Protein Alignment Nepl6 and ece2

DIOPT Version :10

• Sequence 1: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_002935189.1
• Gene: ece2 / 100488407
• XenbaseID: XB-GENE-1011916
• Length: 766
• Species: Xenopus tropicalis
• Alignment Length: 744
• Identity: 166/744 - (22%)
• Similarity: 271/744 - (36%)
• Gaps: 205/744 - (27%)

  Fly    33 ILSYVAEDSSACGTYFQYACGKYAVRH-------RDDPFTEIIQMLDHKVNGNLVQLMHELHQRS 90
            ||..:......|..::||:||.:..|:       |.:.|..|...       |...|.|.|
 Frog   107 ILDSLDRGIDPCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSIWDQ-------NQAILKHIL---- 160

  Fly    91 QSPGFNESS-VEAKVLHFYRTCREAPPSTRKMEHYLRLAPPGQAL----------TWPQFMPRGE 144
            ::..||.|| .|.|...||.:|.:    .:::|. ||..|....:          .|     |||
 Frog   161 ENATFNSSSEAEMKTQRFYLSCLK----EQRIEE-LRQKPLTDLIEKIGGWNISGNW-----RGE 215

  Fly   145 PWPKAQFKWMKSLGHLYR-YGFTNVLVNVLVLRSSENSNRFRLDIS---MPSLE------GDAQH 199
            .:...    :|::...|| ..|.:|.|:  ....|.|||..::|.|   :||.:      .:.:.
 Frog   216 NFMSV----LKTVSGTYRATPFFSVFVS--ADSKSSNSNIIQVDQSGLFLPSRDYYLNKTANGKV 274

  Fly   200 LGGFLSTLATL-QIIGVPTKSILPLVRKIRRLESAIRVLTEVDDD--DESETW---TLRQWE-YK 257
            |..:|..:.:: :::|....|:...:.:|...|:.:..||...|:  ||.:.:   |:.:.: ..
 Frog   275 LDAYLQYMVSVGELLGGSPGSVDMQMTQILEFETLLANLTVPQDERRDEEKIYNRMTISELQSLA 339

  Fly   258 TGYAWQGFV------------ESIVGHSVSHHYVMQAQNAKYFTGLKRLMDSTDAEVVANYIMTR 310
            ..:.|..::            |.:|           ....:|...:..|:::||..::.||::..
 Frog   340 PAFDWMDYLTFALSPLDLNDTEPVV-----------VYGKEYLQQVSELVNNTDPMLLNNYLVWN 393

  Fly   311 FVLYLIDDFIDSNEHIDCVTDMRRNMNLASNLLYKERFLDPATLQQYTQEVTKVFEQL------- 368
            .|                       ..::|:|  ..||       :..|:  |:.|.|
 Frog   394 LV-----------------------QKMSSSL--DSRF-------EKAQD--KLLESLYGAKKSC 424

  Fly   369 --RRQFLLQINENRLGL---------TSEQNS------MVATKAQHVVLNIGNLPRGRDHRSFVS 416
              |.|..|...::.||.         |.::||      |::.......|.:|.|....:.....:
 Frog   425 TPRWQTCLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQMISEIRDAFELTLGGLTWMDEKTRRAA 489

  Fly   417 RHYEDLVFPL---PDFDYAREHL----------------NLLEFRTRKQVLQLNQSAPTPDEFFY 462
            :...|.::.:   |||....:.|                |:|.|......|...|....|:...:
 Frog   490 KEKADAIYDMIGFPDFILDTKELDEVYDGFEVSEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQW 554

  Fly   463 LSDPKTAMSSGPYYLMRLNIIVVPHGLLQEPFFAADSHDIFKYSLLGFVLAHELMHSVDTVGLYY 527
            ...|:|.   ..|||...|.||.|.|:||.||:|........:..:|.|:.|||.|:.|..|..|
 Frog   555 SMTPQTV---NAYYLPNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREY 616

  Fly   528 DRYGNIHEIGP--QISSSPRFVAGLQCL-NR-----------NSTQYLDERIADIAGLDLAYSTY 578
            |..||:.   |  |.||...|....:|: |:           |..|.|.|.|||..||..||..|
 Frog   617 DEDGNLR---PWWQNSSLEAFKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAY 678

  Fly   579 ----FQNSSQMSLTDFTTIPPQQIFFLNLAQFFCG--------DG---DPINFVGHDNDETRLQQ 628
                .::..:..|.. ..:...|:||:..||.:|.        :|   ||     |...:.|:..
 Frog   679 KSWLVKHGEEKQLPG-VGLTNNQLFFVGFAQVWCSVRTPESSHEGLVTDP-----HSPAKFRVIG 737

  Fly   629 MLNGFAPFHEAFGCP--AKSNQPEKCQLW 655
            .|:....|.|.|.||  ...|..:.|.:|
 Frog   738 TLSNSKDFAEHFNCPKGTPMNPGKHCDVW 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl6	NP_609023.3	M13	47..653	CDD:341056	161/726 (22%)
ece2	XP_002935189.1	M13	115..763	CDD:341056	162/731 (22%)