Protein Alignment Nepl5 and Nepl4

DIOPT Version :10

• Sequence 1: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_609019.1
• Gene: Nepl4 / 33889
• FlyBaseID: FBgn0031805
• Length: 652
• Species: Drosophila melanogaster
• Alignment Length: 723
• Identity: 164/723 - (22%)
• Similarity: 289/723 - (39%)
• Gaps: 169/723 - (23%)

  Fly    23 CRQTNAPQSVQEMLAEQLQSYMDTKARPCENFYQYACGNWQIQQQEQHSLRDRDWTRDRQRYQGQ 87
            |..|     :.:...:.|.||:|::..|||:||.||||.|:.:....
  Fly    38 CNST-----INQQHIDTLMSYVDSEKNPCEDFYAYACGKWRAKHGSH------------------ 79

  Fly    88 MLPTDTLGLIDHSVNRKLELLLRR--RNESSFESDSSILEQMRLYYRSCKRLKPYNLKKYLQLLP 150
               |....:.:..:||:.|.|..:  ||.|:.|....:..::..:|:||..|:..:|::|::||.
  Fly    80 ---TTATMISESQINRQYEDLFLQLLRNPSAPEYGYPMFAKVLAHYQSCIALEKPDLRRYIELLD 141

  Fly   151 PS-----NSTQWPSVGRGWRPERFDWITTLGRLRLHGLNGVLLREEVLPRWDDSRNYSIYVNKPS 210
            ..     |||.|..:           :..|||   :|.:|..::.||  ||.::.::.|::...:
  Fly   142 RDLLASLNSTHWMHL-----------LAALGR---YGYHGHYVQVEV--RWYNATHHMIFLLPHN 190

  Fly   211 RQETQPMGEGAMIELLLDIGQTKRTANALARQVDDFERKLHRLQE----LED-----------DE 260
            |.              |::..|:...:||::....:. .||:|||    ||.           |:
  Fly   191 RH--------------LNLSLTQDIYDALSQDGSSWP-PLHQLQEQFRSLEQNLVRLAKPHSADD 240

  Fly   261 GPREMQLGYLDSYLPQLRWLSFMRQ-----------VRID---------SELDLRSTLIIENIPY 305
            ..|...|..:.:.:|.|.|...:|.           .::|         ..|:...||::.....
  Fly   241 TFRNYSLDQIRTEVPGLHWDEALRTQLGRSVPGNHVFQVDDLDAIEGLVEYLNTVDTLLLNRYSL 305

  Fly   306 LRALSDLME-SESPDTVCSYIMLKWLAFLKQQGPADISRG-ECVAALRRAMPLASSWLVGQQFSD 368
            .|.||.|:| ..:|       :..|     :.|..  ||| .|:..:||::.|..:::..:.|..
  Fly   306 ARFLSHLLELPHNP-------LATW-----ESGQR--SRGRNCIRHMRRSVYLPMNYVYERSFYS 356

  Fly   369 PE---SESYVSSLFQRLKVRFGQILAENRMRLSPPLVHILQQKLRAVRLQMGFFQTEEIEDVEQY 430
            ..   .|..:.|:||:|:.:....:..|...||..||..||.|:..:|:.:|......   .||:
  Fly   357 RRRHADELVIHSVFQQLQSQLELRVQHNAFNLSQDLVKSLQAKVHQMRINVGNLPPNV---TEQF 418

  Fly   431 HVRIDLS---GHSFYGNQLVLLRQRVEANHDLLYINVTNFANSTGSNLSYLSESWEASN------ 486
            :...|..   |..||.|.|          :.|||. .|..|:...|:.....:.|.:.|
  Fly   419 YWDSDRRWSVGRDFYENHL----------NSLLYY-YTLVADLESSSDQEERDIWYSFNMHTPEF 472

  Fly   487 -----SSPLYVRPRNLVLVPHGLLQLPIWHRNISALQQHAVMGFVLAHELAHGFDMLGMDYDAMG 546
                 ::|.:....|::.||:..::.|.:..|......:..:...|.||:.|.||...:||||.|
  Fly   473 PDNIDATPYFYCLGNIIFVPYSYVKRPFFDANFWPALLYGDLANTLGHEIMHAFDTDLVDYDAQG 537

  Fly   547 NIMGPVEEIGASRQFRQGLQCLQQQMATGSKWIDEKLADFVALRLAYETFFGVRDKREPRDPLLP 611
            |:....:::|....:...:.||.    :.:..::|:.:|....|||.:|:.|         ..|.
  Fly   538 NLRNFSDQLGEVELYNGAVGCLN----SSAVMLNERTSDVSGSRLAMQTYGG---------DWLT 589

  Fly   612 QFSQRQLFFITFAQFFCGRTPVLSPRSQSEAHLKHAADELRVMQTLANFEEFSREFGCDKKAKMQ 676
            :....:|:|:.||.||||          .|....|.:...|:...|....:|:..|.|...:.|.
  Fly   590 RSGNGRLYFLQFAHFFCG----------DEGDQYHDSGSQRLNYALGQVPQFAEVFRCHVGSGMT 644

  Fly   677 ASQRCRIW 684
            ::.:|..|
  Fly   645 SADQCPFW 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl5	NP_609022.1	M13	48..682	CDD:341056	156/694 (22%)
Nepl4	NP_609019.1	GluZincin	59..649	CDD:472708	156/692 (23%)