Protein Alignment Nepl5 and Nepl7

DIOPT Version :9

• Sequence 1: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001285879.1
• Gene: Nepl7 / 34671
• FlyBaseID: FBgn0032442
• Length: 669
• Species: Drosophila melanogaster
• Alignment Length: 756
• Identity: 172/756 - (22%)
• Similarity: 293/756 - (38%)
• Gaps: 167/756 - (22%)

  Fly     1 MLKLSLVAWL----IFSLAWRTTPTACRQTNAPQSVQEMLAEQLQSYMDTKARPCENFYQYACGN 61
            ::.|:|:..:    :|||     |.|   ||..:.:.|.....|.|.|:....||||||:::||.
  Fly     9 LISLTLIGRVLANDLFSL-----PPA---TNHREEMLEDYGRFLLSTMNRTIDPCENFYEFSCGG 65

  Fly    62 WQIQQQEQHSLRDRDWTRDRQRYQGQMLPTDTLGLIDHSVNRKLELLLRRRNESSFE-----SDS 121
            |          :..|...::.|      .|..|..|.|.::.:::..|:...:...|     ..:
  Fly    66 W----------KKADLVPEQAR------NTSFLNAIQHKIDEQIQGFLQNATKRELEDLGVNGTT 114

  Fly   122 SILEQMRLYYRSCKRLKPYNLKKYLQL--------LPPSNSTQWPSVGRGWRPERFDW--ITTLG 176
            |...:.:.:|.||..:|. ||....|.        |...|:|             :||  |..:.
  Fly   115 SAEIKAKQFYASCVEMKA-NLSLGYQYFMEHDGDRLKERNAT-------------YDWMYINFMS 165

  Fly   177 RLRLHGLNGVLLREEVLPRWDDSRNYSIYVNKPS-----------RQETQPMGEGAMIELLLDIG 230
            :..::.|..:.:....     .||.:.|.:..||           :..|:..|..:..|   .:.
  Fly   166 KYDIYPLLALKVHYST-----SSRKFDILLTLPSKVLAGFSEEQLKNMTREFGLDSSAE---KVK 222

  Fly   231 QTKRTANALARQVDDFERKLHRLQELEDDEGPREMQLGYLDSYL----PQLRWLSFMRQVRIDSE 291
            |.....|.|.:    |||.|..|.:..::    ..||.:.:..:    .:|.|..|.       |
  Fly   223 QFVENFNNLTQ----FERNLVSLAKSRNE----TEQLNFKEFLVKHKHDRLNWTRFF-------E 272

  Fly   292 LDLRSTL-----IIENIPYLRALSDLMESESPDTVCSYI----MLKWLAFLKQQGPADISRGECV 347
            |....:.     ::..:..:..|...:|..:.:|:..||    ::|:....|.|......:.||.
  Fly   273 LAFNGSQESHWPVLNQLDNINDLVFFLEQTNLETLKGYIKMRELVKFYGLWKTQTKTGGVQSECR 337

  Fly   348 AALRRAMPLA-SSWLVGQQFSDPESESYVSSLFQRLKVRFGQILAENRMRLSPPLVHILQQKLRA 411
            :........| ..|.:|:.| |.|..:.:.|:.:.:|..|..:| ::...|........:.||.:
  Fly   338 SLSETYFNYALLPWFIGKVF-DKERRADILSVAKDIKDTFYDLL-DHHTWLDEDTRSQAKTKLAS 400

  Fly   412 VRLQMGFFQTEEI---EDVEQYHVRIDLSGHSFYGNQLVLL---RQRVEANHDLLYINVTNFANS 470
            :.:.:|:  |:::   |.::..:..|:::|:.|  ..|.:|   |.|:.             ..|
  Fly   401 MDILVGY--TDDLQHREVIDGVYSDINMTGNWF--ENLCILEGSRARIR-------------LRS 448

  Fly   471 TGSNLSYLSESWEASNSSPLYVRPRNLVLVPHGLLQLPIWHRNISALQQHAVMGFVLAHELAHGF 535
            ....|..|.......|:  .|....||..:..|:.|.|.:|.:...:.::|.:|.::.||:||||
  Fly   449 VDKALIPLLMPTRTVNA--YYADFLNLAFITIGMAQWPFYHIDFPDVLKYAGVGNIIGHEMAHGF 511

  Fly   536 DMLGMDYDAMGNIMGPVEEIGAS---RQFRQGLQCLQQQ---------MATGSKWIDEKLADFVA 588
            |.....|    |..|......:|   |.|::..:||:.|         ...||....:.:||.|.
  Fly   512 DSYCYQY----NYDGKKTNWWSSASLRNFKERYRCLESQYNKFILMGVQTNGSLTSGDNIADNVG 572

  Fly   589 LRLAYETFFGVRDKREPRD------PLL-PQFSQRQLFFITFAQFFCGRTPVLSPRSQSEAHLK- 645
            .|:||..|     ||:..|      ||. ..|:.:||||:.|||.:|..    .........||
  Fly   573 TRMAYYAF-----KRKTGDKAWLEKPLRGVNFNNKQLFFVKFAQTWCNG----KDNGDKLRRLKT 628

  Fly   646 --HAADELRVMQTLANFEEFSREFGCDKKAKMQASQRCRIW 684
              ||.||.||..||:|..|||..|.|....:|...::|.:|
  Fly   629 DVHAYDEFRVQGTLSNMPEFSEAFNCKLGTEMNPLKKCVVW 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl5	NP_609022.1	PepO	42..684	CDD:226118	160/709 (23%)
		GluZincin	48..682	CDD:301352	157/701 (22%)
Nepl7	NP_001285879.1	PepO	43..669	CDD:226118	161/712 (23%)
		M13	52..666	CDD:189000	157/700 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469674
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	1	1.000	-	-		FOG0006719
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850