Protein Alignment Nepl5 and frma

DIOPT Version :9

• Sequence 1: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Alignment Length: 701
• Identity: 170/701 - (24%)
• Similarity: 293/701 - (41%)
• Gaps: 154/701 - (21%)

  Fly    35 MLAEQLQSYMDTKARPCENFYQYACGNWQIQQQEQHSLRDRDWTRDRQRYQGQMLPTDTLGLIDH 99
            :|..|::|:  .:|.||:|||:.|||||    ...|:....:...||               :|:
  Fly    14 LLVVQVKSH--PQADPCQNFYKVACGNW----SASHATDSYESFMDR---------------LDY 57

  Fly   100 SVNRKLELLLRRRNESSFESDSSILEQMRLYYRSCKRLKPYNLKKYLQLLP-----PSNSTQWPS 159
            :...||..||....|   :.:...|:|:|.:|.:|:  ||.:..:.|::|.     .:...:..|
  Fly    58 NYQEKLADLLDNERE---DDEPHFLQQLRNFYTACR--KPLSQDQVLRILEHLIVMENIQNEELS 117

  Fly   160 VGRGWRPERFDWITTLGRLRLHGLNGVLLREEVLPRWDDSRNYSIYVNKPSRQETQPMGEGAMIE 224
            ||          :|...||            :||...:||..|.|:....|.::.
  Fly   118 VG----------LTAAFRL------------QVLIDLNDSNTYDIWKQLMSHRKH---------- 150

  Fly   225 LLLDIGQTKRTANALARQVDD----------------FERKLHRLQEL-----EDDEGPREMQLG 268
              .|...|.|  ..|.|::.|                :.|:|..|:|.     .:|:|   ...|
  Fly   151 --WDPNTTNR--EPLTREMFDKLWASLPKIPFPFKEYYWRELSELEEKIMSYGSEDDG---FDSG 208

  Fly   269 YLDSYLP---QLRW----LSFMRQVRIDSELDLRSTLIIENIPYLRALSDLMESESPDTVCSYIM 326
            .|.:.:|   .:.|    :::....::...||:::...|....|:| |..:.|..|.::
  Fly   209 DLVTRIPPFWMMPWPNGNITYENLSQMAHWLDIKANEFILTYIYMR-LKLVAEGVSTES------ 266

  Fly   327 LKWLAFLKQQGPADISRGECVAALRRAMPLASSWLVGQQFSDPESESYVSSLFQRLKVRFGQILA 391
              |          .|.|.:|....|:.:...::|||.:.....:.|..:..:|..||.||||.|.
  Fly   267 --W----------HIDRDQCAEQSRQILSHPAAWLVEKNHPRLKEEPVLQDIFAELKQRFGQKLL 319

  Fly   392 ENRMRLSPPLVHILQQKLRAVRLQMGFFQTEE-----IEDVEQYHVRIDLSGHSFYGNQLVLLRQ 451
            .||...:....|.|..||:.:||::.......     :..:|:::..:.::...::||      .
  Fly   320 ANRNNFTRSTQHFLLGKLKRMRLRLSILPRNSSAQSMVRRIERHYRDVHMNASDYFGN------L 378

  Fly   452 RVEANHDLLYINVTN-FANSTGSNL--SYLSES--------WEASNSSPLYVRPRNLVLVPHGLL 505
            .:..||...:..... :|...|..|  |.:|:|        ...:.:|..|:..:|:::||..||
  Fly   379 HIGLNHSRSHKKYAQLWAIVFGRQLIPSRISKSDLYPTQVRGYGTYASAFYIVKQNMLIVPLSLL 443

  Fly   506 QLPIWHRNISALQQHAVMGFVLAHELAHGFDMLGMDYDAMGNIMGPVE-EIGASRQFRQGLQCLQ 569
            :.|.:.....::..::.:||:|.|||:||||..||.:.:.|.....|: |:..:.:|:|.|.||:
  Fly   444 EPPFYTHGQPSILTYSALGFILGHELSHGFDSEGMTFSSHGVGSSAVDRELDRNPRFQQELGCLR 508

  Fly   570 QQMATGSKWIDEKLADFVALRLAYETFFGVRDKREPRDPLLPQF-SQRQLFFITFAQFFCGRTPV 633
            ::.  |.|.. ||.||...|.|||..:|........|:....:. :|:|.||..||||||
  Fly   509 RRF--GRKRY-EKFADASGLELAYSAYFDTAQTDHKRNRSAEELVTQKQQFFHNFAQFFC----- 565

  Fly   634 LSPRSQSEAHLKHAADELRVMQTLANFEEFSREFGCDKKAKMQASQRCRIW 684
             |.:...:|| .|.:|..||...:|:||.|...|.|....:   .::||::
  Fly   566 -SDKELLQAH-DHGSDRKRVNDAVAHFEPFREAFSCGPSPR---RRQCRLY 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl5	NP_609022.1	PepO	42..684	CDD:226118	168/692 (24%)
		GluZincin	48..682	CDD:301352	165/684 (24%)
frma	NP_572226.2	GluZincin	25..601	CDD:301352	165/673 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469641
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006719
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940