Protein Alignment Nepl6 and nep-3

DIOPT Version :9

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_494679.2
• Gene: nep-3 / 173730
• WormBaseID: WBGene00016778
• Length: 634
• Species: Caenorhabditis elegans
• Alignment Length: 688
• Identity: 135/688 - (19%)
• Similarity: 254/688 - (36%)
• Gaps: 156/688 - (22%)

  Fly    11 PICAAPTTQNVEADPNSRLMNNILSYVAEDSSACGTYFQYACGKYAVRH-----RDDPFTEIIQM 70
            |:|..|..        ..|::.:|::.......|..::|.|||||...:     |.....:|::.
 Worm    60 PMCLTPEC--------ITLVHQLLNFQDPSVDPCENFYQAACGKYNEHNVIDGSRTAQKQQIVKR 116

  Fly    71 LDHKVNGNLVQLMHELHQRSQSPGFNESSVEAKVLHFYRTCREAPPSTRKM--------EHYLRL 127
            |          :...||:...|...:|:|:  |:|  |..|:||  .|.|:        |.::.:
 Worm   117 L----------IRDFLHKNQSSTSKSENSM--KLL--YEKCKEA--KTIKVLGNQNLLQEIFMNI 165

  Fly   128 APPGQALTWPQFMPRGEPWPKAQFKWMKSLGHLYRYGFTNVLVNVLVLRSSENSNRFRLDISMPS 192
            ...|   :||..   .|.|...:|...:.|..|.|.|.:|.....::: ||:.....:...:.|:
 Worm   166 QKIG---SWPVL---DENWDGKKFNLNEMLLSLIRLGVSNFGFFEIII-SSDAFVEIKPARNFPT 223

  Fly   193 LEGDAQHLGGFLSTLATLQIIGVPTKSILPLVRKIRRLESAIRVLTEVDDDDESETWTLRQWEYK 257
            .|.        ||.:.:...:|   ....|.:             |.:::|       ||::|.
 Worm   224 REN--------LSDIISKVFLG---NGFQPNI-------------TAIEND-------LREYEN- 256

  Fly   258 TGYAWQGFVESIVGHSVSHHYVMQAQNAKYFTGLKRLMDSTDAEVVANYIMTRFVLYLIDDF--I 320
                                  :|.:    ...|:||:.:|....:.||::..::..::.::  :
 Worm   257 ----------------------LQRE----LKSLERLIQTTPNRSLVNYLIFNYLKSVMLEYKRL 295

  Fly   321 DSNEHIDCVTDMRRNMNLASNLLYKERFLDPATLQQYTQEVTKVFEQLRRQFLLQINENRLGLTS 385
            ...:....|.|.   :..||..::.:.|||    ::..:.|..:.|.::..|:..|.|: ..|..
 Worm   296 PEEQCEGVVIDF---LPRASTRVFVQNFLD----KENRKYVAGMIEDVKMGFIDMIQES-TWLNE 352

  Fly   386 EQNSMVATKAQHVVLNIGNLPRGRDHRSFVSRHYEDLVFPLPDFDYAREHLNLLEFRTRKQVLQL 450
            |...:...|.:::...||               |.|...|....|.:.:.||:.:..:...:::.
 Worm   353 ESKKVAVQKVKNIKSMIG---------------YPDFFEPPGTLDRSFKDLNIEQTDSYHTIVRK 402

  Fly   451 NQSAPTPDEFFYLS-----DPKTAMSSGPYYLMRLNIIVVPHGLLQEPFFAADSHDIFKYSLLGF 510
            .|.........:::     ||:..:.....:....|.:.:...:|.:|.|..........:::|.
 Worm   403 IQKFTNEQCMEFVASEIPLDPRQPILHANAFYQNTNFLAILAPVLDDPIFDTTFPRYVNLAVIGN 467

  Fly   511 VLAHELMHSVDTVGLYYDRYGNIHEIGPQISSSPRFVAGLQCL--------------NRNSTQYL 561
            |||||:.|:.|..|:.||..|. ..|......|..:...|:||              |.|.::.|
 Worm   468 VLAHEIGHAFDHTGINYDDAGQ-QRIWLTPEDSEEYGKRLRCLLRQHDEYDDPDFGRNLNGSKTL 531

  Fly   562 DERIADIAGLDLAYSTY--FQNSSQMSLTDFTTIPPQQIFFLNLAQFFCGDGDPINFV-----GH 619
            .|..||..|::.|:.|:  ...|::..:..|......|::|...|..:|...|..:..     .|
 Worm   532 HEISADRFGVEAAWRTFKKLDLSNESEIVGFQNFNIDQLYFRTAALIWCRQRDTTDLQYALQREH 596

  Fly   620 DNDETRLQQMLNGFAPFHEAFGCPAKS--NQPEKCQLW 655
            ..:..|:..:......|.|.|.||..|  |..:||.|:
 Worm   597 PTNNFRVNGIYANMPQFAETFNCPLGSPMNPKKKCDLF 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	42..653	CDD:189000	128/653 (20%)
nep-3	NP_494679.2	M13	82..631	CDD:189000	127/653 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910