Protein Alignment Nepl5 and Nep2

DIOPT Version :9

• Sequence 1: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Alignment Length: 745
• Identity: 143/745 - (19%)
• Similarity: 274/745 - (36%)
• Gaps: 174/745 - (23%)

  Fly    44 MDTKARPCENFYQYACGNWQIQQQEQHSLRDRDWTRDRQRYQGQMLPTDTLGLIDHSVNRKLELL 108
            |..:..||:|||::|||.:    .|:.::.|            ..:...|..:|...:..:|:.:
  Fly   100 MKPEVEPCDNFYEFACGTY----LEEENIPD------------DKVSISTFSVISDKLQEQLKDI 148

  Fly   109 LRRRNESSFESDSSILEQMRLYYRSCKRLKPYNLKKYLQLLPPSNSTQ-------WPSV-GRGWR 165
            :.....   |::........|.|::|..      |..::.|.|...|:       ||.: |..|.
  Fly   149 ITAERP---ETEPKHFRLPNLLYKACMN------KTLIETLGPEPITRVAERLGGWPLIKGDSWN 204

  Fly   166 -PERFDWITTLGRLRLHGLN---------GVLLREEVLPRWD-DSRNYSI---YVNKPSRQETQP 216
             .:.:.|...:.:.|..|.:         ||.|:.......| |..:.::   |:.|...:....
  Fly   205 ADDSWTWQEQVKKFRTAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSSLALSREYLVKGFNETLVT 269

  Fly   217 MGEGAMIELLLDIGQTKRTANALARQVDDFERKLHRL----------QELEDDEGPREMQLGYLD 271
            .....|:::.:..|..:..|........:||..|..:          .||.:...|.::|..|
  Fly   270 AYYKYMVDIAVLFGANRDLAKTELLLSLEFEMALANISWPNEKRRNSSELYNLRTPAQLQAAY-- 332

  Fly   272 SYLPQLRWLSFMRQVRIDSELDLRSTLIIENIP-YLRALSDLMESESPDTVCSYIMLKW------ 329
               |.::|:.:|..:..:........:|..::| :...|..|:.......:.:|:.  |
  Fly   333 ---PYVQWVDYMNALLPEGLNVAEDEMINLSVPSFFEDLGKLLAKTPKRVIANYMF--WRIHGFS 392

  Fly   330 LAFLK--------QQGPADISRGECVAALRRAMPLASSWL-------------------VGQQFS 367
            :.||.        |...|...|.|..|..:..:.:|:|.:                   ||:.|
  Fly   393 VGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATSSMDEVCEDDFDSLGISVGSLYVGKHF- 456

  Fly   368 DPESESYVSSLFQRLKVRFGQILAE-NRMRLSPPLVHILQQKLRAVRLQMGFFQTEEIEDVEQ-- 429
            ..:|::....:...::..|..||.| |.|.........|  ||.::...:|:  .:|:.|.|:
  Fly   457 HKDSKANALEMVNEIRNVFNDILDEVNWMDAKTKKEAKL--KLHSMATHIGY--PDEMLDNEKLA 517

  Fly   430 -YHVRIDLS---------GHSFYGNQLVLLRQRVEANHDLLYINVTNFANSTGSNLSYLSESWEA 484
             |:.::|:.         |.:.:|......:.|       |.:|.|::....           ..
  Fly   518 AYYAKLDIDPDKYFESFLGMNIFGTDYSFNKLR-------LPVNKTDWVRHA-----------RP 564

  Fly   485 SNSSPLYVRPRNLVLVPHGLLQLPIWHRNISALQQHAVMGFVLAHELAHGFDMLGMDYDAMGNIM 549
            :..:..|....|.:..|.|:||...::...........:|:|:.||:.||||..|..:|..||:.
  Fly   565 AIVNAFYSSLENSIQFPAGILQGHFFNAQRPKYMNFGAIGYVIGHEITHGFDDQGRQFDVKGNLR 629

  Fly   550 G---P-------------VEEIGASRQFRQGLQCLQQQMATGSKWIDEKLADFVALRLAYETFFG 598
            .   |             :|:.|...:...||.      ..|.....|.:||...::.:|..:..
  Fly   630 DWWHPDTQKAYLAKAKCIIEQYGNYTERATGLN------LNGINTQGENIADNGGVKESYIAYRR 688

  Fly   599 VRDKREPRDPLLP--QFSQRQLFFITFAQFFCGRTPVLSPRSQSEAHLK-------HAADELRVM 654
            ..:|..| :..||  .::..|:|::...|.:|.:.     |.:|   ||       |:..|.||:
  Fly   689 WAEKHGP-EAKLPGLDYTPEQMFWVAAGQTWCAKY-----RKES---LKMRITTGVHSPSEFRVL 744

  Fly   655 QTLANFEEFSREFGCDKKAKMQASQRCRIW 684
            .:|:|.::|:::|.|.:.:.|...|:|.:|
  Fly   745 GSLSNMKDFAKDFHCPEGSPMNPVQKCEVW 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl5	NP_609022.1	PepO	42..684	CDD:226118	142/743 (19%)
		GluZincin	48..682	CDD:301352	140/737 (19%)
Nep2	NP_001246914.1	M13	104..772	CDD:189000	140/737 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920