Protein Alignment Nepl5 and nep-24

DIOPT Version :9

• Sequence 1: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_503005.3
• Gene: nep-24 / 190993
• WormBaseID: WBGene00013786
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 634
• Identity: 127/634 - (20%)
• Similarity: 231/634 - (36%)
• Gaps: 194/634 - (30%)

  Fly    18 TTPTACRQTNAPQSVQEMLAEQLQSYMDTKARPCENFYQYACGNWQIQQQEQHSLRDRDWTRDRQ 82
            |||......|.|..:  .||..|.:|.|....||:||:|:|||     ::.:|...| .:|:..:
 Worm    30 TTPATRNVCNTPACI--TLAHMLHNYHDPSVDPCDNFHQFACG-----REHEHETED-IYTKKTK 86

  Fly    83 RYQGQMLPTDTLGLIDHSVNRKLELLLRRRNESSFESDSSILEQMRLYYRSCKRLKPYNLKKYLQ 147
                             ::|..::..|::...|..:|:::    ||..|::||.|:
 Worm    87 -----------------TINNIMKRFLKKNETSRSKSENA----MRTLYKACKTLE--------- 121

  Fly   148 LLPPSNST------------------QWPSVGRGWRPERFDWITTLGRL-RLHGLNGVLLREEVL 193
                .|||                  .||.|...|...:||....|..| ||...|..|.:   :
 Worm   122 ----KNSTASRNKALQDIFQDIQSIGAWPVVDDKWDESKFDLNDFLVNLVRLGRKNFGLFQ---M 179

  Fly   194 PRWDDSRNYSIYVNKPSRQETQPMGEGAMIELLLDIGQT--------------KRTANALARQVD 244
            .|:.:.||::|             |..|.....:|:|:|              |:..:.||..|
 Worm   180 ARYVNVRNFAI-------------GPEAAWRHNVDLGKTISEILKANSVQTNNKKLLDDLAEYV- 230

  Fly   245 DFERKL--HRLQELEDDEGPREMQLGYLDSYLPQ-LRWLSFMRQVRIDSELDLRS----TLIIE- 301
            :.|:.|  |:.         ..:|.||:.|.... :..::|.|.|     |::.|    ||..|
 Worm   231 NLEKALSQHKF---------NTVQPGYIFSERSDFVSSVNFSRLV-----LEMMSPDKRTLFPEV 281

  Fly   302 -NIPYL----------RALSDLMESESPDTVCSYIMLKWLAFLKQQGPADISRGE----CVAALR 351
             .|.||          ..|..::.:.|...:.:|::.|::    ....||::.|.    |...:.
 Worm   282 YQIMYLTNTSLFFGKNNNLETIIRNTSKRALANYLIFKFI----DTSIADLTYGSPSAFCEQKVI 342

  Fly   352 RAMPLASSWLVGQQFSDPESESYVSSLFQRLKVRFGQIL-AENRMRLSPPLVHILQQKLRAVRLQ 415
            ..:|.|:.....:.|...|:...::.|.:..:|:..:|: |.:.|.:...  .|...::.::.:.
 Worm   343 NFLPRAALRAFYRNFISKENRKKITKLTEATQVQLLKIIGATDWMSIKSK--KIAMDRVSSMNMV 405

  Fly   416 MG---FFQTEEIEDVEQYHVRIDLSGHSFYGNQLVLLRQRVEANHDLLYIN------------VT 465
            :|   :|......|....|:.:. |..::|  .:|....|.....::.|..            :|
 Worm   406 IGYPDYFDPPGKLDGLFEHLNLS-SSDTYY--TVVRKINRFMREQEMDYYTGEVPYYPLFPGLMT 467

  Fly   466 N-FANSTGSNLSYLSESWEASNSSPLYVRPRNLVLVPHGLLQLPIWHRNISALQQHAVMGF---V 526
            | ..|:..:||...:..::    .|.:                      .|:...:|.:.|   .
 Worm   468 NAMYNANDNNLMIFAPFFD----DPFF----------------------DSSFPDYANIAFTSNT 506

  Fly   527 LAHELAHGFDMLGMDYDAMGNIMGPVEEI----GASRQFRQGLQCLQQQ 571
            ||||:.|.|....||      ||....|:    ..:.::.:.::||:.|
 Worm   507 LAHEMGHTFSPHLMD------IMTGTTEVWLTPKETEEYEKRVKCLEDQ 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl5	NP_609022.1	PepO	42..684	CDD:226118	119/610 (20%)
		GluZincin	48..682	CDD:301352	117/604 (19%)
nep-24	NP_503005.3	GluZincin	58..561	CDD:301352	117/604 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920