DRSC/TRiP Functional Genomics Resources

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Protein Alignment Nepl6 and kel

DIOPT Version :9

Sequence 1:NP_609023.3 Gene:Nepl6 / 33893 FlyBaseID:FBgn0259716 Length:655 Species:Drosophila melanogaster
Sequence 2:XP_005157998.1 Gene:kel / 101882278 ZFINID:ZDB-GENE-110411-118 Length:759 Species:Danio rerio


Alignment Length:627 Identity:119/627 - (18%)
Similarity:214/627 - (34%) Gaps:201/627 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 PICAAPTT------QNVEADPNSRLMNNILSYVAEDSSACGTYFQYACG---------KYAVRHR 60
            |:|.:|..      .:|..||.||              .| .||.:|||         :..|:..
Zfish    76 PLCLSPACIRASEHFSVAMDPFSR--------------PC-DYFLFACGAGGSSTNRDRQRVKGE 125

  Fly    61 DDPFTEI-----IQMLD-----HKVNGNL-------VQLMHELHQRSQSP--GFNESSVEAKVLH 106
            .:..:|:     |:|..     .|.:|.|       ..|:..:.:..::|  ..:..:.|.|..:
Zfish   126 VNKHSEVRTRGLIEMRRGTDGWSKSDGQLKTFPDRQTALLTAIKEILEAPDEAVSMGAAEQKAKN 190

  Fly   107 FYRTCREAPPSTRKM--EHYLRLAPP--GQALTWPQFMPRGEPWPKAQFKWMKSL--GHLYRYGF 165
            |:::|..| .|..||  |.:|.|...  |.|::        ..|.:..|....:|  |....:.|
Zfish   191 FFKSCMNA-ESREKMGSEPFLTLLQQLGGWAVS--------GVWNQTDFNSTLALLMGQYSTFPF 246

  Fly   166 TNVLVNVLVLRSSENSNRFRLDISMPSL------------------------------------- 193
            .||.|..........|||..:.|..|..                                     
Zfish   247 FNVYVGPEPSEEQSASNRHYIQIDEPHFQFPIEWNSKTQKAKANTRYLRPFYSACGQYLVLLGVP 311

  Fly   194 -EGDAQHLGGFLSTLATLQIIGVP------------------TKSILPLVRKIRRLESAIRVLTE 239
             :...||.|.|:|...||.:...|                  .:::.|.|..:..|::..:.|. 
Zfish   312 SDRTTQHCGLFVSLSTTLAVATFPLPYRLSQKLLYRRTTIQELQTLAPAVDWLACLQATFQPLL- 375

  Fly   240 VDDDDESETWTLRQWEY-----KTGYAWQGFVESIVGHSVSHHYVMQAQNAKYFTGLKRLMDSTD 299
               ..:|:...:....|     ||.:.|| ....::|....:.|::       |:.|:.|:.:.|
Zfish   376 ---ISKSDIVLVHNLPYIIHMSKTIHLWQ-VQHELMGTGPLNTYMI-------FSLLQTLIPALD 429

  Fly   300 A---EVVANYIMTRFVLYLIDDFIDSNEHIDCVTDMRRNMNLASNLLYKERFLDPATLQQYTQE- 360
            :   :::.||.:.      ..|..:......||....|..:...:...:|:.     .|:..:| 
Zfish   430 SRFFQIMRNYSIA------TGDTQEMPHWWRCVQQTERGFDTLLSHAIREKH-----AQKEAEEL 483

  Fly   361 VTKVFEQLRRQ-------------FLL-QINENRLGLTSEQNSMVATKAQHVVLNIGNLPRGRDH 411
            :..|:..|:::             |:| :||.....:::..|::..|:..|:             
Zfish   484 IQDVYSSLKKKLTDLSWRDEKESDFILNKINSLNPRISTNTNNLSYTELNHL------------- 535

  Fly   412 RSFVSRHYEDLVFPLPDFDYAREHLNLLEFRTRKQVLQLNQSAPTPDEFFYLSDPKTAMSSGPYY 476
                   ||.::....||......:.|||.::|.::|.|.    |..|         .:|..|: 
Zfish   536 -------YEKVILNEEDFFSNYLQILLLEQKSRARLLSLG----TQTE---------GLSMTPF- 579

  Fly   477 LMRLNIIVVPHGLLQEPFFAADSHDIFKYSLLGFVLAHELMH 518
             :..|.|:||.|:...|||.:.......|..||.::|.:|:|
Zfish   580 -ISGNDIIVPVGMFVSPFFHSSYPRALNYGTLGSLMAKDLLH 620

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Nepl6NP_609023.3 M13 42..653 CDD:189000 111/590 (19%)
kelXP_005157998.1 GluZincin 99..>620 CDD:301352 111/602 (18%)
GluZincin 583..>721 CDD:301352 14/38 (37%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11733
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
22.010

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