Protein Alignment Nepl6 and mme

DIOPT Version :10

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_031758820.1
• Gene: mme / 101734885
• XenbaseID: XB-GENE-1011098
• Length: 746
• Species: Xenopus tropicalis
• Alignment Length: 793
• Identity: 169/793 - (21%)
• Similarity: 289/793 - (36%)
• Gaps: 211/793 - (26%)

  Fly     3 LIACLFI----VPICAAPTTQNVEADPNSRLMNNILSYVAEDSSA---CGTYFQYACGKYAVRHR 60
            :|.|:|:    :.:..|..|.|.....:...::.....:|...:|   |..::|||||.:..::|
 Frog    25 IILCIFLGIISIAMILAYATSNDGICTSQACISTAARIIANMDAATDPCNDFYQYACGGWLKKNR 89

  Fly    61 DDPFTEIIQMLDHKVNGNLVQLMHE-----LHQRSQSPGFNESSVEAKVLHFYRTCREAPPSTRK 120
                     :.|:.:..|...::..     |....:....::.....||..||::|.:
 Frog    90 ---------IPDNNIVSNTFDILRTDIEVVLKDALEKESADDIPAIKKVKTFYKSCID------- 138

  Fly   121 MEHYLRLAPPGQALTWPQFMPRGEPWPKAQFKW----------MKSL-GHLYRYGFTNVLVNVLV 174
             |....|...|..:   :.:|....||.|...|          .:|: |.:.:||.:. |:||.|
 Frog   139 -ETIKNLRKGGPLI---KTLPALYDWPIAVDNWETRYGLVWSAQESIAGFITKYGQSG-LINVYV 198

  Fly   175 LRSSENSNRFRLDISMPSLEGDAQHLGGFLSTLATLQIIGVPTK--------------------- 218
            .....||:.:.|.|..|.|                    |:|:|
 Frog   199 SEDLTNSSTYILHIDQPGL--------------------GLPSKDYYDCKGTSEIACLAYMEQMV 243

  Fly   219 SILPLVRKIRRL-----------ESAIRVLTEVDDDDESE--------------------TWTLR 252
            |:..|:||.|.|           |...::..|:...:.||                    |:.|:
 Frog   244 SVAMLIRKERNLTINEDKILSEMEKVFKLEREIAKAEASEEIRENLNDIYKKMTLSGIAKTYPLK 308

  Fly   253 QWEYKTGYAWQGFVESIV---GHSVSHHYVMQAQNAKYFTGLKRLMDSTDAEVVANYIMTRFVLY 314
            ..:....  |...:.:|:   |.|:..:..:....:.|...| |.::...|..:.||:..|::|.
 Frog   309 MNDQNIN--WLKLINAIISPGGVSIEENEQVALICSDYLKKL-RFLNKYKARELQNYLGWRYILS 370

  Fly   315 LIDD----FIDSNEHI---------------DCVTDMRRNMNLASNLLYKERFLDPATLQ--QYT 358
            .|:|    :.::..|:               .|||.:..||..|...||.:..|. |.::  :..
 Frog   371 AINDLSLEYKNTGIHLKKALYGNAAEGSDWQTCVTYLNDNMEDAIGRLYLKETLS-ADIEHVKVK 434

  Fly   359 QEVTKVFEQLRRQFLLQINENRLGLTSEQNSMVATKAQHV---------VLNIGNLPRGRDHRSF 414
            .:|.::..::||.| |::.|....:..:.....|.|...:         :::...|..|
 Frog   435 DKVKEIIAEIRRAF-LEMLEEMDWMDEDTKKRAARKVASINERIAFSEDIMDDFKLNEG------ 492

  Fly   415 VSRHYEDLVFPLPD-FDYAREHLNLLE----FRTRKQVLQLNQSAPTPDEFFYLSDPKTAMSSGP 474
                |.:|.|.:.: |:..::::..::    .|.|||| ..|:..|.|...            ..
 Frog   493 ----YSELEFRVDELFENKQKYIEFVQKKMTSRLRKQV-NKNEWVPGPAHV------------NA 540

  Fly   475 YYLMRLNIIVVPHGLLQEPFFAADSHDIFKYSLLGFVLAHELMHSVDTVGLYYDRYGNIHEIGPQ 539
            :|.:..|.||.|.|:||.|||::.......|..:|.::.||:.|..|..|..:|.:||:......
 Frog   541 FYSLTYNEIVFPAGILQTPFFSSSQPSALNYGGIGMIIGHEITHGFDNRGCNFDEHGNLVNWWTN 605

  Fly   540 ISS------SPRFV----------AGLQCLNRNSTQYLDERIAD---IAGLDLAYSTYFQNSSQM 585
            .|.      |..||          ||.|.||..||  |.|.|:|   |.|...|:..|.::..:.
 Frog   606 ASMMNFSNLSQCFVNQYGNYSWDEAGGQYLNGIST--LGENISDNGGIRGAYRAFKNYVKSHKED 668

  Fly   586 SLTDFTTIPPQQIFFLNLAQFFCGDGDP------INFVGHDNDETRLQQMLNGFAPFHEAFGC-- 642
            .|.....:...|:||::..|.:||...|      |....|.....|:...|.....|.:||.|
 Frog   669 DLLPGIDLDSDQLFFISFGQIWCGMHRPEYAATLIKTGSHTPGIFRVIGTLQNSPEFSKAFSCCN 733

  Fly   643 PAKSNQPEKCQLW 655
            .|..|...||:||
 Frog   734 NAYMNPAVKCKLW 746

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	47..653	CDD:341056	157/738 (21%)
mme	XP_031758820.1	M13	71..744	CDD:341056	158/743 (21%)