Protein Alignment Nepl6 and nep-9

DIOPT Version :10

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_494531.2
• Gene: nep-9 / 173683
• WormBaseID: WBGene00017554
• Length: 700
• Species: Caenorhabditis elegans
• Alignment Length: 706
• Identity: 127/706 - (17%)
• Similarity: 263/706 - (37%)
• Gaps: 132/706 - (18%)

  Fly    17 TTQNVEADPNSRLMNNILSYVAEDSSACGTYFQYACGKY-----AVRHRDDPFTEIIQMLDHKVN 76
            |.|..|:.....|...:.:|....:.:|..:::..|..|     ..||||....:.:..|   |.
 Worm    60 TPQFCESPQCIILAQELKAYSDTATKSCEDFYKATCENYKDHQALDRHRDCKKRKAVNKL---VR 121

  Fly    77 GNLVQLMHELHQRSQSPGFNESSVEAKVLHFYRTCREAPPSTRKMEHYLRLAPPGQALTWPQFMP 141
            |.|        ||.:|...:||....|::  :..|.|...:|..::.:..:...|.
 Worm   122 GFL--------QRDESTFTSESESAIKLI--FGKCDELSRNTSYLDIFKDIKKIGS--------- 167

  Fly   142 RGEPWPKAQFKWMKSLGHLYRYGFTNVLVNVLVLRSSENSNRFRLDISMPSLEGDAQHLGGFLST 206
                ||..:..|..|:     :...:|:..::.|.|:: ...|:|::...:.    .|...|:|:
 Worm   168 ----WPVLEHNWKDSM-----FNLDDVIAKLVKLGSTD-FGLFKLELRKLAF----GHFAVFVSS 218

  Fly   207 LATLQIIGVPTKSILPLVRKIRRLESAIRVLTEVDDDDESETWTLRQWEYKTGYAWQGFVESIV- 270
            ... |.|....|:||.:::.....:....:..::.|..:.:......::.:|...::.:..|||
 Worm   219 KQE-QNIHQLEKTILGILKANGIQQDRKELSDDLKDYSDFKNHLKEFYQEETYIEYRLYAGSIVE 282

  Fly   271 ----------------GHSVSHHYVMQA--QNAKYFTG----LKRLMDSTDAEVVANYIMTRFVL 313
                            |..|.:|...:.  .|:..|.|    |..::..|....:||:::..|:.
 Worm   283 NLGISSLTTQMALKSTGLDVFNHVNQRTLITNSSLFFGEENNLGMIIQKTPKRTLANFLIFHFID 347

  Fly   314 YLIDDFIDSNEHIDCVTDMRRNMNLASNLLYKERFLDPATLQQYTQEVTKVFEQLRRQFLLQINE 378
            .:..|..::.:  .|...:...:..||..:....|::    :....::.|:.:.|:.:....|:.
 Worm   348 VMTTDLANATK--ACKETLIDLLPRASIQVLSRNFVN----EDAQDDMVKMAQDLKTKITEMIDN 406

  Fly   379 N------RLGLTSEQNSMVATKAQHVVLNIGNLPRGRDHRSFVSRHYEDLVFPLPDFDYAREHLN 437
            :      .|...:|:...:..|.:.:              ..|:.:.::::    |.|:  |.||
 Worm   407 SPFFTKFHLVFDAEEQKKLIQKVKAI--------------GIVTEYPQEVL----DRDF--ERLN 451

  Fly   438 LLE----FRTRKQVLQLNQSAPTPDEFFYLSDPKTAMSSGPYYLMRLNIIVVPHGLLQEPFFAAD 498
            |..    :||.:::.:|............|....|.:....:|....|.:.:...::..|:|...
 Worm   452 LTPSDSIYRTIQKLRRLRSEQLIEHLGGDLDPTDTRVWGSAHYDQTTNNLTIFAPIIDGPYFDTS 516

  Fly   499 SHDIFKYSLLGFVLAHELMHSVDTVGLYYDRYGNIHE-IGPQISSSPRFVAGLQC---------- 552
            ..:.....|:||:|..||..|:|:|.:..|..|.... :.|:  |..||...|:|
 Worm   517 YPNYVNQFLMGFILGRELGRSLDSVRIRKDEKGQTENWLKPE--SLKRFDEHLKCWAEKYDKSAD 579

  Fly   553 --------LNRNSTQYL-DERIADIAGLDLAYSTYFQ--NSSQMSLTDFTTIPPQQIFFLNLAQF 606
                    :.:...:|: :|..||..|.:.::..:.:  ..::..|..|..|..:::||...|.:
 Worm   580 PLKSESKGIRQIEGRYIQNEMFADFIGHEASWRAFMKLDVKNEEVLETFKVIKLRRMFFNVQALY 644

  Fly   607 FC----GDGDPINFVGHDNDET-RLQQMLNGFAPFHEAFGCPAKS--NQPEKCQLW 655
            ||    |..|.:::..|....: |:.........|..||.|.:..  |...||.::
 Worm   645 FCRPPSGSTDWLSYQEHHQHYSFRVNGAFKNMPQFALAFECASDDDMNPQNKCSMF 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	47..653	CDD:341056	120/672 (18%)
nep-9	NP_494531.2	GluZincin	87..698	CDD:472708	121/675 (18%)