Protein Alignment Nepl5 and Nep6

DIOPT Version :9

• Sequence 1: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001245645.1
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 726
• Identity: 183/726 - (25%)
• Similarity: 302/726 - (41%)
• Gaps: 163/726 - (22%)

  Fly    28 APQSVQEMLAEQLQSYMDTKARPCENFYQYACGNWQIQQQEQ----HSLRDRDWTRDRQRYQGQM 88
            |.|..|    :||.:..|.:.:|||||:|||||||.....::    |.:|.: |.
  Fly    24 AAQDCQ----QQLDNDTDAEVKPCENFHQYACGNWYSNTSQRILGAHDMRSK-WV---------- 73

  Fly    89 LPTDTLGLIDHSVNRKLELLLRRRNES----SFESDSSI---LEQMRLYYRSCKRLKPYNLKKYL 146
                        .|.||: |:|...||    ||.:::|:   ..|:...||.| .|...:::.|.
  Fly    74 ------------ANLKLQ-LIRYLEESSSTDSFSANTSVTTSTAQLGTLYRCC-LLSGQSIRTYT 124

  Fly   147 QLLPPSNSTQWPSVGR---GWRPERFDWITTLGRLRLHGLNGVLLREEVLPRWDDSRNYSIYVNK 208
            ..|..|.: .:|.:..   |    .|||:.....||.:|..| |.|..|...|..:.....|:..
  Fly   125 DALSRSGA-NFPLLANHTGG----SFDWVLANAALRTYGAQG-LWRLLVKDNWQSADQRIFYMLP 183

  Fly   209 P-----SRQE--TQPMGEGAMIELLLDIGQTKRTANALARQVDDFERKLHRL------------- 253
            |     .|.:  .:.:.:..:..|||::|...|.|..||.::..||:.|.:|
  Fly   184 PKFDLLGRDDELNEFLYQRYLKILLLELGLRVRRAALLAEKLVAFEKSLQKLLPNDAEQTLVLRK 248

  Fly   254 -QELEDDEGPREMQLGYLDSYLPQLRWLSFMRQVRIDSELDLRSTLIIENIPYLRALSDLM--ES 315
             |.|:|           |:|.||:|....:...:....:.|.::.|::.::.||:.|..|:  .:
  Fly   249 PQSLKD-----------LESQLPRLELKRYFETILEGIDWDSKTLLLVADLDYLQGLQRLLAEHT 302

  Fly   316 ESPDTVCSYIMLKWLAF----LKQQGPADISRGECVAALRRAMP-----LASSWLVGQQFSD--P 369
            ..|..:.::::|:..|:    |.........|..|:..||:.||     |....::|:.:.|  .
  Fly   303 SDPMVLSTWLLLQLPAYFELRLHDDDKLGNQRNHCLEQLRKLMPGQLGRLQMQLVLGESYQDVYD 367

  Fly   370 ESESYVSSLFQRLKVRFGQILAENRMRLSPPLV--HILQQKLRAVRLQMGFFQTEEIEDVEQYHV 432
            .:...::.||:.||.:|..:|.|..: .:..||  ::.:.||||:||     .|..::|
  Fly   368 TAIQQIAVLFRDLKQQFELVLNETEV-FNEDLVTRNLARDKLRAMRL-----LTPRLQD------ 420

  Fly   433 RIDLSGHSFYGNQLVLLRQRVEANHDLLYINVTNFANSTGSNLSYLSESWEASNSSP-------L 490
              .::|    |.....|....:||  ||.::::.      :.|.|.....|...|.|       .
  Fly   421 --PING----GPGTPQLGGNCDAN--LLQLSLSQ------AKLEYRQVFGEPVTSVPADPLSVNA 471

  Fly   491 YVRPR-NLVLVPHGLLQLPIWHRNIS-----ALQQHAVMGFVLAHELAHGFDMLGMDYDAMGNIM 549
            |.|.: |.:.:|.||:..|:..:..|     ..:..|.:|::||||:.|.||:.|::|||.|.:.
  Fly   472 YYRLKLNRIELPLGLMATPLIQQQCSKEADTRAKLSAGLGYILAHEMVHAFDLDGLNYDATGQLA 536

  Fly   550 GPVEEIGASRQFRQGLQC---LQQQMATGSKWIDEKLADFVALRLAYETF---FGVRDKREPRDP 608
            .  .:..|....|.||:.   |..:.:..:..::|.:||...||||.:|:   .|..:.|
  Fly   537 N--GQWSARAIIRFGLRAGCYLGVRYSNATLTVNENIADTEGLRLALDTYRHRSGATNLR----- 594

  Fly   609 LLPQFSQRQLFFITFAQFFCGRTPVLSPRSQSEAHLKHAADELRVMQTLANFEEFSREFGCDKKA 673
                     .||:.|||.:||.....|..||      ||....||...:.|..||...|.|...:
  Fly   595 ---------TFFVAFAQNWCGTVASTSGLSQ------HAGHAERVNNVVGNMPEFGDTFECKATS 644

  Fly   674 KMQASQRCRIW 684
            :|....:|.||
  Fly   645 QMNPVNKCHIW 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl5	NP_609022.1	PepO	42..684	CDD:226118	176/710 (25%)
		GluZincin	48..682	CDD:301352	174/702 (25%)
Nep6	NP_001245645.1	PepO	35..655	CDD:226118	176/709 (25%)
		M13	40..653	CDD:189000	174/702 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469653
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	1	1.000	-	-		FOG0006719
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850