Protein Alignment Nepl5 and Nep5

DIOPT Version :10

• Sequence 1: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Alignment Length: 851
• Identity: 175/851 - (20%)
• Similarity: 305/851 - (35%)
• Gaps: 253/851 - (29%)

  Fly     6 LVAWLIFSLAWRTTPTACRQTNAPQSVQEMLAEQLQSYMDTKARPCENFYQYACGNWQIQQQEQH 70
            |:|.::.||..:.:.:.||.....::     |..|...||.:..|||:|||:.||.|..:.....
  Fly   113 LIAIIVISLGLKKSSSICRSKECLRT-----AASLIYAMDEQTDPCEDFYQFTCGRWANEHPRPD 172

  Fly    71 SLRDRDWTRDRQRYQGQMLPTDTLGLIDHSVNRKLELLLRRRNESSFESDSSILEQMRLYYRSC- 134
            |:...||.|:||.:                :.|.:...||   .:..:|:...:.:.:..||:|
  Fly   173 SVTSNDWFRERQAH----------------IMRVVREFLR---SNITKSEPEAVGKAKTMYRACM 218

  Fly   135 ------KR-LKP---YNLKKYLQLLPPSNSTQWPSVGRGWRPE----RFDWITTLGRLRLHGLNG 185
                  || |:|   |.|:..|.:||.:.:....| |..:..|    :::|:.::..::.|....
  Fly   219 DTKLLDKRDLEPLINYLLRFGLPVLPSALNLTLGS-GSKYATEAANVKYNWLQSIVSIKQHLTMD 282

  Fly   186 VLLREEVLP-----------------------RWDDS---------------------------- 199
            :::..:|.|                       ..|||
  Fly   283 LIIGFDVFPDPFNRTINRIALGTPETDSAFPFNNDDSHKMLRKIHRKTIFMQNSDDEDDSEDDRE 347

  Fly   200 -------------------------RNYSIYVNKPSRQETQPMGEGAMIELLLDIGQTKRTANAL 239
                                     ..|.:||:....||          |..|.|.:..:....:
  Fly   348 SEEEEAAKQTSTGMTAYLHYVRKVIEKYLLYVDPNVNQE----------EATLGITELVKQGVRV 402

  Fly   240 ARQVDDFERKLHR----------------LQELEDDE----GPREMQLGYLDSYLPQLRWLSFMR 284
            ||:|.:|:.:...                ||:|::..    .|:.:.:           |:.:|.
  Fly   403 ARKVHEFKEEAENMTKPSKNPADDIVYITLQDLQNQTDKNIAPKTLPI-----------WVRYME 456

  Fly   285 QV----RIDSELDLRSTLII----ENIPYLRALSDLMESESPDTVCSYIMLKWLAFLKQQGPADI 341
            .:    |....:.:...|.|    .:|.||:.:.:.::......:.||:.|..:.
  Fly   457 LILKGTRHAGNIQMTQNLTIITSQADITYLQNIVEYLDDTPASHIESYLFLSTIE---------- 511

  Fly   342 SRGECVAALRRAMPLASS----WLVGQQFSDPESESYVSSLFQRLKVRFGQILAENRMRLSPPLV 402
               |.|.....:|.|..|    ..:|.:.|.|.|....:.:...|.:....:||:         .
  Fly   512 ---ELVLHTSSSMRLLHSEYMRVAIGTEGSTPRSLYCANGVNSLLGMAVSYVLAD---------A 564

  Fly   403 HILQQKLRAVRLQMG--------FFQTEEIEDVEQYHVRIDLSGH--SFYG------NQLVL--L 449
            ...::||..|...:.        ..::....|.......|..|..  ||.|      |..||  .
  Fly   565 DFTKEKLPKVERMLSDIRRSFDRLVKSTSWMDAATKRKTIQKSAEMKSFIGFPPWLRNASVLNAY 629

  Fly   450 RQRVEANHDLLYINVTNFANSTGSNLSYLSE-------SW--EASNSSPLYVRPRNLVLVPHGLL 505
            .:..|.|......|:.:|.:  ...:..|:|       .|  ..||.:..:....|.:.||..:|
  Fly   630 YEGAEVNASTHLENLMDFVH--WQMMDKLNEMDKPEPIGWATSPSNVNAFHTFQSNAITVPIAIL 692

  Fly   506 QLPIWHRNISALQQHAVMGFVLAHELAHGFDMLGMDYDAMGNIMGPVEEIGASR---QFRQGLQC 567
            |.|.:...:.|| .:..:|.:|.|||.||||..|..:|..||::    |..::|   ::....:|
  Fly   693 QYPFYDLGLEAL-NYGSIGTILGHELTHGFDDSGRRFDRAGNMV----EWWSNRTIDEYVNRTEC 752

  Fly   568 LQQQ-----MATGSKWID------EKLADFVALRLAYETFFGVR------DKREPRDPLLPQFSQ 615
            ..:|     :|...::||      |.:||...:|   |.|:..|      .:...:.|.|..:|.
  Fly   753 FVEQYSRYHLADIDEYIDGELTLGENIADNGGMR---EAFYAYRLYVKEVGRERSKLPGLEHYSH 814

  Fly   616 RQLFFITFAQFFCGR-TPVLSPRSQSEAHLKHAADELRVMQTLANFEEFSREFGCDKKAKMQASQ 679
            .|||||:|...:|.. ||..|..:.:::   |...::|:...|:|.|||:|.|.|.:...|...|
  Fly   815 EQLFFISFGNLWCETYTPAASRYALTDS---HCPGQMRLRGVLSNSEEFARTFKCARGTPMNPDQ 876

  Fly   680 -RCRIW 684
             :||||
  Fly   877 PKCRIW 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl5	NP_609022.1	M13	48..682	CDD:341056	161/805 (20%)
Nep5	NP_733186.2	M13	151..880	CDD:341056	161/804 (20%)