Protein Alignment Nepl5 and Nepl8

DIOPT Version :9

• Sequence 1: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Alignment Length: 725
• Identity: 176/725 - (24%)
• Similarity: 303/725 - (41%)
• Gaps: 157/725 - (21%)

  Fly     9 WLIFSLAWRTTPTACRQTNAPQSVQEMLAEQLQSYMDTKARPCENFYQYACGNWQIQQQEQHSLR 73
            |:|..|   ..|.....:|.      .|...:.|::|.:|.||||:|.:|||        |:::|
  Fly     2 WIICLL---LVPLVAASSNT------RLLNGILSHVDKEANPCENYYNHACG--------QYNMR 49

  Fly    74 DRDWTRDRQRYQGQMLPTDTLGLIDHSVNRKLELLLRRRNESSFESD---SSILEQMRLYYRSCK 135
            ..|.|.           .|.:.::||.||:.|..|:.....||...|   ||:..::..||.||
  Fly    50 HIDDTF-----------FDIIQMLDHQVNQNLVKLMDELEMSSQLPDFNVSSVDGKVLRYYLSC- 102

  Fly   136 RLKPYN---LKKYLQLLPPSNSTQWPSV---GRGWRPERFDWITTLGRLRLHGLNGVLLREEVLP 194
            |..|.|   |.:||:::.|.....||..   |..|..|.|.|:..|..|..:||..|....||:.
  Fly   103 RGAPRNMDSLSQYLKVISPGEGLTWPQFIPDGSSWPQENFKWLKALAHLHRYGLTNVFFNLEVVS 167

  Fly   195 RWDDSRNYSIYVNKPSRQETQPMGEGAMIELL-------------LDIGQTKRTANALAR-QVDD 245
            ...::..|.:.:|.|:..|...: ..:.||:|             :.:.:..||...|.: .::.
  Fly   168 NPRNASEYMVELNTPTFGEESQL-PNSFIEILSVLYIIKVPSSEIITLARKMRTLELLLKTMINP 231

  Fly   246 FERKLHRLQELEDDEGPREMQLGYLDSYLPQLRWLSFMRQVRIDSELDLRSTLIIENIPYLRALS 310
            .:...:|...:.|    .:|:.|:        .|..|. ::.|.|.......:::.|..|..||.
  Fly   232 IDTLNNRYISIRD----FQMETGH--------NWQRFF-EILIGSSAAPELQVLVRNFRYFTALK 283

  Fly   311 DLMESESPDTVCSYIMLKWLAFLKQQGPADISRGECVAALRRAMPLASSWLVGQQFSDPESES-- 373
            :||:.:....|.||||.::..||..:........|||:.:||.|.||::.|..::|.:..:.|
  Fly   284 ELMDKQDARLVASYIMTRFAIFLLDETMGGRESTECVSQVRRNMNLAANMLYKERFFEDSTFSAN 348

  Fly   374 --YVSSLFQRLKVRFGQILAENRMRLSPPLVHILQQKLRAVRLQMGFF--QTEEIE--------- 425
              .:..:|::|:.:|              |:.:.|..|....|||.||  :.|.||
  Fly   349 ILEIKDIFEKLRHQF--------------LLQVDQNHLELTALQMKFFVRKAEAIEINVVNLPKT 399

  Fly   426 -----DVEQYHVRI-----DLSGHSFYGNQLVLLRQRVEANHDLLYINVTNFANSTGSN-LSYLS 479
                 .:.||:..:     :|..|..:...|....|::.|.        ::..:|...| |:|.|
  Fly   400 DDLRHFIGQYYQDLQFPTGELDYHQEHLKVLQFRTQKMLAQ--------SSKGHSEEQNILTYRS 456

  Fly   480 ESWEASNSSPLYVRPRNLVLVPHGLLQLPIWHRNISALQQHAVMGFVLAHELAHGFDMLGMDYDA 544
            :      ::|| ..|:            |.:......:.::::||:::||.|...|...|:...:
  Fly   457 Q------AAPL-PPPQ------------PFFQLESEDVFKYSLMGYIMAHHLISAFATEGITIGS 502

  Fly   545 MGNIMGPVEEIGASRQFRQGLQCLQQQMATGSKWIDEKLADFVALRLAYETFFGVRDKREPRDPL 609
            .||     ::...|.:|.:.:.||.:    .|:.|||.:.|...|.|||.|:..:...|...|
  Fly   503 DGN-----DQSFRSHRFEEAVSCLSR----NSENIDESMGDIAGLELAYFTYAKMAKNRNRLD-- 556

  Fly   610 LPQFSQRQLFFITFAQFFCGRTPVLSPRSQSEAHLKHAADELRVMQTLANFEEFSREFGCDK-KA 673
            .......|:||:...|||||.:.:|         :::..|::|:.:.:..||.|.:.|||.: |.
  Fly   557 FTHLPPEQIFFLNVGQFFCGNSDML---------VQYKEDQVRLQRAIEGFEPFDKAFGCYRNKP 612

  Fly   674 KMQASQRCRI 683
            |   .::||:
  Fly   613 K---HEKCRL 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl5	NP_609022.1	PepO	42..684	CDD:226118	170/692 (25%)
		GluZincin	48..682	CDD:301352	166/683 (24%)
Nepl8	NP_609795.2	GluZincin	32..618	CDD:301352	166/683 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469639
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006719
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840