGHLYRY-GFTNVL 169
                    |...||.: .|...||:.:..|.|      :.:....:.|.:..|.|..| |..|::
 Worm   319 --------MNAVLRSSNAPTDLLTFIRNFPCGPLLRDCQNFHADSYSWERHAGMLDWYAGRYNLI 375

  Fly   170 VNVLVLRSSENSNRFRLDISMPSLEGDAQHLGGFLSTLATLQIIGVPTKSILPLVR--------- 225
            |....:...:.| :..|.|..|.|                ..|:|:..:.::.|.|
 Worm   376 VYDRDVHPQDRS-KIILQIKPPDL----------------TPIVGLIERDLIDLARPSPTEFEPL 423

  Fly   226 ---KIR---------------------RLESAIRVLTEVDDDDESETWTLRQWEYKT-GYAWQG- 264
               .:|                     :|:...|::.::...............|.| |..:|.
 Worm   424 LQLSLRQNLLSAFARDSLLRDPRDVQSQLDEVARLMVDLYISARQSASLTPNTTYMTIGEMFQAL 488

  Fly   265 ---FVESIVGHSVSHHY------VMQAQNAKYFTGLKRLMDSTDAEVVANYIMTRFVLYLIDDFI 320
               ::...:...:|:.|      ::..|:..||..|..:|..|..:.||||::|..|..|.....
 Worm   489 PQLYLREFLDAQLSNTYRWTETDMLSIQDYDYFARLSDIMAQTSRQAVANYLLTVTVWNLKQYSY 553

  Fly   321 DSNEHI---DCVTDMRRNMNLASNLLYKERFLDPAT-------LQQYTQEVTKVFEQLRRQFLLQ 375
            ...:..   :||.      .::|..:.::.::|.|:       :|::.|.:...|..:.|...||
 Worm   554 SPRDQYGWRECVD------QISSFEIGRKMYVDKASQTIDLPKIQEFLQNLKIDFLSVHRSTPLQ 612

  Fly   376 I--NENRLGLTSEQNSMVATKAQHVVLNIGNLPRGRDHRSFVSRHYEDLVFPLPDFDYAREHLNL 438
            .  |.||||                 ..:| .||...:...:.:....:  .|.:.||....:.:
 Worm   613 YLSNINRLG-----------------FYVG-FPRRLQNEELIWKPVSQV--SLNETDYFDSMIRV 657

  Fly   439 LEFRTRKQVLQLNQSAPTPD-EFFYLSDPKTAMSSGPYYLMRLNIIVVPHGLLQEP-FFAADSHD 501
            .:......:.|:.......| ..|.:|||....:|      .:..||:|...::.| :...|...
 Worm   658 GKAERDYTMSQIGTYLDNDDTTTFPISDPTMLYNS------NVGAIVIPLAFIEPPIYLPGDEVP 716

  Fly   502 IFK-YSLLGFVLAHELMHSVDTVGLYYDRYGNIHEIGPQISSSPRFVAGLQCLNRNSTQYLD--- 562
            ::. ||.|| :...:::..|...||  |:                 .:.|:||:.....:||
 Worm   717 MYGIYSSLG-ITTLQMISKVFWQGL--DK-----------------TSQLECLDNVFRGFLDANR 761

  Fly   563 ERIADI-----AGLDLA-------YS-TYFQNS----SQMSLTDFTTIPPQQIFFLNLAQFFC-G 609
            :|..:|     |.::||       || ..:||.    .:.:|..|.:....:...|..:..|| |
 Worm   762 QRSPNIEPELLATIELADAFKSALYSYAKWQNDHHIHHEKTLPAFDSTDSMRSLMLTFSTMFCSG 826

  Fly   610 DG-DPINFVGHDNDETRLQQMLNGFAP----FHEAFGC 642
            :| :|    |.|     .:.|:|..|.    |...|.|
 Worm   827 EGSEP----GSD-----YEAMINTVAENSRMFSIHFNC 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	42..653	CDD:189000	131/694 (19%)
nep-16	NP_001023203.2	GluZincin	254..>725	CDD:387391	95/534 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010