Protein Alignment Nepl6 and nep-13

DIOPT Version :10

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001342017.1
• Gene: nep-13 / 173672
• WormBaseID: WBGene00018196
• Length: 732
• Species: Caenorhabditis elegans
• Alignment Length: 787
• Identity: 152/787 - (19%)
• Similarity: 266/787 - (33%)
• Gaps: 233/787 - (29%)

  Fly     3 LIACLFIVPIC-----------AAP-----TTQNVEADPNS-----RLMNNILSYVAEDSSACGT 46
            :|.||.|:.||           :||     |..|...|...     .|.:.:|::...:...|..
 Worm    45 IIICLVIIAICMGAVIVFWRMDSAPQAICKTDHNKTRDVCKTAECITLSSTLLNWQNTNIDPCED 109

  Fly    47 YFQYACGKYAVRHRDDPFTEIIQMLDHKVNGNL---------VQLMHELHQRSQSPGFNESSVEA 102
            :::|:||:|.               :|.:|..:         ::|:.:...::||   ..|:.|.
 Worm   110 FYEYSCGRYQ---------------EHTLNDGIRANEKDTIVMKLIRQFVLKNQS---TTSNSEN 156

  Fly   103 KVLHFYRTCREAPPSTR-KMEHYLRLAPPGQALTWPQFMPRGEPWPKAQFKWMKSLGHLYRYGFT 166
            .::..|..|     |.| :||:..:.....|...:......|. ||.|...|..|     .:...
 Worm   157 ALMLLYEKC-----SLRYRMENRHQETEVIQREVFENIRKIGS-WPIADKNWNSS-----HFNLN 210

  Fly   167 NVLVNVLVLRSSENSNRFRLDISMPSLEGDAQHLGGF------------LSTLATLQIIGVPT-- 217
            |:|.|                  |.|:     |:..|            ::|.|. |::..||
 Worm   211 NMLSN------------------MASI-----HMLPFGLFETRVIELYPMNTTAK-QLVIRPTKL 251

  Fly   218 KSILP---LVRKIRRLES--AIRVLTEVDDDDESETWTL----------RQWEYKTGYAWQGFVE 267
            |..:|   |||.||.|.|  .|..:.:...:|.:|::.|          .|.:..|....|..|.
 Worm   252 KFSIPQEELVRAIRDLLSVNGITSIMKKVKEDVAESFALDKEIGNIHIDPQPKPATLSELQKAVP 316

  Fly   268 SIVGHSVSHHY--------------VMQAQNAKYF---TGLKRLMDSTDAEVVANYIMTRFVLYL 315
            .|....:...|              :..|:...:|   ..|..::..|...::|||:..:::.|.
 Worm   317 DIDFERIIKSYLNPKTGNWSSLRTKIFSARFELFFGKNNNLSSIIARTKPRILANYLFLKYIEYA 381

  Fly   316 IDDFIDSNEHIDCVTDMRRNMNLASNLLYKERFLDPATLQQYTQEVTKVFEQLRRQFLLQINENR 380
            ...|.|:                 :.:...:.|..........:...:||  :|..|    .:..
 Worm   382 YFFFFDN-----------------TKVFSDDDFCTEVVTTSLPRASLRVF--VRNHF----KKEN 423

  Fly   381 LGLTSEQNSMVATKAQHVVLNIGNLPRGRDHRSFVSRHYEDLVFPLPDFDYAREHLNLLEFRTRK 445
            :.:.||...:|.|....::.|...|     |.|......|.:|.......|..|:..........
 Worm   424 MAVASEIVEVVKTAYVEIINNSTWL-----HNSTRESAIEKVVKMKKVIGYTEEYERTGALDEMF 483

  Fly   446 QVLQLNQSAPTPDEFFYL-----------------SDP-----KTAMSSGPYYLMRLNIIVVPHG 488
            :.|||::|    |.||.|                 ||.     :..:.:..:|....|::.|...
 Worm   484 ETLQLSRS----DSFFVLMTKVNRFKIEQLMDFVSSDSLLNPIEPLVMANAFYFPTKNLLNVLVP 544

  Fly   489 LLQEPFFAADSHDIFKY------SLLGFVLAHELMHSVDTVGLYYDRYGNIHE------------ 535
            .|.:|.|.      |||      :.:|.|||||:.|:.|..|...|..|...:
 Worm   545 FLDKPLFD------FKYPRYVAMAGVGRVLAHEIGHAFDINGRQTDEIGRTRDWWTREDTEEYDR 603

  Fly   536 ----IGPQISS--SPRFVAGLQCLNRNSTQYLDERIADIAGLDLAYSTY--FQNSSQMSLTDFTT 592
                ...|.::  .|.|..     .:|.|:.|.|.|||..|::.::..:  ...:.:..|..|..
 Worm   604 RSECFAEQFTNFKDPSFKG-----KQNGTEVLAEIIADALGMEASWIAFKKINLTEEQGLIQFED 663

  Fly   593 IPPQQIFFLNLAQFFCGD-------GDPINFVGHDNDETRLQQMLNGFAPFHEAFGCP--AKSNQ 648
            ....:::|...|..||..       .|.::   |..::.|:....:....|.:.:.||  :|.|.
 Worm   664 HDFGKLYFQVAALDFCAPSRIEERYSDQLS---HPTNKFRINGAFSNSRAFADTYKCPVGSKMNP 725

  Fly   649 PEKCQLW 655
            .::|.::
 Worm   726 VQRCDMF 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	47..653	CDD:341056	137/718 (19%)
nep-13	NP_001342017.1	M13	104..729	CDD:341056	138/723 (19%)